{"active_ingredient":["ACTIVE INGREDIENTS Aesculus hippocastanum 1X Echinacea angustifolia 2X Arnica montana 3X Secale cornutum 3X Viscum album 3X Apis mellifica 4X Baptisia tinctoria 4X Benzoicum acidum 4X Colchicum autumnale 4X Hamamelis virginiana 4X Ruta graveolens 4X Baryta iodata 6X Eupatorium perfoliatum 6X Rhus toxicodendron 6X Solanum nigrum 6X Natrum pyruvicum 8X Arteria 10X Tabacum 10X Cuprum metallicum 13X Sulphur 30X"],"dosage_and_administration":["DIRECTIONS Place drops under tongue 30 minutes before/after meals. Adults and children 12 years and over: Take 10 drops up to 3 times per day. Consult a physician for use in children under 12 years of age."],"effective_time":"20260108","id":"fd8dfec8-ce8a-40dc-a315-a6f117bc6d53","inactive_ingredient":["INACTIVE INGREDIENTS 40% ethanol, purified water."],"indications_and_usage":["INDICATIONS For the temporary relief of occasional constipation, sluggish digestion, minor joint pain or swelling, or sporadic leg pain, particularly when walking.*"],"keep_out_of_reach_of_children":["Keep out of the reach of children."],"openfda":{"brand_name":["Aesculus Combination 9202"],"generic_name":["AESCULUS COMBINATION"],"is_original_packager":[true],"manufacturer_name":["Professional Complementary Health Formulas"],"nui":["N0000185021","N0000175629","N0000184306","N0000185001","M0000728","M0002274","N0000175806","N0000175807","N0000185375","M0016962","M0005152","N0000175831","N0000008595","N0000008924","N0000175830"],"package_ndc":["63083-9202-1"],"pharm_class_cs":["Allergens [CS]","Bee Venoms [CS]","Plant Proteins [CS]","Copper [CS]"],"pharm_class_epc":["Standardized Insect Venom Allergenic Extract [EPC]","Nitrogen Binding Agent [EPC]","Non-Standardized Plant Allergenic Extract [EPC]","Copper-containing Intrauterine Device [EPC]"],"pharm_class_moa":["Ammonium Ion Binding Activity [MoA]"],"pharm_class_pe":["Increased Histamine Release [PE]","Cell-mediated Immunity [PE]","Increased IgG Production [PE]","Decreased Embryonic Implantation [PE]","Decreased Sperm Motility [PE]","Inhibit Ovum Fertilization [PE]"],"product_ndc":["63083-9202"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"spl_id":["fd8dfec8-ce8a-40dc-a315-a6f117bc6d53"],"spl_set_id":["5318d83a-2d8f-4ecc-80ac-d191be5f198f"],"substance_name":["HORSE CHESTNUT","ECHINACEA ANGUSTIFOLIA WHOLE","ARNICA MONTANA WHOLE","CLAVICEPS PURPUREA SCLEROTIUM","AVISCUMINE","APIS MELLIFERA","BAPTISIA TINCTORIA WHOLE","BENZOIC ACID","COLCHICUM AUTUMNALE BULB","HAMAMELIS VIRGINIANA ROOT BARK/STEM BARK","RUTA GRAVEOLENS FLOWERING TOP","BARIUM IODIDE","EUPATORIUM PERFOLIATUM FLOWERING TOP","TOXICODENDRON PUBESCENS LEAF","SOLANUM NIGRUM TOP","SODIUM PYRUVATE","BEEF HEART","TOBACCO LEAF","COPPER","SULFUR"],"unii":["3C18L6RJAZ","VB06AV5US8","O80TY208ZW","01G9XEA93N","4B18YVW82N","7S82P3R43Z","5K1UO2888Y","8SKN0B0MIM","993QHL78E6","T7S323PKJS","N94C2U587S","WKC4T7680A","1W0775VX6E","6IO182RP7A","O4G5C1G3W5","POD38AIF08","P47W069U38","6YR2608RSU","789U1901C5","70FD1KFU70"]},"other_safety_information":["OTHER INFORMATION Tamper resistant. If seal is broken, do not use. After opening, close container tightly and store at room temperature away from heat."],"package_label_principal_display_panel":["LABEL Est 1985 Professional Formulas Complementary Health Aesculus Combination Homeopathic Remedy 1 FL. OZ. (29.5 mL) Label image"],"pregnancy_or_breast_feeding":["If pregnant or breastfeeding, ask a healthcare professional before use."],"purpose":["*Claims based on traditional homeopathic practice, not accepted medical evidence. Not FDA evaluated."],"questions":["QUESTIONS Professional Formulas PO Box 2034 Lake Oswego, OR 97035"],"set_id":"5318d83a-2d8f-4ecc-80ac-d191be5f198f","spl_product_data_elements":["Aesculus Combination 9202 Aesculus Combination HORSE CHESTNUT HORSE CHESTNUT ECHINACEA ANGUSTIFOLIA WHOLE ECHINACEA ANGUSTIFOLIA WHOLE ARNICA MONTANA WHOLE ARNICA MONTANA WHOLE CLAVICEPS PURPUREA SCLEROTIUM CLAVICEPS PURPUREA SCLEROTIUM AVISCUMINE AVISCUMINE APIS MELLIFERA APIS MELLIFERA BAPTISIA TINCTORIA WHOLE BAPTISIA TINCTORIA WHOLE BENZOIC ACID BENZOIC ACID COLCHICUM AUTUMNALE BULB COLCHICUM AUTUMNALE BULB HAMAMELIS VIRGINIANA ROOT BARK/STEM BARK HAMAMELIS VIRGINIANA ROOT BARK/STEM BARK RUTA GRAVEOLENS FLOWERING TOP RUTA GRAVEOLENS FLOWERING TOP BARIUM IODIDE BARIUM CATION EUPATORIUM PERFOLIATUM FLOWERING TOP EUPATORIUM PERFOLIATUM FLOWERING TOP TOXICODENDRON PUBESCENS LEAF TOXICODENDRON PUBESCENS LEAF SOLANUM NIGRUM TOP SOLANUM NIGRUM TOP SODIUM PYRUVATE PYRUVIC ACID BEEF HEART BEEF HEART TOBACCO LEAF TOBACCO LEAF COPPER COPPER SULFUR SULFUR ALCOHOL WATER"],"version":"2","warnings":["WARNINGS In case of overdose, get medical help or contact a poison control center right away. Keep out of the reach of children. If pregnant or breastfeeding, ask a healthcare professional before use."]}