Tacrolimus

Product NDC
0168-0417
Requested package NDC
0168-0417-99
11-digit product format
001680417
Labeler code
0168
Product ID
0168-0417_a63cc4f4-5aba-4e02-915a-5535f2b625aa
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
tacrolimus
Dosage form
OINTMENT
Route
TOPICAL
Labeler
E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC
Application
ANDA200744
Marketing category
ANDA
Marketing start
2014-09-09
Substance
TACROLIMUS
Active strength
.3 mg/g
Pharmacologic classes
Calcineurin Inhibitor Immunosuppressant [EPC], Calcineurin Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A200744-001TACROLIMUSTACROLIMUS0.03%OINTMENT / TOPICALAB2014-09-09
A200744-002TACROLIMUSTACROLIMUS0.1%OINTMENT / TOPICALAB2014-09-09

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A200744-001AB
A200744-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A200744-001TACROLIMUS0.03%OINTMENT / TOPICALAB2014-09-09011fe1cb6892…
2026-02-19 14:30 UTC2026-02A200744-002TACROLIMUS0.1%OINTMENT / TOPICALAB2014-09-09011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A200744-001TACROLIMUS0.03%OINTMENT / TOPICALAB2014-09-0931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A200744-002TACROLIMUS0.1%OINTMENT / TOPICALAB2014-09-0931067a03dcf5…
2025-08-23 18:47 UTC2025-08A200744-001TACROLIMUS0.03%OINTMENT / TOPICALAB2014-09-096a471c1ec25d…
2025-08-23 18:47 UTC2025-08A200744-002TACROLIMUS0.1%OINTMENT / TOPICALAB2014-09-096a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A200744-001TACROLIMUS0.03%OINTMENT / TOPICALAB2014-09-09fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A200744-002TACROLIMUS0.1%OINTMENT / TOPICALAB2014-09-09fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A200744-001TACROLIMUS0.03%OINTMENT / TOPICALAB2014-09-09b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A200744-002TACROLIMUS0.1%OINTMENT / TOPICALAB2014-09-09b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A200744-001TACROLIMUS0.03%OINTMENT / TOPICALAB2014-09-0903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A200744-002TACROLIMUS0.1%OINTMENT / TOPICALAB2014-09-0903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A200744-001TACROLIMUS0.03%OINTMENT / TOPICALAB2014-09-092680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A200744-002TACROLIMUS0.1%OINTMENT / TOPICALAB2014-09-092680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A200744-001TACROLIMUS0.03%OINTMENT / TOPICALAB2014-09-095bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A200744-002TACROLIMUS0.1%OINTMENT / TOPICALAB2014-09-095bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A200744-001TACROLIMUS0.03%OINTMENT / TOPICALAB2014-09-09d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A200744-002TACROLIMUS0.1%OINTMENT / TOPICALAB2014-09-09d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A200744-001TACROLIMUS0.03%OINTMENT / TOPICALAB2014-09-09d06236e962d9…
2024-10-29 15:01 UTC2024-10A200744-002TACROLIMUS0.1%OINTMENT / TOPICALAB2014-09-09d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A200744-001TACROLIMUS0.03%OINTMENT / TOPICALAB2014-09-0979d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A200744-002TACROLIMUS0.1%OINTMENT / TOPICALAB2014-09-0979d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A200744-001TACROLIMUS0.03%OINTMENT / TOPICALAB2014-09-09301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A200744-002TACROLIMUS0.1%OINTMENT / TOPICALAB2014-09-09301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A200744-001TACROLIMUS0.03%OINTMENT / TOPICALAB2014-09-091e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A200744-002TACROLIMUS0.1%OINTMENT / TOPICALAB2014-09-091e350fbaab3a…
2024-05-31 18:47 UTC2024-05A200744-001TACROLIMUS0.03%OINTMENT / TOPICALAB2014-09-098072bd15b7f6…
2024-05-31 18:47 UTC2024-05A200744-002TACROLIMUS0.1%OINTMENT / TOPICALAB2014-09-098072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A200744-001TACROLIMUS0.03%OINTMENT / TOPICALAB2014-09-095c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A200744-002TACROLIMUS0.1%OINTMENT / TOPICALAB2014-09-095c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A200744-001TACROLIMUS0.03%OINTMENT / TOPICALAB2014-09-095d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A200744-002TACROLIMUS0.1%OINTMENT / TOPICALAB2014-09-095d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A200744-001TACROLIMUS0.03%OINTMENT / TOPICALAB2014-09-094b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A200744-002TACROLIMUS0.1%OINTMENT / TOPICALAB2014-09-094b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A200744-001TACROLIMUS0.03%OINTMENT / TOPICALAB2014-09-0974a2ff9319b5…
2019-12-13 00:20 UTC2019-12A200744-002TACROLIMUS0.1%OINTMENT / TOPICALAB2014-09-0974a2ff9319b5…
2022-03-09 01:35 UTC2022-03A200744-001TACROLIMUS0.03%OINTMENT / TOPICALAB2014-09-09bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A200744-002TACROLIMUS0.1%OINTMENT / TOPICALAB2014-09-09bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A200744-001TACROLIMUS0.03%OINTMENT / TOPICALAB2014-09-09782e0a99824c…
2021-12-28 21:50 UTC2021-12A200744-002TACROLIMUS0.1%OINTMENT / TOPICALAB2014-09-09782e0a99824c…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A200744-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A200744-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A200744-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A200744-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A200744-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A200744-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A200744-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A200744-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A200744-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A200744-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A200744-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A200744-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A200744-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A200744-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A200744-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A200744-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A200744-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A200744-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A200744-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A200744-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A200744-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A200744-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A200744-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A200744-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A200744-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A200744-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A200744-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A200744-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A200744-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A200744-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A200744-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A200744-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A200744-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A200744-002AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A200744-001AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A200744-002AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A200744-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A200744-002AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A200744-001AB1782e0a99824c…
2021-12-28 21:50 UTC2021-12A200744-002AB1782e0a99824c…

