{"active_ingredient":["ACTIVE INGREDIENT Hydroquinone 4%","ACTIVE INGREDIENT Hydroquinone 4%","Active ingredient Titanium Dioxide 8%"],"do_not_use":["Do not use on damaged or broken skin."],"dosage_and_administration":["DOSAGE AND ADMINISTRATION After cleansing, apply 2 pumps (1 g) to affected areas twice a day or as directed by a physician. Always use sunscreen protection. (See enclosed package insert for full prescribing information.)","DOSAGE AND ADMINISTRATION Combine 1g tretinoin with 1 pump Melamix™ at night to affected areas or as directed by a physician, directly following Melamin™ for a gradual bleaching of hyperpigmented skin conditions. (See enclosed package insert for full prescribing information.) Mild Start 1-2×/week, increasing as tolerated. Moderate Use every other day, increasing as tolerated. Aggressive Use every AM and PM as tolerated. Always use sunscreen protection.","Directions For full protection, apply liberally 15 minutes before sun exposure. Use a water resistant sunscreen if swimming or sweating. Reapply at least every 2 hours. For children under 6 months of age: ask a doctor. Sun Protection Measures. Spending time in the sun increases your risk off skin cancer and early skin aging. To decrease this risk regularly use a sunscreen with a broad spectrum SPF value of 15 or higher and other sun protection measures including: Limit time in the sun, especially from 10 a.m.- 2 p.m. Wear long-sleeved shirts, pants, hats and sunglasses. Apply to all skin exposed to the sun."],"dosage_and_administration_table":["
MildStart 1-2×/week, increasing as tolerated.
ModerateUse every other day, increasing as tolerated.
AggressiveUse every AM and PM as tolerated. Always use sunscreen protection.
"],"effective_time":"20221214","id":"efcdd64c-192f-e759-e053-2a95a90a8ea3","inactive_ingredient":["INACTIVE INGREDIENTS Water (Aqua), Ascorbic Acid, Glycolic Acid, Cetyl Alcohol, Glycerin, Sodium Lauryl Sulfate, Stearyl Alcohol, Tocopheryl Acetate, BHT, Disodium EDTA, Methylparaben, Propylparaben, Saponins, Sodium Metabisulfite.","INACTIVE INGREDIENTS Water (Aqua), Glycolic Acid, Glycerin, Cetyl Alcohol, Ethylhexyl Palmitate, Ascorbic Acid, Sodium Lauryl Sulfate, Phenyl Trimethicone, Saponins, Tocopheryl Acetate, Methylparaben, Propylparaben, Sodium Metabisulfite, BHT, Disodium EDTA.","Inactive ingredients Water (Aqua), Aluminum Hydroxide, Stearic Acid, Polyglyceryl-3 Polydimethylsiloxyethyl Dimethicone, Cyclopentasiloxane, Phenyl Trimethicone, Styrene/Acrylates Copolymer, Pentylene Glycol, Dimethicone, Glycerin, Isodecyl Neopentanoate, Diisopropyl Sebacate, Lauryl Lactate, Polyacrylamide, Disodium EDTA, Phytosphingosine, Ceteareth-20, Cetearyl Alcohol, PEG-100 Stearate, Glyceryl Stearate, Sodium Dihydroxycetyl Phosphate, Hydrogenated Palm Glycerides, Melanin, Ethylhexylglycerin, Erythritol, Homarine HCL, Sodium Benzoate, Potassium Sorbate, Phenoxyethanol, Caprylyl Glycol, Chlorphenesin, Nephelium Lappaceum Peel Extract, Glycine Soja Extract, Silica, C13-14 Isoparaffin, Laureth-7."],"indications_and_usage":["Uses Helps prevent sunburn. If used as directed with other sun protection measures (see Directions ), decreases