Depo-Estradiol

Product NDC
0009-0271
11-digit product format
000090271
Labeler code
0009
Product ID
0009-0271_70957ffe-7710-4a3a-98fa-bf5d84f38ddb
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
estradiol cypionate
Dosage form
INJECTION
Route
INTRAMUSCULAR
Labeler
Pharmacia & Upjohn Company LLC
Application
ANDA085470
Marketing category
ANDA
Marketing start
1979-08-15
Substance
ESTRADIOL CYPIONATE
Active strength
5 mg/mL
Pharmacologic classes
Estradiol Congeners [CS], Estrogen Receptor Agonists [MoA], Estrogen [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A085470-001DEPO-ESTRADIOLESTRADIOL CYPIONATE1MG/MLINJECTABLE / INJECTIONApproved before 1982
A085470-002DEPO-ESTRADIOLESTRADIOL CYPIONATE3MG/MLINJECTABLE / INJECTIONApproved before 1982
A085470-003DEPO-ESTRADIOLESTRADIOL CYPIONATE5MG/MLINJECTABLE / INJECTIONRS, Approved before 1982

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A085470-001DEPO-ESTRADIOL1MG/MLINJECTABLE / INJECTIONApproved before 1982011fe1cb6892…
2026-02-19 14:30 UTC2026-02A085470-002DEPO-ESTRADIOL3MG/MLINJECTABLE / INJECTIONApproved before 1982011fe1cb6892…
2026-02-19 14:30 UTC2026-02A085470-003DEPO-ESTRADIOL5MG/MLINJECTABLE / INJECTIONRS, Approved before 1982011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A085470-001DEPO-ESTRADIOL1MG/MLINJECTABLE / INJECTIONApproved before 198231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A085470-002DEPO-ESTRADIOL3MG/MLINJECTABLE / INJECTIONApproved before 198231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A085470-003DEPO-ESTRADIOL5MG/MLINJECTABLE / INJECTIONRS, Approved before 198231067a03dcf5…
2025-08-23 18:47 UTC2025-08A085470-001DEPO-ESTRADIOL1MG/MLINJECTABLE / INJECTIONApproved before 19826a471c1ec25d…
2025-08-23 18:47 UTC2025-08A085470-002DEPO-ESTRADIOL3MG/MLINJECTABLE / INJECTIONApproved before 19826a471c1ec25d…
2025-08-23 18:47 UTC2025-08A085470-003DEPO-ESTRADIOL5MG/MLINJECTABLE / INJECTIONRS, Approved before 19826a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A085470-001DEPO-ESTRADIOL1MG/MLINJECTABLE / INJECTIONApproved before 1982fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A085470-002DEPO-ESTRADIOL3MG/MLINJECTABLE / INJECTIONApproved before 1982fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A085470-003DEPO-ESTRADIOL5MG/MLINJECTABLE / INJECTIONRS, Approved before 1982fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A085470-001DEPO-ESTRADIOL1MG/MLINJECTABLE / INJECTIONApproved before 1982b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A085470-002DEPO-ESTRADIOL3MG/MLINJECTABLE / INJECTIONApproved before 1982b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A085470-003DEPO-ESTRADIOL5MG/MLINJECTABLE / INJECTIONRS, Approved before 1982b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A085470-001DEPO-ESTRADIOL1MG/MLINJECTABLE / INJECTIONApproved before 198203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A085470-002DEPO-ESTRADIOL3MG/MLINJECTABLE / INJECTIONApproved before 198203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A085470-003DEPO-ESTRADIOL5MG/MLINJECTABLE / INJECTIONRS, Approved before 198203ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A085470-001DEPO-ESTRADIOL1MG/MLINJECTABLE / INJECTIONApproved before 19822680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A085470-002DEPO-ESTRADIOL3MG/MLINJECTABLE / INJECTIONApproved before 19822680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A085470-003DEPO-ESTRADIOL5MG/MLINJECTABLE / INJECTIONRS, Approved before 19822680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A085470-001DEPO-ESTRADIOL1MG/MLINJECTABLE / INJECTIONApproved before 19825bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A085470-002DEPO-ESTRADIOL3MG/MLINJECTABLE / INJECTIONApproved before 19825bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A085470-003DEPO-ESTRADIOL5MG/MLINJECTABLE / INJECTIONRS, Approved before 19825bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A085470-001DEPO-ESTRADIOL1MG/MLINJECTABLE / INJECTIONApproved before 1982d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A085470-002DEPO-ESTRADIOL3MG/MLINJECTABLE / INJECTIONApproved before 1982d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A085470-003DEPO-ESTRADIOL5MG/MLINJECTABLE / INJECTIONRS, Approved before 1982d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A085470-001DEPO-ESTRADIOL1MG/MLINJECTABLE / INJECTIONApproved before 1982d06236e962d9…
2024-10-29 15:01 UTC2024-10A085470-002DEPO-ESTRADIOL3MG/MLINJECTABLE / INJECTIONApproved before 1982d06236e962d9…
2024-10-29 15:01 UTC2024-10A085470-003DEPO-ESTRADIOL5MG/MLINJECTABLE / INJECTIONRS, Approved before 1982d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A085470-001DEPO-ESTRADIOL1MG/MLINJECTABLE / INJECTIONApproved before 198279d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A085470-002DEPO-ESTRADIOL3MG/MLINJECTABLE / INJECTIONApproved before 198279d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A085470-003DEPO-ESTRADIOL5MG/MLINJECTABLE / INJECTIONRS, Approved before 198279d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A085470-001DEPO-ESTRADIOL1MG/MLINJECTABLE / INJECTIONApproved before 1982301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A085470-002DEPO-ESTRADIOL3MG/MLINJECTABLE / INJECTIONApproved before 1982301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A085470-003DEPO-ESTRADIOL5MG/MLINJECTABLE / INJECTIONRS, Approved before 1982301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A085470-001DEPO-ESTRADIOL1MG/MLINJECTABLE / INJECTIONApproved before 19821e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A085470-002DEPO-ESTRADIOL3MG/MLINJECTABLE / INJECTIONApproved before 19821e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A085470-003DEPO-ESTRADIOL5MG/MLINJECTABLE / INJECTIONRS, Approved before 19821e350fbaab3a…
2024-05-31 18:47 UTC2024-05A085470-001DEPO-ESTRADIOL1MG/MLINJECTABLE / INJECTIONApproved before 19828072bd15b7f6…

