REFRESH OPTIVE

Product NDC: 0023-3240
Requested package NDC: 0023-3240-01
11-digit product format: 000233240
Labeler code: 0023
Product ID: 0023-3240_eb725fdd-160e-4b82-ad29-e54a6cd6f9e4
Type: HUMAN OTC DRUG
Nonproprietary name: carboxymethylcellulose sodium and glycerin
Dosage form: SOLUTION/ DROPS
Route: OPHTHALMIC
Labeler: Allergan, Inc.
Application: M018
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2006-09-06
Substance: CARBOXYMETHYLCELLULOSE SODIUM; GLYCERIN
Active strength: 5; 9 mg/mL; mg/mL
Pharmacologic classes: Allergens [CS], Cell-mediated Immunity [PE], Glycerol [CS], Increased Histamine Release [PE], Increased IgG Production [PE], Non-Standardized Chemical Allergen [EPC]
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

NDC auxiliary status#

Explicit status records from FDA unfinished, excluded, and compounder auxiliary files. Absence of a row is not itself a regulatory status. Browse every current auxiliary row, including rows without a usable NDC. · Browse every captured source and parsed snapshot.

Current NDC status page 1 of 1 · 1 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Source date
excluded package	package	0023-3240	0023-3240-01	D	Discontinued by firm		2026-07-31

openFDA label cross-check#

Cross-check layer: openFDA label JSON enriches search and identifies hydration gaps. The DailyMed Structured Product Label remains the canonical label presentation on FDA.report. Every label matching the complete exact-identifier union is deduplicated and paginated below.

Matched openFDA labels page 1 of 26 · 512 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Neutraflush	EYEWASH STATION ADDITIVE CONCENTRATE	Aero Healthcare	1d9ff2ef-9c9b-f367-e063-6294a90afa0e	2026-07-24	Warnings	Exact identifier application number: M018
Droptics Dry Eye Relief	CARBOXYMETHYLCELLULOSE SODIUM,GLYCERIN,POLYSORBATE 80	Droptics LLC	29d7614b-f4b7-48e2-97c5-d1bff27731d2	2026-07-22	Warnings	Exact identifier application number: M018
GOOD NEIGHBOR PHARMACY ARTIFICAL TEARS LUBRICANT EYE DROPS	POLYVINYL ALCOHOL, POVIDONE	AmerisourceBergen	ce6852a8-c5e6-403d-a7b4-a2e85d1ebb1f	2026-07-22	Warnings	Exact identifier application number: M018
Eyewash Station Additive Concentrate	CHLORHEXIDINE GLUCONATE AND PROPYLENE GLYCOL	Global Equipment Company	bc93a1e8-aa3c-6735-e053-2995a90ad6e8	2026-07-16	Warnings	Exact identifier application number: M018
Revitalize Energizing Eye Drops	NAPHAZOLINE HYDROCHLORIDE ,PROPYLENE GLYCOL	Revitalize Energy Inc.	518aac87-1642-4b2f-bca1-b74d21261eea	2026-07-16	Warnings	Exact identifier application number: M018