the risk of skin cancer and early skin aging caused by the sun."],"keep_out_of_reach_of_children":["Keep out of reach of children. If swallowed, get medical help or contact a poison control center right away."],"openfda":{},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - Kit Carton ZO ® MULTI-THERAPY HYDROQUINONE SYSTEM NDC 42851-131-98 ZO ® MEDICAL BY ZEIN OBAGI, MD RX ONLY Principal Display Panel - Kit Carton"],"purpose":["Purpose Sunscreen"],"set_id":"3f9bd7a0-3aa1-484d-a72a-e75d4f81f7e7","spl_product_data_elements":["ZO MEDICAL ZO MULTI-THERAPY HYDROQUINONE SYSTEM Hydroquinone and Titanium Dioxide MELAMIN Skin Bleaching and Correcting Hydroquinone ASCORBIC ACID BUTYLATED HYDROXYTOLUENE CETYL ALCOHOL EDETATE DISODIUM GLYCERIN GLYCOLIC ACID METHYLPARABEN PROPYLPARABEN WATER SODIUM LAURYL SULFATE SODIUM METABISULFITE STEARYL ALCOHOL .ALPHA.-TOCOPHEROL ACETATE HYDROQUINONE HYDROQUINONE MELAMIX Skin Lightener and Blending Hydroquinone ASCORBIC ACID BUTYLATED HYDROXYTOLUENE CETYL ALCOHOL EDETATE DISODIUM ETHYLHEXYL PALMITATE GLYCERIN GLYCOLIC ACID METHYLPARABEN PHENYL TRIMETHICONE PROPYLPARABEN WATER SODIUM LAURYL SULFATE SODIUM METABISULFITE .ALPHA.-TOCOPHEROL ACETATE HYDROQUINONE HYDROQUINONE ZO MEDICAL OCLIPSE-C Broad-Spectrum Sunscreen SPF 50 TITANIUM DIOXIDE WATER STEARIC ACID POLYGLYCERYL-3 POLYDIMETHYLSILOXYETHYL DIMETHICONE (4000 MPA.S) CYCLOMETHICONE 5 ALUMINUM HYDROXIDE PHENYL TRIMETHICONE EDETATE DISODIUM PENTYLENE GLYCOL DIMETHICONE GLYCERIN LAURYL LACTATE ISODECYL NEOPENTANOATE DIISOPROPYL SEBACATE POLYACRYLAMIDE (1500 MW) SODIUM DIHYDROXYCETYL PHOSPHATE PHYTOSPHINGOSINE HYDROGENATED PALM GLYCERIDES MELAMINE ERYTHRITOL HOMARINE HYDROCHLORIDE NEPHELIUM LAPPACEUM FRUIT RIND SILICON DIOXIDE C13-14 ISOPARAFFIN LAURETH-7 POLYOXYL 20 CETOSTEARYL ETHER CETOSTEARYL ALCOHOL PEG-100 STEARATE GLYCERYL MONOSTEARATE PHENOXYETHANOL CAPRYLYL GLYCOL CHLORPHENESIN ETHYLHEXYLGLYCERIN SODIUM BENZOATE POTASSIUM SORBATE TITANIUM DIOXIDE TITANIUM DIOXIDE ZO MEDICAL GLYCOGENT Exfoliation Accelerator Concentration WATER GLYCOLIC ACID MEDIUM-CHAIN TRIGLYCERIDES LACTIC ACID, UNSPECIFIED FORM SODIUM HYDROXIDE GLYCERIN PROPYLENE GLYCOL CETYL ALCOHOL SQUALANE PROPYLENE GLYCOL MONOSTEARATE STEAPYRIUM CHLORIDE ETHYLHEXYLGLYCERIN ALOE VERA LEAF SAFFLOWER OIL ALLANTOIN GREEN TEA LEAF EDETATE DISODIUM PHENOXYETHANOL SODIUM CARBONATE SODIUM CHLORIDE DIMETHICONE BUTYLENE GLYCOL .ALPHA.-TOCOPHEROL ACETATE VITAMIN A PALMITATE TOCOPHEROL OSSENTIAL DAILY POWER DEFENSE ANTI-AGING FORMULA WATER CETEARYL ISONONANOATE CYCLOMETHICONE 5 CYCLOMETHICONE 6 PENTYLENE GLYCOL RETINOL EGG PHOSPHOLIPIDS POLYSORBATE 20 GLYCERIN STEARETH-20 CETOSTEARYL ALCOHOL JOJOBA BUTTER VITAMIN A PALMITATE .ALPHA.