Additional Listing Data#

Finished product
Yes
Brand name base
Depo-Estradiol
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
ESTRADIOL CYPIONATE5 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
7E1DV054LOInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
206417Internal RxNorm lookup
310187Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
9a4229fd-fecd-4ac1-9c4f-6d442533457fAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
5bec24fd-caeb-8b32-1ff0-ca0dd1751379Product name220250618
3fcaf367-cbc2-4d1e-845e-e1ce4b0d86a6Product name220250616
4ca088c7-0c0e-114d-ffaa-d1b94f9eadc1Product name620250311
99d68ea7-fba4-0d7b-b5fa-468e21dd1cbfProduct name220250204
a1c50ef5-9c2c-d846-1ca1-70fabf2428e1Product name320240507
66263a7f-f64d-41c4-90f1-2cee106617ccProduct name120240501
76820076-f087-4073-b1d1-aa04b361335eProduct name220220921
132e7bcf-ca42-94e4-3c78-c44ae7819a94Product name320220126
0a040ba8-1f34-4328-bb07-4f64503daaabProduct name220210513
833edb59-a012-45c2-aff5-2ed74b66fa59Product name120201207
f4d31098-441e-52d3-27f1-49c829f8a3a1Product name520190703
001f367b-fa14-49a0-865b-b395f2553601Product name220190611
3f090665-4687-4bb4-8790-8efb1930ee74Product name120180801
7a549f52-8b99-472c-8b1d-3a70c53c9bf4Product name120160623
3ca8d96e-517a-05ea-5690-f8e1d3726540Product name120140508
5f44c957-835a-ada0-662f-5b1071b7a68bProduct name120140508
7d6c8f26-fe65-2465-c993-66dd6e1c1183Product name120140508
83cac4be-cfee-33c1-5b8e-bb83ae18bce4Product name120140508
c3f7be78-e6d7-47c9-c840-70c566e8d5c4Product name120140508
d6b36b6b-65d6-a810-0fa7-61ddf1a96352Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0009-0271-01Depo-Estradiol1 in 1 CARTONINJECTION19
0009-0271-01Depo-Estradiol5 mL in 1 VIALINJECTION59

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0009-0271-01ML - Milliliter0009-0271690dae16-9776-4248-8671-a6c7cfa6795e12012-07-24

DailyMed Socrata Ingredients#

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0009-0271DEPO-ESTRADIOL (ESTRADIOL CYPIONATE) INJECTION [PHARMACIA & UPJOHN COMPANY LLC]9Current NDC, Legacy NDC, 2 package rows20240229_9a4229fd-fecd-4ac1-9c4f-6d442533457f.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Depo-EstradiolESTRADIOL CYPIONATEPharmacia & Upjohn Company LLC9a4229fd-fecd-4ac1-9c4f-6d442533457f2024-02-28Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 085470
application number: ANDA085470
ndc (product): 0009-0271

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
206417Depo-Estradiol 5 MG/ML Injectable SolutionPSN9a4229fd-fecd-4ac1-9c4f-6d442533457f9
310187estradiol cypionate 5 MG/ML Injectable SolutionPSN9a4229fd-fecd-4ac1-9c4f-6d442533457f9
206417estradiol cypionate 5 MG/ML Injectable Solution [Depo-estradiol]SBD9a4229fd-fecd-4ac1-9c4f-6d442533457f9
310187estradiol cypionate 5 MG/ML Injectable SolutionSCD9a4229fd-fecd-4ac1-9c4f-6d442533457f9
206417Depo-Estradiol 5 MG/ML Injectable SolutionSY9a4229fd-fecd-4ac1-9c4f-6d442533457f9

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0009-0271-01000090271011 VIAL in 1 CARTON (0009-0271-01) / 5 mL in 1 VIAL1 vial1979-08-150000-00-00NoNoCurrent