Polyvinyl Alcohol	POLYVINYL ALCOHOL	AvPAK	f18b61da-4033-341a-e053-2a95a90a8ebf	2026-07-07	Warnings	Exact identifier application number: M018
Artificial Tears	ARTIFICIAL TEARS	AvPAK	f18bebf2-1936-658f-e053-2a95a90a5012	2026-07-07	Warnings	Exact identifier application number: M018
Retaine CMC	CARBOXYMETHYLCELLULOSE SODIUM	OCuSOFT LLC	a3698c71-0c80-4246-be52-5e7d96f6c540	2026-07-06	Warnings	Exact identifier application number: M018
Eyesaline Eyewash Concentrate	PURIFIED WATER	Protective Industrial Products, Inc.	558e5926-9027-d3f6-e063-6294a90ab121	2026-07-02	Warnings	Exact identifier application number: M018
Fendall 2000 Pure Flow	PURIFIED WATER	Protective Industrial Products, Inc.	55a1d07e-0006-0c75-e063-6394a90a7acc	2026-07-02	Warnings	Exact identifier application number: M018
Fendall 1000 Pure Flow	PURIFIED WATER	Protective Industrial Products, Inc.	55a2f4da-bb1e-8ead-e063-6394a90af72e	2026-07-02	Warnings	Exact identifier application number: M018
Sterile Eyesaline Eyewash	STERILE EYESALINE EYEWASH	Protective Industrial Products, Inc.	55a290e8-8310-8be4-e063-6394a90abdce	2026-07-02	Warnings	Exact identifier application number: M018
Eyesaline Emergency Eyewash	PURIFIED WATER	Protective Industrial Products, Inc.	55a261c2-725d-6765-e063-6294a90a3260	2026-07-02	Warnings	Exact identifier application number: M018
OHTrust Artifical Eyedrop	SODIUM CHLORIDE	Nanoplus Technology Co., Limited	2ea26d96-704b-17bb-e063-6394a90a7e27	2026-07-01	Warnings	Exact identifier application number: M018
Fendall 2000 Pure Flow	PURIFIED WATER	Honeywell Safety Products USA, Inc.	37dead3e-60cb-88ae-e063-6294a90a8f70	2026-06-24	Warnings	Exact identifier application number: M018
Rohto Cool Relief	NAPHAZOLINE HYDROCHLORIDE, POLYSORBATE 80	The Mentholatum Company	dc8f1ff3-87ae-47ca-815f-5a0e34f8cf30	2026-06-19	Warnings	Exact identifier application number: M018
Rohto Sun and Sport	HYPROMELLOSE, POVIDONE	The Mentholatum Company	8bcc8882-b886-4b55-9bc4-d4b92a41358f	2026-06-19	Warnings	Exact identifier application number: M018
Rohto Dual Light Relief	HYPROMELLOSE, POVIDONE	The Mentholatum Company	1b597f83-d7f1-cf93-e063-6394a90a99f7	2026-06-19	Warnings	Exact identifier application number: M018
Lubricant Eye	CARBOXYMETHYLCELLULOSE SODIUM 0.5%	CARDINAL HEALTH 110, LLC. DBA LEADER	51a2d74f-5ff3-9921-e063-6294a90a345a	2026-06-15	Warnings	Exact identifier application number: M018
Lubricant Eye	CARBOXYMETHYLCELLULOSE SODIUM	Rugby Laboratories	51cadca6-a31b-c1b5-e063-6394a90a34d3	2026-06-15	Warnings	Exact identifier application number: M018