-TOCOPHEROL ACETATE CURDLAN LACTOSE, UNSPECIFIED FORM ORANGE OIL MANDARIN OIL LEMON OIL PEPPERMINT OIL MIMOSA TENUIFLORA BARK ARABIDOPSIS THALIANA C14-22 ALCOHOLS CETEARYL GLUCOSIDE C12-20 ALKYL GLUCOSIDE POWDERED CELLULOSE BUTYLENE GLYCOL PALMITOYL HEXAPEPTIDE-12 PALMITOYL TETRAPEPTIDE-7 SODIUM HYDROXIDE CARBOMER HOMOPOLYMER TYPE C (ALLYL PENTAERYTHRITOL CROSSLINKED) HYPROMELLOSES HEXYLENE GLYCOL EDETATE DISODIUM CAPRYLYL GLYCOL ETHYLHEXYLGLYCERIN PHENOXYETHANOL LIMONENE, (+/-)- ULTRAMARINE BLUE EXT. D&C VIOLET NO. 2"],"spl_unclassified_section":["MELAMIN™ Skin Bleaching & Correcting Crème Indicated for the gradual bleaching of hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines and other unwanted areas of hyperpigmentation.","SUNBURN ALERT This product contains an alpha hydroxy acid (AHA) that may increase your skin's sensitivity to the sun and particularly the possibility of sunburn. Use a sunscreen, wear protective clothing, and limit sun exposure while using this product and for a week afterwards.","MELAMIX™ Skin Lightener & Blending Crème Indicated for the gradual bleaching of hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines and other unwanted areas of hyperpigmentation.","SUNBURN ALERT This product contains an alpha hydroxy acid (AHA) that may increase your skin's sensitivity to the sun and particularly the possibility of sunburn. Use a sunscreen, wear protective clothing, and limit sun exposure while using this product and for a week afterwards.","OCLIPSE-C™ Broad-Spectrum Sunscreen SPF 50 Drug Facts","DIST BY ZO Skin Health, Inc. Irvine, CA 92618"],"stop_use":["Stop and ask a doctor if rash occurs."],"storage_and_handling":["STORAGE Store at controlled room temperature: 15°-30°C (59°-86°F), away from direct sunlight.","STORAGE Store at controlled room temperature: 15°-30°C (59°-86°F), away from direct sunlight.","Other information Store product in a cool place away from direct heat and sunlight. You may report a serious adverse reaction to: 1 Technology Dr. B123, Irvine, CA 92618"],"version":"2","warnings":["WARNINGS Keep out of reach of children. Contains sodium metabisulfite, a sulfite that may cause serious allergic-type reactions including anaphylactic symptoms (e.g. hives, itching), and life threatening or less severe asthmatic episodes in certain susceptible persons. For external use only. Avoid contact with the eyes. Some users may experience a mild skin irritation. If skin irritation becomes severe, stop use and consult a physician. Do not use on children under 12 years of age unless directed by a physician. If swallowed, get medical help or contact a poison control center right away.","WARNINGS Keep out of reach of children. Contains sodium metabisulfite, a sulfite that may cause serious allergic-type reactions including anaphylactic symptoms (e.g. hives, itching), and life threatening or less severe asthmatic episodes in certain susceptible persons. For external use only. Avoid contact with the eyes. Some users may experience a mild skin irritation. If skin irritation becomes severe, stop use and consult a physician. Do not use on children under 12 years of age unless directed by a physician. If swallowed, get medical help or contact a poison control center right away.","Warnings For external use only. Do not use on damaged or broken skin. Stop and ask a doctor if rash occurs. When using this product keep out of eyes. Rinse with water to remove. Keep out of reach of children. If swallowed, get medical help or contact a poison control center right away."],"when_using":["When using this product keep out of eyes. Rinse with water to remove."]}