Additional Listing Data#

Finished product
Yes
Brand name base
Tacrolimus
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
TACROLIMUS.3 mg/g

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
WM0HAQ4WNMInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
313189Internal RxNorm lookup
314266Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1bf44a84-14fd-4f80-ad8a-99b1431d631fAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
df369ad4-19d8-393a-de46-8c6255b8b360Product name820251120
d2a74186-7b26-dbcc-9435-50b3d0be14abProduct name220250114
a64835ae-fa9d-41d8-9a93-36828ba72b96Product name320190611
b4a869e4-9fcd-47bd-95e3-85e7c75f8badProduct name120150819

FDA-Initiated Inactive NDC Indexing#

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0168-0417-30Tacrolimus30 g in 1 TUBEOINTMENT3013
0168-0417-30Tacrolimus1 in 1 CARTONOINTMENT113
0168-0417-60Tacrolimus1 in 1 CARTONOINTMENT113
0168-0417-60Tacrolimus60 g in 1 TUBEOINTMENT6013
0168-0417-99Tacrolimus100 g in 1 TUBEOINTMENT10013
0168-0417-99Tacrolimus1 in 1 CARTONOINTMENT113

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0168-0417-30GM - Gram0168-0417489b6f0d-9a25-4304-846d-7a2d8e4776f112014-12-01
0168-0417-60GM - Gram0168-041721d9dbe7-9460-41be-9ba6-095f870a822312014-12-01
0168-0417-99GM - Gram0168-04173e2c3502-8966-4676-8d7c-197c00a88bff12014-12-01

DailyMed Socrata Ingredients#

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0168-0417TACROLIMUS OINTMENT [E. FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC.]12Current NDC, Legacy NDC, 6 package rows20231102_1bf44a84-14fd-4f80-ad8a-99b1431d631f.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
TacrolimusTACROLIMUSE. Fougera & Co. a division of Fougera Pharmaceuticals, LLC1bf44a84-14fd-4f80-ad8a-99b1431d631f2026-01-28Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 200744
application number: ANDA200744
ndc (package): 0168-0417-99
ndc (product): 0168-0417
ndc11 (package): 00168041799

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
313189tacrolimus 0.03 % Topical OintmentPSN1bf44a84-14fd-4f80-ad8a-99b1431d631f13
314266tacrolimus 0.1 % Topical OintmentPSN1bf44a84-14fd-4f80-ad8a-99b1431d631f13
313189tacrolimus 0.0003 MG/MG Topical OintmentSCD1bf44a84-14fd-4f80-ad8a-99b1431d631f13
314266tacrolimus 0.001 MG/MG Topical OintmentSCD1bf44a84-14fd-4f80-ad8a-99b1431d631f13
313189tacrolimus (as tacrolimus monohydrate) 0.0003 MG/MG Topical OintmentSY1bf44a84-14fd-4f80-ad8a-99b1431d631f13
314266tacrolimus (as tacrolimus monohydrate) 0.001 MG/MG Topical OintmentSY1bf44a84-14fd-4f80-ad8a-99b1431d631f13
313189tacrolimus 0.03 % Topical OintmentSY1bf44a84-14fd-4f80-ad8a-99b1431d631f13
314266tacrolimus 0.1 % Topical OintmentSY1bf44a84-14fd-4f80-ad8a-99b1431d631f13

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0168-0417-99001680417991 TUBE in 1 CARTON (0168-0417-99) / 100 g in 1 TUBE1 tube2014-09-090000-00-00NoNoCurrent