BIOLOGIC-DT SYSTEM DT-1000

MAUDE Adverse Event Report

MAUDE data represents reports of adverse events involving medical devices. This maude entry was filed from a 01,08 report with the FDA on 1997-11-26 for BIOLOGIC-DT SYSTEM DT-1000 manufactured by Hemocleanse, Inc..

Event Text Entries

[100634] Hemocleanse inc customer complaint rec'd on 10/31/1997, stated that during a standard treatment of a 26 yr old male suffering from acute hepatic failure secondary to a bone marrow transplant for leukemia, blood flow rates, as measured by the biologic-dt machine, suddenly dropped from normal to very low. In this event the operator's manual instructs the user to 1) check the pt vascular access for kinks, 2) check the disposable tubing for obstructions, and if no problem becomes evident 3) press "rinse" and add heparin if indicated by reduced act (parameters also provided in labeling). After checking the catheter, flows reportedly improved but between the treatment time of four hrs and five hrs the problem resurfaced. The operator's manual again states to "rinse", but if low blood flow persists, the treatment should be terminated. The treatment was eventually terminated at five and one half hrs. Normal treatment time is six hrs. The initial rptr of the event state that multiple untrained nurses were involved in the treatment, and that the physician in charge had to leave the scene. The machine had originally been programmed to remove 1000 ml of ultrafiltrate from the pt, but seven or eight rinses were performed by the various nurses caring for the pt. Because any particular nurse was unaware of the actions of another, the pt ended up with a resultant positive fluid balance of 450 ml (0. 9% normal saline). It is reported that the next morning the pt developed pulmonary edema. It is assumed that normal intervention for pulmonary edema was performed but more info is required. The pt expired two days later; however, the rptr noted that death was not a result of the incident.
Patient Sequence No: 1, Text Type: D, B5


MAUDE Entry Details

Report Number1835219-1997-00001
MDR Report Key135113
Report Source01,08
Date Received1997-11-26
Date of Event1997-10-30
Date Mfgr Received1997-10-31
Device Manufacturer Date1997-03-01
Date Added to Maude1997-12-02
Event Key0
Report Source CodeManufacturer report
Manufacturer LinkY
Number of Patients in Event0
Adverse Event Flag3
Product Problem Flag3
Reprocessed and Reused Flag0
Health Professional3
Initial Report to FDA3
Report to FDA3
Event Location0
Single Use3
Previous Use Code3
Event Type3
Type of Report3

Device Details

Brand NameBIOLOGIC-DT SYSTEM
Generic NameBLOOD DETOXIFICATION SYSTEM
Product CodeFKT
Date Received1997-11-26
Model NumberDT-1000
Catalog NumberDT-1000
Lot Number*
ID Number*
Device Expiration Date1998-02-01
OperatorHEALTH PROFESSIONAL
Device AvailabilityN
Device Eval'ed by MfgrR
Implant FlagN
Date Removed*
Device Sequence No1
Device Event Key132011
ManufacturerHEMOCLEANSE, INC.
Manufacturer Address2700 KENT AVE. W. LAFAYETTE IN 47906 US
Baseline Brand NameBIOLOGIC-DT SYSTEM
Baseline Generic NameBLOOD DETOXIFICATION SYSTEM
Baseline Model NoDT-1000
Baseline Catalog NoDT-1000
Baseline ID*


Patients

Patient NumberTreatmentOutcomeDate
101. Required No Informationntervention 1997-11-26

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