Additional Listing Data#

Finished product: Yes
Brand name base: REFRESH OPTIVE
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
CARBOXYMETHYLCELLULOSE SODIUM	5 mg/mL
GLYCERIN	9 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
K679OBS311	Internal UNII lookup
PDC6A3C0OX	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1100650	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
7f8d88af-fd3b-4138-af61-f24c59ccebd7	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
9e37788c-b1bf-42ae-aac9-b60601606144	Product name	8	20260122
30b0ac6e-02aa-0e5c-0d8b-cffdf3a282b2	Product name	5	20250304
1527ac37-808d-43be-a63e-74e1258dbe46	Product name	9	20250219
bed0530e-f939-4541-956b-6928a2f6404f	Product name	1	20241008
cefa60e2-a5b5-493e-9c54-24735b7dc509	Product name	6	20240814
08c722ec-780f-bb7b-8f14-3d4f7bf0e098	Product name	2	20240205
362d7abb-94e6-4c60-9a58-266894157713	Product name	1	20231023
9fcb7a91-de07-4f00-aabf-e4d6fda403d5	Product name	8	20230322
6bd95106-a412-1dad-b9cc-4cb74bfb27ce	Product name	2	20230315
e2f276e5-439f-b432-b5e5-b0cfa993da69	Product name	3	20220609
9badc7be-250a-44ab-aa36-926af3f02679	Product name	1	20210527
0ec3537a-6c9b-432a-896c-b9ea8723049a	Product name	9	20200701
444b3e50-f226-46ef-bfca-2e7035d140cd	Product name	1	20190611
816b97af-edc5-4060-aff1-b814bdbcad50	Product name	1	20190415
7cda52fc-125f-421c-8fea-bc1974370c49	Product name	2	20180703
7916de40-e296-41f0-b811-6d0df1a33e2c	Product name	9	20180627
cefa60e2-a5b5-493e-9c54-24735b7dc509	Product name	2	20171212
419aab54-5d5a-4146-9453-026d4a9991be	Product name	2	20170525
d5e51f11-ad28-caa4-4b49-4143974782ad	Product name	1	20150831
290f523a-f9db-9774-b5a9-e1f908ac1782	Product name	1	20150828
0ca1d589-929b-4b33-bc5b-1d84abdafa6a	Product name	1	20150324
fc363c46-397b-4476-ac0f-70e43e8e4592	Product name	1	20150324
89dac932-b90a-4410-9ab1-84c53e57de25	Product name	1	20150316
4585a4fb-0028-3d95-020c-9b1c40bf15e0	Product name	1	20140508
5668b646-cd56-c3c7-bdea-3f6b1a8840db	Product name	1	20140508
810ab97e-f109-f41c-7c83-6a652a9cbf43	Product name	1	20140508
87711080-88eb-65c5-b2dd-bf99e700a372	Product name	1	20140508
8dbefedf-0a0d-a224-5a3c-66dc9e11c2dd	Product name	1	20140508
c6b65c52-69c7-df49-550a-a50c137f6218	Product name	1	20140508
ec2149b3-5c6d-5344-f757-c86411073075	Product name	1	20140508
ed912195-5da0-0f2f-6f4b-3ef17710cbe3	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
0023-3240-01	REFRESH OPTIVE	2 in 1 CARTON	SOLUTION/ DROPS	2	12
0023-3240-01	REFRESH OPTIVE	15 mL in 1 BOTTLE, DROPPER	SOLUTION/ DROPS	15	12
0023-3240-02	REFRESH OPTIVE	1 in 1 CARTON	SOLUTION/ DROPS	1	12
0023-3240-02	REFRESH OPTIVE	2 mL in 1 BOTTLE, DROPPER	SOLUTION/ DROPS	2	12
0023-3240-03	REFRESH OPTIVE	1 in 1 CARTON	SOLUTION/ DROPS	1	12
0023-3240-03	REFRESH OPTIVE	3 mL in 1 BOTTLE, DROPPER	SOLUTION/ DROPS	3	12
0023-3240-15	REFRESH OPTIVE	1 in 1 CARTON	SOLUTION/ DROPS	1	12
0023-3240-15	REFRESH OPTIVE	15 mL in 1 BOTTLE, DROPPER	SOLUTION/ DROPS	15	12

