{"active_ingredient":["Active ingredients Carboxymethylcellulose sodium 0.5% Glycerin 0.9%"],"dosage_and_administration":["Directions Instill 1 or 2 drops in the affected eye(s) as needed. Prior to first use, bottle must be primed. Please read the “Instructions For Use” on the insert inside this carton. *Follow your eye doctor’s instructions if you are using this product after an eye surgery (e.g., LASIK) to relieve eye dryness and discomfort."],"effective_time":"20251022","id":"ff3c5118-8815-4ff7-824e-6f748ee321d8","inactive_ingredient":["Inactive ingredients Boric acid; calcium chloride dihydrate; erythritol; levocarnitine; magnesium chloride hexahydrate; potassium chloride; purified water; sodium borate decahydrate; sodium citrate dihydrate; and sodium hyaluronate. May contain hydrochloric acid and/or sodium hydroxide (to adjust pH)."],"indications_and_usage":["Uses For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun. May be used as a protectant against further irritation."],"keep_out_of_reach_of_children":["Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."],"openfda":{"application_number":["M018"],"brand_name":["Refresh Relieva Preservative Free"],"generic_name":["CARBOXYMETHYLCELLULOSE SODIUM AND GLYCERIN"],"is_original_packager":[true],"manufacturer_name":["Allergan, Inc."],"nui":["N0000185370","N0000175629","N0000184306","N0000185001","M0000728","M0009417"],"package_ndc":["0023-6634-10","0023-6634-01","0023-6634-20"],"pharm_class_cs":["Allergens [CS]","Glycerol [CS]"],"pharm_class_epc":["Non-Standardized Chemical Allergen [EPC]"],"pharm_class_pe":["Increased Histamine Release [PE]","Cell-mediated Immunity [PE]","Increased IgG Production [PE]"],"product_ndc":["0023-6634"],"product_type":["HUMAN OTC DRUG"],"route":["OPHTHALMIC"],"rxcui":["1100650"],"spl_id":["ff3c5118-8815-4ff7-824e-6f748ee321d8"],"spl_set_id":["3481f9b3-5a90-40d3-80f8-81f51cc864be"],"substance_name":["CARBOXYMETHYLCELLULOSE SODIUM","GLYCERIN"],"unii":["K679OBS311","PDC6A3C0OX"]},"other_safety_information":["Other information Use only if tape seals on top and bottom flaps are intact. Use before expiration date marked on container. Discard 90 days after opening. Store at 59°-77°F (15°-25°C). RETAIN THIS CARTON AND THE INSERT FOR FUTURE REFERENCE."],"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL NDC: 0023-6634-10 PRESERVATIVE-FREE Refresh R ELIEVA ® PF Lubricant Eye Drops w ith Hydro C ell ® Lubricates &Protects Dry, Sensitive Eyes 0.33 fl oz (10 mL) Sterile PRINCIPAL DISPLAY PANEL NDC: 0023-6634-10 PRESERVATIVE-FREE Refresh RELIEVA® PF Lubricant Eye Drops with HydroCell® Lubricates &Protects Dry, Sensitive Eyes 0.33 fl oz (10 mL) Sterile"],"purpose":["Purpose Eye lubricant Eye lubricant"],"questions":["Questions or comments? v2.0DFL6634 telephone icon and phone number"],"set_id":"3481f9b3-5a90-40d3-80f8-81f51cc864be","spl_product_data_elements":["Refresh Relieva Preservative Free Carboxymethylcellulose sodium and Glycerin CARBOXYMETHYLCELLULOSE SODIUM CARBOXYMETHYLCELLULOSE GLYCERIN GLYCERIN BORIC ACID CALCIUM CHLORIDE ERYTHRITOL LEVOCARNITINE MAGNESIUM CHLORIDE POTASSIUM CHLORIDE WATER SODIUM BORATE TRISODIUM CITRATE DIHYDRATE HYALURONATE SODIUM HYDROCHLORIC ACID SODIUM HYDROXIDE"],"stop_use":["Stop use and ask a doctor if you experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours."],"version":"8","warnings":["Warnings For external use only. To avoid contamination, do not touch tip of contai ner to any surface. Replace cap after using. If solution changes color or becomes cloudy , do not use. Stop use and ask a doctor if you experience eye pain, changes in vision, continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away."]}