{"active_ingredient":["Active ingredient Histamine dihydrochloride 0.05% w/w"],"dosage_and_administration":["Directions • adults and children 12 years of age and older: Apply to affected area not more than 3 to 4 times daily • children under 12 years of age: do not use, consult a physician"],"effective_time":"20250219","id":"de7597a0-26c9-4a4b-b2b7-10ded0901117","inactive_ingredient":["Inactive ingredients: Water, Cetearyl alcohol, Emu oil, Glycerin, Ceteareth-20, Glucosamine sulfate, Dimethyl sulfone, Caprylic/capric triglyceride, Phenoxyethanol, Cetyl alcohol, Tocopherol acetate, Butylene glycol, Propylene glycol, Chamomile ( Chamomilla recutita ) flower extract, Rosemary ( Rosemarinus officinalis ) leaf extract, Indian frankincense ( Boswellia serrata ) extract, Ethylhexylglycerin."],"indications_and_usage":["Uses for the temporary relief of minor aches and pains of muscles and joints associated with • simple backache • arthritis • strains • bruises • sprains"],"keep_out_of_reach_of_children":["Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M017"],"brand_name":["Pain Relieving Cream"],"generic_name":["HISTAMINE DIHYDROCHLORIDE"],"is_original_packager":[true],"manufacturer_name":["Mediapower, Inc. DBA Dr Newton's And Naturals"],"package_ndc":["85063-101-85"],"product_ndc":["85063-101"],"product_type":["HUMAN OTC DRUG"],"route":["TOPICAL"],"rxcui":["1542820"],"spl_id":["de7597a0-26c9-4a4b-b2b7-10ded0901117"],"spl_set_id":["9eeea033-ae87-4d83-85d0-b8fa653a0806"],"substance_name":["HISTAMINE DIHYDROCHLORIDE"],"unii":["3POA0Q644U"]},"package_label_principal_display_panel":["Packaging PainRelieving1"],"purpose":["Purpose Pain reliever"],"questions":["Questions or comments? +1-866-788-5951 You may also report serious side effects to this phone number. Mon-Fri 8:00 A.M. - 6:00 P.M."],"set_id":"9eeea033-ae87-4d83-85d0-b8fa653a0806","spl_product_data_elements":["Pain Relieving Cream Histamine Dihydrochloride HISTAMINE DIHYDROCHLORIDE HISTAMINE WATER CETOSTEARYL ALCOHOL EMU OIL GLYCERIN POLYOXYL 20 CETOSTEARYL ETHER GLUCOSAMINE SULFATE DIMETHYL SULFONE MEDIUM-CHAIN TRIGLYCERIDES PHENOXYETHANOL CETYL ALCOHOL .ALPHA.-TOCOPHEROL ACETATE BUTYLENE GLYCOL PROPYLENE GLYCOL CHAMOMILE ROSEMARY INDIAN FRANKINCENSE ETHYLHEXYLGLYCERIN"],"spl_unclassified_section":["Drug Facts","DR. NEWTON'S ™ NATURALS Temporary Pain Relief Moisturizing Cream Odorless, Greaseless, Stainless Distributed by Dr. Newton's Naturals 26 Thomas Drive, Westbrook, ME 04092 To re-order call 800-280-5590 MADE IN USA www.drnewtons.com"],"storage_and_handling":["Other information store between 68° and 77° F (20° and 25° C)"],"version":"1","warnings":["Warnings For external use only Do not use • on wounds or damaged skin • if you are allergic to ingredients in this product When using this product • avoid contact with the eyes. If product gets into the eyes, rinse thoroughly with water • do not bandage tightly or use a heating pad Stop use and ask a doctor if • rash appears • condition worsens, or if symptoms persist for more than 7 days, or if symptoms clear up and occur again within a few days If pregnant or breastfeeding, ask a health professional before use. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."]}