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
0023-3240-01	ML - Milliliter	0023-3240	c28ae2fd-afee-4515-806c-686431e7e3c2	1	2012-07-24
0023-3240-10	ML - Milliliter	0023-3240	6eb0523b-0945-4574-bae9-e913626b5bf7	1	2012-07-24
0023-3240-15	ML - Milliliter	0023-3240	1ea253fb-4ecc-49c4-9ec1-22b7b4ec10a5	1	2012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
carboxymethylcellulose sodium	ACTIVE INGREDIENT	K679OBS311	REFRESH OPTIVE (CARBOXYMETHYLCELLULOSE SODIUM AND GLYCERIN) SOLUTION/ DROPS [ALLERGAN, INC.]	5
glycerin	ACTIVE INGREDIENT	PDC6A3C0OX	REFRESH OPTIVE (CARBOXYMETHYLCELLULOSE SODIUM AND GLYCERIN) SOLUTION/ DROPS [ALLERGAN, INC.]	5
carboxymethylcellulose	ACTIVE MOIETY	05JZI7B19X	REFRESH OPTIVE (CARBOXYMETHYLCELLULOSE SODIUM AND GLYCERIN) SOLUTION/ DROPS [ALLERGAN, INC.]	5
glycerin	ACTIVE MOIETY	PDC6A3C0OX	REFRESH OPTIVE (CARBOXYMETHYLCELLULOSE SODIUM AND GLYCERIN) SOLUTION/ DROPS [ALLERGAN, INC.]	5
boric acid	INACTIVE INGREDIENT	R57ZHV85D4	REFRESH OPTIVE (CARBOXYMETHYLCELLULOSE SODIUM AND GLYCERIN) SOLUTION/ DROPS [ALLERGAN, INC.]	5
calcium chloride	INACTIVE INGREDIENT	M4I0D6VV5M	REFRESH OPTIVE (CARBOXYMETHYLCELLULOSE SODIUM AND GLYCERIN) SOLUTION/ DROPS [ALLERGAN, INC.]	5
chlorine dioxide	INACTIVE INGREDIENT	8061YMS4RM	REFRESH OPTIVE (CARBOXYMETHYLCELLULOSE SODIUM AND GLYCERIN) SOLUTION/ DROPS [ALLERGAN, INC.]	5
erythritol	INACTIVE INGREDIENT	RA96B954X6	REFRESH OPTIVE (CARBOXYMETHYLCELLULOSE SODIUM AND GLYCERIN) SOLUTION/ DROPS [ALLERGAN, INC.]	5
levocarnitine	INACTIVE INGREDIENT	0G389FZZ9M	REFRESH OPTIVE (CARBOXYMETHYLCELLULOSE SODIUM AND GLYCERIN) SOLUTION/ DROPS [ALLERGAN, INC.]	5
magnesium chloride	INACTIVE INGREDIENT	02F3473H9O	REFRESH OPTIVE (CARBOXYMETHYLCELLULOSE SODIUM AND GLYCERIN) SOLUTION/ DROPS [ALLERGAN, INC.]	5
potassium chloride	INACTIVE INGREDIENT	660YQ98I10	REFRESH OPTIVE (CARBOXYMETHYLCELLULOSE SODIUM AND GLYCERIN) SOLUTION/ DROPS [ALLERGAN, INC.]	5
sodium borate	INACTIVE INGREDIENT	91MBZ8H3QO	REFRESH OPTIVE (CARBOXYMETHYLCELLULOSE SODIUM AND GLYCERIN) SOLUTION/ DROPS [ALLERGAN, INC.]	5
sodium chlorate	INACTIVE INGREDIENT	T95DR77GMR	REFRESH OPTIVE (CARBOXYMETHYLCELLULOSE SODIUM AND GLYCERIN) SOLUTION/ DROPS [ALLERGAN, INC.]	5
sodium chlorite	INACTIVE INGREDIENT	G538EBV4VF	REFRESH OPTIVE (CARBOXYMETHYLCELLULOSE SODIUM AND GLYCERIN) SOLUTION/ DROPS [ALLERGAN, INC.]	5
trisodium citrate dihydrate	INACTIVE INGREDIENT	B22547B95K	REFRESH OPTIVE (CARBOXYMETHYLCELLULOSE SODIUM AND GLYCERIN) SOLUTION/ DROPS [ALLERGAN, INC.]	5
water	INACTIVE INGREDIENT	059QF0KO0R	REFRESH OPTIVE (CARBOXYMETHYLCELLULOSE SODIUM AND GLYCERIN) SOLUTION/ DROPS [ALLERGAN, INC.]	5

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
0023-3240	REFRESH OPTIVE (CARBOXYMETHYLCELLULOSE SODIUM AND GLYCERIN) SOLUTION/ DROPS [ALLERGAN, INC.]	12	Current NDC, Legacy NDC, 8 package rows	20240929_7f8d88af-fd3b-4138-af61-f24c59ccebd7.zip

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
PDC6A3C0OX	GLYCERIN	56-81-5	GLYCERIN

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1100650	carboxymethylcellulose sodium 0.5 % / glycerin 0.9 % Ophthalmic Solution	PSN	7f8d88af-fd3b-4138-af61-f24c59ccebd7	12
1100650	carboxymethylcellulose sodium 5 MG/ML / glycerin 9 MG/ML Ophthalmic Solution	SCD	7f8d88af-fd3b-4138-af61-f24c59ccebd7	12
1100650	carboxymethylcellulose sodium 0.5 % / glycerin 0.9 % Ophthalmic Solution	SY	7f8d88af-fd3b-4138-af61-f24c59ccebd7	12

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Marketing start	Marketing end	Sample	Exclude flag	Status
0023-3240-01	00023324001	2 BOTTLE, DROPPER in 1 CARTON (0023-3240-01) > 15 mL in 1 BOTTLE, DROPPER	2006-09-06	0000-00-00	No	No	Current