{"active_ingredient":["Active ingredient (in each caplet) Loperamide HCl 2 mg"],"ask_doctor":["Ask a doctor before use if you have • fever • mucus in the stool • a history of liver disease • a history of abnormal heart rhythm"],"ask_doctor_or_pharmacist":["Ask a doctor or pharmacist before use if you are taking a prescription drug. Loperamide may interact with certain prescription drugs."],"do_not_use":["Do not use if you have bloody or black stool"],"dosage_and_administration":["Directions • drink plenty of clear fluids to help prevent dehydration caused by diarrhea • find right dose on chart. If possible, use weight to dose; otherwise, use age. adults and children 12 years and over 2 caplets after the first loose stool; 1 caplet after each subsequent loose stool; but no more than 4 caplets in 24 hours children 9-11 years (60-95 lbs) 1 caplet after the first loose stool; 1/2 caplet after each subsequent loose stool; but no more than 3 caplets in 24 hours children 6-8 years (48-59 lbs) 1 caplet after the first loose stool; 1/2 caplet after each subsequent loose stool; but no more than 2 caplets in 24 hours children 2-5 years (34 to 47 lbs) ask a doctor children under 2 years (up to 33 lbs) do not use"],"dosage_and_administration_table":["<table width=\"100%\"><col width=\"29%\"/><col width=\"71%\"/><tbody><tr><td styleCode=\"Rrule Botrule Toprule \" valign=\"top\"><paragraph>adults and children </paragraph><paragraph>12 years and over</paragraph></td><td styleCode=\"Rrule Botrule Lrule Toprule \" valign=\"top\"><paragraph>2 caplets after the first loose stool; 1 caplet after each subsequent loose stool; but no more than 4 caplets in 24 hours</paragraph></td></tr><tr><td styleCode=\"Rrule Botrule \" valign=\"top\"><paragraph>children 9-11 years </paragraph><paragraph>(60-95 lbs)</paragraph></td><td styleCode=\"Rrule Lrule Toprule Botrule \" valign=\"top\"><paragraph>1 caplet after the first loose stool; 1/2 caplet after each subsequent loose stool; but no more than 3 caplets in 24 hours</paragraph></td></tr><tr><td styleCode=\"Rrule Botrule \" valign=\"top\"><paragraph>children 6-8 years </paragraph><paragraph>(48-59 lbs)</paragraph></td><td styleCode=\"Rrule Lrule Toprule Botrule \" valign=\"top\"><paragraph>1 caplet after the first loose stool; 1/2 caplet after each subsequent loose stool; but no more than 2 caplets in 24 hours</paragraph></td></tr><tr><td styleCode=\"Rrule Botrule \" valign=\"top\"><paragraph>children 2-5 years </paragraph><paragraph>(34 to 47 lbs)</paragraph></td><td styleCode=\"Rrule Lrule Toprule Botrule \" valign=\"top\"><paragraph>ask a doctor</paragraph></td></tr><tr><td valign=\"top\"><paragraph>children under 2 years</paragraph><paragraph>(up to 33 lbs)</paragraph></td><td styleCode=\"Rrule Lrule Toprule \" valign=\"top\"><paragraph>do not use</paragraph></td></tr></tbody></table>"],"effective_time":"20250602","id":"ff50896a-db09-41c2-9b91-55009408ff26","inactive_ingredient":["Inactive ingredients anhydrous lactose, carnauba wax, D&C yellow no. 10 aluminum lake, FD&C blue no. 1 aluminum lake, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, pregelatinized starch"],"indications_and_usage":["Use controls symptoms of diarrhea, including Travelers’ Diarrhea"],"keep_out_of_reach_of_children":["Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222)."],"openfda":{"application_number":["ANDA075232"],"brand_name":["Up and Up anti diarrheal"],"generic_name":["LOPERAMIDE HYDROCHLORIDE"],"is_original_packager":[true],"manufacturer_name":["Target Corporation"],"package_ndc":["11673-224-62","11673-224-67","11673-224-02"],"product_ndc":["11673-224"],"product_type":["HUMAN OTC DRUG"],"route":["ORAL"],"rxcui":["978010"],"spl_id":["ff50896a-db09-41c2-9b91-55009408ff26"],"spl_set_id":["ddb70e85-168e-451a-ac04-f6a46721a557"],"substance_name":["LOPERAMIDE HYDROCHLORIDE"],"unii":["77TI35393C"]},"package_label_principal_display_panel":["Principal Display Panel Compare to the active ingredient in Imodium ® A-D Loperamide Hydrochloride Tablets, USP, 2 mg Anti-Diarrheal Anti-diarrheal - controls the symptoms of diarrhea up&up ™ 24 CAPLETS* *CAPSULE-SHAPED TABLETS Actual Size 24 Caplets* up&up-anti-diarrheal-carton-image-1.jpg up&up-anti-diarrheal-carton-image-2.jpg"],"pregnancy_or_breast_feeding":["If pregnant or breast-feeding, ask a health professional before use."],"purpose":["Purpose Anti-diarrheal"],"questions":["Questions or comments? 1-888-547-7400"],"set_id":"ddb70e85-168e-451a-ac04-f6a46721a557","spl_product_data_elements":["Up and Up anti diarrheal Loperamide Hydrochloride LOPERAMIDE HYDROCHLORIDE LOPERAMIDE ANHYDROUS LACTOSE CARNAUBA WAX D&C YELLOW NO. 10 ALUMINUM LAKE FD&C BLUE NO. 1 ALUMINUM LAKE HYPROMELLOSE, UNSPECIFIED MAGNESIUM STEARATE MICROCRYSTALLINE CELLULOSE POLYETHYLENE GLYCOL, UNSPECIFIED L2"],"stop_use":["Stop use and ask a doctor if • symptoms get worse • diarrhea lasts for more than 2 days • you get abdominal swelling or bulging. These may be signs of a serious condition."],"storage_and_handling":["Other information • store at 20°-25°C (68°-77°F) • see end panel for lot number and expiration date"],"version":"10","warnings":["Warnings Allergy alert: Do not use if you have ever had a rash or other allergic reaction to loperamide HCl Heart alert: Taking more than directed can cause serious heart problems or death Do not use if you have bloody or black stool Ask a doctor before use if you have • fever • mucus in the stool • a history of liver disease • a history of abnormal heart rhythm Ask a doctor or pharmacist before use if you are taking a prescription drug. Loperamide may interact with certain prescription drugs. When using this product tiredness, drowsiness or dizziness may occur. Be careful when driving or operating machinery. Stop use and ask a doctor if • symptoms get worse • diarrhea lasts for more than 2 days • you get abdominal swelling or bulging. These may be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222)."],"when_using":["When using this product tiredness, drowsiness or dizziness may occur. Be careful when driving or operating machinery."]}