{"active_ingredient":["ACTIVE INGREDIENTS Sulfur 3.0%"],"dosage_and_administration":["DIRECTIONS clean the skin thoroughly before applying this product cover the entire affected area with a thin layer one to three times daily because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor if bothersome dryness or peeling occurs, reduce application to once a day or every other day."],"effective_time":"20250408","id":"f9116ba0-b9be-4c3c-be76-8b9a6427e739","inactive_ingredient":["INACTIVE INGREDIENTS Aqua (Water), Hamamelis Virginiana (Witch Hazel) Water, Bentonite, Alcohol, Leuconostoc/Radish Root Ferment Filtrate, Acacia Senegal Gum, Caprylyl Glycol, Mentha Piperita (Peppermint) Oil, Melaleuca Alternifolia (Tea Tree) Leaf Oil, Citrus Limon (Lemon) Peel Oil, Alcohol Denat., Mentha Piperita (Peppermint) Leaf Extract Denotes Organic Ingredient , Sodium Gluconate, Bisabolol (L-alpha), Dimethicone, Mentha Viridis (Spearmint) Leaf Oil, Citric Acid, Eucalyptus Globulus Leaf Oil, Allantoin, Citrus Paradisi (Pink Grapefruit) Peel Oil, Aloe Barbadensis Leaf Juice Powder"],"indications_and_usage":["USE for the treatment of acne."],"keep_out_of_reach_of_children":["KEEP OUT OF REACH OF CHILDREN If swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M006"],"brand_name":["TreeActiv Cystic Acne Spot Treatment"],"generic_name":["SULFUR"],"is_original_packager":[true],"manufacturer_name":["Leiluna LLC"],"package_ndc":["72841-201-01","72841-201-02"],"product_ndc":["72841-201"],"product_type":["HUMAN OTC DRUG"],"route":["TOPICAL"],"rxcui":["2636729"],"spl_id":["f9116ba0-b9be-4c3c-be76-8b9a6427e739"],"spl_set_id":["d1b81650-ccc4-49ed-9378-726b3a3a04c7"],"substance_name":["SULFUR"],"unii":["70FD1KFU70"],"upc":["0810016751434"]},"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 15 ML Jar Box TreeActiv Cystic Acne Spot Treatment ACNE TREATMENT SPOT PASTE 0.5 FL OZ (15ML) PRINCIPAL DISPLAY PANEL - 15 ML Jar Box"],"purpose":["Acne Treatment"],"questions":["QUESTIONS? 888-201-6444 | CustomerCare@treeactiv.com"],"set_id":"d1b81650-ccc4-49ed-9378-726b3a3a04c7","spl_product_data_elements":["TreeActiv Cystic Acne Spot Treatment SULFUR SULFUR SULFUR WATER HAMAMELIS VIRGINIANA TOP WATER BENTONITE ALCOHOL LEUCONOSTOC/RADISH ROOT FERMENT FILTRATE ACACIA CAPRYLYL GLYCOL PEPPERMINT OIL TEA TREE OIL LEMON OIL, COLD PRESSED MENTHA PIPERITA LEAF LEVOMENOL SODIUM GLUCONATE DIMETHICONE, UNSPECIFIED SPEARMINT OIL CITRIC ACID MONOHYDRATE EUCALYPTUS OIL ALLANTOIN GRAPEFRUIT OIL ALOE VERA LEAF"],"spl_unclassified_section":["DRUG FACTS"],"version":"4","warnings":["WARNINGS For external use only. Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time. Do not get into eyes. If excessive skin irritation develops or increases, discontinue use and consult a doctor. Apply to affected areas only. Do not use on broken skin or apply to large areas of the body. KEEP OUT OF REACH OF CHILDREN If swallowed, get medical help or contact a Poison Control Center right away."]}