Promethazine VC

Product NDC
0121-0926
Requested package NDC
0121-0926-16
11-digit product format
001210926
Labeler code
0121
Product ID
0121-0926_bd449be1-5e7f-35a8-e053-2995a90a2e02
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Promethazine Hydrochloride and Phenylephrine Hydrochloride
Dosage form
SOLUTION
Route
ORAL
Labeler
Pharmaceutical Associates, Inc.
Application
ANDA040654
Marketing category
ANDA
Marketing start
2021-03-11
Marketing end
0000-00-00
Substance
PROMETHAZINE HYDROCHLORIDE; PHENYLEPHRINE HYDROCHLORIDE
Active strength
6 mg/5mL; mg/5mL
Pharmacologic classes
Phenothiazine [EPC],Phenothiazines [CS],alpha-1 Adrenergic Agonist [EPC],Adrenergic alpha1-Agonists [MoA]
NDC exclude flag
No
Listing certified through
2022-12-31
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 1 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded packagepackage0121-09260121-0926-16DDiscontinued by firm2026-08-03

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 2 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source dateDatasetScopeProduct NDCPackage NDCCodeStatusReporting periodArchiveSnapshotSource SHA-256
2025-12-14 17:58 UTC · source 2025-12-05excluded packagepackage0121-09260121-0926-16DDiscontinued by firmexcluded / ndc_excluded.zipd630ba8d3edf…732f749b63fb…
2025-08-27 00:01 UTC · source 2025-08-26excluded packagepackage0121-09260121-0926-16DDiscontinued by firmexcluded / ndc_excluded.zipf5e01cc5f278…a2eaf40c39c3…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDEPHENYLEPHRINE HYDROCHLORIDE; PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-07

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A040654-001AA

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-07011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-0731067a03dcf5…
2025-08-23 18:47 UTC2025-08A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-076a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-07fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-07b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-0703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-072680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-075bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-07d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-07d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-0779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-07301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-071e350fbaab3a…
2024-05-31 18:47 UTC2024-05A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-078072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-075c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-075d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-074b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-0774a2ff9319b5…
2022-03-09 01:35 UTC2022-03A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-07bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-07782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-0787673890dc5c…
2021-03-12 10:30 UTC2021-03A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-075aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-078869cabd3fbd…
2020-11-12 02:37 UTC2020-11A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-07c0c555d07b60…
2019-12-14 00:12 UTC2019-12A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-073f01610625f2…
2019-09-15 20:21 UTC2019-09A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-07b00525d2431f…
2019-07-19 19:46 UTC2019-07A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-07ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-076a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-071c564ffb4f44…
2023-12-20 04:57 UTC2023-12A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-07ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-07a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-079b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-07a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-073f0d92c62455…
2023-05-13 08:27 UTC2023-05A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-07053a50430f4f…
2023-01-26 05:58 UTC2023-01A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-073bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-073a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-07f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-07e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A040654-001PHENYLEPHRINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE5MG/5ML;6.25MG/5MLSYRUP / ORALAARS2006-12-07cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A040654-001AA1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A040654-001AA131067a03dcf5…
2025-08-23 18:47 UTC2025-08A040654-001AA16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A040654-001AA1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A040654-001AA1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A040654-001AA103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A040654-001AA12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A040654-001AA15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A040654-001AA1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A040654-001AA1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A040654-001AA179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A040654-001AA1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A040654-001AA11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A040654-001AA18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A040654-001AA15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A040654-001AA15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A040654-001AA14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A040654-001AA174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A040654-001AA1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A040654-001AA1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A040654-001AA187673890dc5c…
2021-03-12 10:30 UTC2021-03A040654-001AA15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A040654-001AA18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A040654-001AA1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A040654-001AA13f01610625f2…
2019-09-15 20:21 UTC2019-09A040654-001AA1b00525d2431f…
2019-07-19 19:46 UTC2019-07A040654-001AA1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A040654-001AA16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A040654-001AA11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A040654-001AA1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A040654-001AA1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A040654-001AA19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A040654-001AA1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A040654-001AA13f0d92c62455…
2023-05-13 08:27 UTC2023-05A040654-001AA1053a50430f4f…
2023-01-26 05:58 UTC2023-01A040654-001AA13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A040654-001AA13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A040654-001AA1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A040654-001AA1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A040654-001AA1cb3db0bc1861…

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0121-0926-16ML - Milliliter0121-09268bf8ba20-b8a6-457e-8e99-e9e9a1f542a212021-04-08

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Promethazine Hydrochloride and Phenylephrine HydrochloridePROMETHAZINE HYDROCHLORIDE AND PHENYLEPHRINE HYDROCHLORIDEGenus Lifesciences Inc.7f8ebc9c-c4e6-4344-95a5-ec25b8c99bc12024-07-22Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 040654
application number: ANDA040654

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0121-0926-1600121092616437 mL in 1 BOTTLE (0121-0926-16) 437 ml2021-03-110000-00-00NoNoCurrent