{"active_ingredient":["Active ingredients Carboxymethylcellulose sodium 0.5% Glycerin 0.9%"],"dosage_and_administration":["Directions Instill 1 or 2 drops in the affected eye(s) as needed."],"effective_time":"20220923","id":"eb725fdd-160e-4b82-ad29-e54a6cd6f9e4","inactive_ingredient":["Inactive ingredients Boric acid; calcium chloride dihydrate; erythritol; levocarnitine; magnesium chloride hexahydrate; potassium chloride; purified water; PURITE ® (stabilized oxychloro complex); sodium borate decahydrate; and sodium citrate dihydrate."],"indications_and_usage":["Uses For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun. May be used as a protectant against further irritation."],"keep_out_of_reach_of_children":["Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M018"],"brand_name":["REFRESH OPTIVE"],"generic_name":["CARBOXYMETHYLCELLULOSE SODIUM AND GLYCERIN"],"is_original_packager":[true],"manufacturer_name":["Allergan, Inc."],"nui":["N0000185370","N0000175629","N0000184306","N0000185001","M0000728","M0009417"],"package_ndc":["0023-3240-03","0023-3240-15","0023-3240-01","0023-3240-02"],"pharm_class_cs":["Allergens [CS]","Glycerol [CS]"],"pharm_class_epc":["Non-Standardized Chemical Allergen [EPC]"],"pharm_class_pe":["Increased Histamine Release [PE]","Cell-mediated Immunity [PE]","Increased IgG Production [PE]"],"product_ndc":["0023-3240"],"product_type":["HUMAN OTC DRUG"],"route":["OPHTHALMIC"],"rxcui":["1100650"],"spl_id":["eb725fdd-160e-4b82-ad29-e54a6cd6f9e4"],"spl_set_id":["7f8d88af-fd3b-4138-af61-f24c59ccebd7"],"substance_name":["CARBOXYMETHYLCELLULOSE SODIUM","GLYCERIN"],"unii":["K679OBS311","PDC6A3C0OX"]},"other_safety_information":["Other information Use only if tape seals on top and bottom flaps are intact. Use before expiration date marked on container. Discard 90 days after opening. Store at 59°-77°F (15°-25°C). RETAIN THIS CARTON FOR FUTURE REFERENCE."],"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL 0023-3240-15 Refresh Optive ® Lubricant Eye Drops DUAL-ACTION RELIEF L ubricat es & H ydrat es Dry, Irritated Eyes 0.5 fl oz (15 mL) Sterile 0023-3240-15 Refresh Optive® Lubricant Eye Drops DUAL-ACTION RELIEF Lubricates and hydrates Dry, Irritated Eyes 0.5 fl oz (15 mL) Sterile"],"purpose":["Purpose Eye lubricant Eye lubricant"],"questions":["Questions or comments? 1.800.678.1605 refreshbrand.com v1.0DFL3240"],"set_id":"7f8d88af-fd3b-4138-af61-f24c59ccebd7","spl_product_data_elements":["REFRESH OPTIVE carboxymethylcellulose sodium and glycerin CARBOXYMETHYLCELLULOSE SODIUM CARBOXYMETHYLCELLULOSE GLYCERIN GLYCERIN BORIC ACID CALCIUM CHLORIDE ERYTHRITOL LEVOCARNITINE MAGNESIUM CHLORIDE POTASSIUM CHLORIDE WATER SODIUM CHLORITE SODIUM BORATE TRISODIUM CITRATE DIHYDRATE"],"stop_use":["Stop use and ask a doctor if you experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours."],"version":"12","warnings":["Warnings For external use only. To avoid contamination, do not touch tip of container to any surface. Replace cap after using. If solution changes color or becomes cloudy, d o not use. Stop use and ask a doctor if you experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."]}