{"active_ingredient":["Active ingredient Sodium fluoride 0.24% (0.14% w/v fluoride ion)"],"dosage_and_administration":["Directions adults and children 2 years of age and older brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or physician children 2 to 6 years use only a pea sized amount and supervise child's brushing and rinsing (to minimize swallowing) children under 2 years ask a dentist or physician"],"dosage_and_administration_table":["<table width=\"60%\" styleCode=\"Noautorules\"><col width=\"40%\" align=\"left\" valign=\"top\"/><col width=\"60%\" align=\"left\" valign=\"top\"/><tbody><tr styleCode=\"Botrule\"><td styleCode=\"Rrule\">adults and children 2 years of age and older</td><td>brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or physician</td></tr><tr styleCode=\"Botrule\"><td styleCode=\"Rrule\">children 2 to 6 years</td><td>use only a pea sized amount and supervise child&apos;s brushing and rinsing (to minimize swallowing)</td></tr><tr><td styleCode=\"Rrule\">children under 2 years</td><td>ask a dentist or physician</td></tr></tbody></table>"],"effective_time":"20260826","id":"d8d841ad-424d-46c9-a953-9454dddb2a22","inactive_ingredient":["Inactive ingredients Water, Sorbitol, Hydrated Silica, Glycerin, Sodium Lauryl Sulfate, Flavor, Tetrasodium Pyrophosphate, Sodium Saccharin, Cocamidopropyl Betaine, Cellulose Gum, Xanthan Gum, Blue 1."],"indications_and_usage":["Use helps protect against cavities"],"keep_out_of_reach_of_children":["Keep out of reach of children under 6 years of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M021"],"brand_name":["COLGATE 2IN1 ICY BLAST"],"generic_name":["SODIUM FLUORIDE"],"is_original_packager":[true],"manufacturer_name":["Colgate-Palmolive Company"],"package_ndc":["35000-927-81"],"product_ndc":["35000-927"],"product_type":["HUMAN OTC DRUG"],"route":["DENTAL"],"rxcui":["416783"],"spl_id":["d8d841ad-424d-46c9-a953-9454dddb2a22"],"spl_set_id":["6aad9a91-ba1c-4a27-9269-ea8032feaad0"],"substance_name":["SODIUM FLUORIDE"],"unii":["8ZYQ1474W7"],"upc":["0035000764164"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 130 g Bottle Label Colgate ® Anticavity Fluoride Toothpaste 2 in 1 Toothpaste & Mouthwash Cleans Teeth & Freshens Breath Icy Blast ® Whitening LIQUID GEL NET WT 4.6 OZ (130 g) PRINCIPAL DISPLAY PANEL - 130 g Tube Carton"],"purpose":["Purpose Anticavity"],"questions":["Questions? 1-800-468-6502"],"set_id":"6aad9a91-ba1c-4a27-9269-ea8032feaad0","spl_product_data_elements":["COLGATE 2IN1 ICY BLAST SODIUM FLUORIDE SODIUM FLUORIDE FLUORIDE ION WATER SORBITOL HYDRATED SILICA GLYCERIN SODIUM LAURYL SULFATE SODIUM PYROPHOSPHATE SACCHARIN SODIUM COCAMIDOPROPYL BETAINE CARBOXYMETHYLCELLULOSE SODIUM, UNSPECIFIED XANTHAN GUM FD&C BLUE NO. 1"],"spl_unclassified_section":["Drug Facts","Dist. by: COLGATE-PALMOLIVE COMPANY New York, NY 10022 U.S.A."],"version":"4","warnings":["Warnings Keep out of reach of children under 6 years of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away."]}