IRESSA

Product NDC
0310-0482
11-digit product format
003100482
Labeler code
0310
Product ID
0310-0482_508019dd-61d5-4459-9476-3f5897143f0c
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Gefitinib
Dosage form
TABLET, COATED
Route
ORAL
Labeler
AstraZeneca Pharmaceuticals LP
Application
NDA206995
Marketing category
NDA
Marketing start
2015-07-13
Substance
GEFITINIB
Active strength
250 mg/1
Pharmacologic classes
Kinase Inhibitor [EPC], Protein Kinase Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 1 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded packagepackage0310-04820310-0482-93DDiscontinued by firm2026-08-03

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 12 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Snapshot, Source SHA-256 table
Captured / source dateSnapshotSource SHA-256
2025-12-14 17:58 UTC · source 2025-12-05d630ba8d3edf…732f749b63fb…
2025-08-27 00:01 UTC · source 2025-08-26f5e01cc5f278…a2eaf40c39c3…
2025-04-01 02:39 UTC · source 2025-03-312ef7874e63bc…57b86245f4fa…
2025-03-28 20:22 UTC · source 2025-03-28a1b67e2a42f9…c4cf2c586c0d…
2025-03-22 03:12 UTC · source 2025-03-21cfe11265f3b6…090c488252e2…
2025-03-10 12:48 UTC · source 2025-03-10cdf11ea48f46…ba0047e9e063…
2025-02-02 03:52 UTC · source 2025-01-31302b2466d912…e7b80fea0513…
2025-01-20 13:05 UTC · source 2025-01-20ed331223b511…672a5bd82f5f…
2025-01-11 03:41 UTC · source 2025-01-100efc9e666f02…f202fb6c5f17…
2024-11-09 02:27 UTC · source 2024-11-08ad56d346431e…cc804d4bbf1e…
2024-10-04 04:10 UTC · source 2024-10-03367a005e9d99…383a685ebd0f…
2024-07-10 04:00 UTC · source 2024-07-09557ba5c1ecfa…9c80585c8c6e…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N206995-001IRESSAGEFITINIB250MGTABLET / ORALABRLD, RS2015-07-13

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
N206995-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N206995-001IRESSA250MGTABLET / ORALABRLD, RS2015-07-13011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N206995-001IRESSA250MGTABLET / ORALABRLD, RS2015-07-1331067a03dcf5…
2025-08-23 18:47 UTC2025-08N206995-001IRESSA250MGTABLET / ORALABRLD, RS2015-07-136a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N206995-001IRESSA250MGTABLET / ORALABRLD, RS2015-07-13fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N206995-001IRESSA250MGTABLET / ORALABRLD, RS2015-07-13b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N206995-001IRESSA250MGTABLET / ORALABRLD, RS2015-07-1303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N206995-001IRESSA250MGTABLET / ORALABRLD, RS2015-07-132680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N206995-001IRESSA250MGTABLET / ORALABRLD, RS2015-07-135bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N206995-001IRESSA250MGTABLET / ORALABRLD, RS2015-07-13d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N206995-001IRESSA250MGTABLET / ORALABRLD, RS2015-07-13d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N206995-001IRESSA250MGTABLET / ORALABRLD, RS2015-07-1379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N206995-001IRESSA250MGTABLET / ORALABRLD, RS2015-07-13301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N206995-001IRESSA250MGTABLET / ORALABRLD, RS2015-07-131e350fbaab3a…
2024-05-31 18:47 UTC2024-05N206995-001IRESSA250MGTABLET / ORALABRLD, RS2015-07-138072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N206995-001IRESSA250MGTABLET / ORALRLD, RS2015-07-135c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N206995-001IRESSA250MGTABLET / ORALRLD, RS2015-07-135d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N206995-001IRESSA250MGTABLET / ORALRLD, RS2015-07-134b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N206995-001IRESSA250MGTABLET / ORALRLD, RS2015-07-1374a2ff9319b5…
2022-03-09 01:35 UTC2022-03N206995-001IRESSA250MGTABLET / ORALRLD, RS2015-07-13bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N206995-001IRESSA250MGTABLET / ORALRLD, RS2015-07-13782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N206995-001IRESSA250MGTABLET / ORALRLD, RS2015-07-1387673890dc5c…
2021-03-12 10:30 UTC2021-03N206995-001IRESSA250MGTABLET / ORALRLD, RS2015-07-135aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N206995-001IRESSA250MGTABLET / ORALRLD, RS2015-07-138869cabd3fbd…
2020-11-12 02:37 UTC2020-11N206995-001IRESSA250MGTABLET / ORALRLD, RS2015-07-13c0c555d07b60…
2019-12-14 00:12 UTC2019-12N206995-001IRESSA250MGTABLET / ORALRLD, RS2015-07-133f01610625f2…
2019-09-15 20:21 UTC2019-09N206995-001IRESSA250MGTABLET / ORALRLD, RS2015-07-13b00525d2431f…
2019-07-19 19:46 UTC2019-07N206995-001IRESSA250MGTABLET / ORALRLD, RS2015-07-13ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N206995-001IRESSA250MGTABLET / ORALABRLD, RS2015-07-136a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N206995-001IRESSA250MGTABLET / ORALABRLD, RS2015-07-131c564ffb4f44…
2023-12-20 04:57 UTC2023-12N206995-001IRESSA250MGTABLET / ORALABRLD, RS2015-07-13ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N206995-001IRESSA250MGTABLET / ORALABRLD, RS2015-07-13a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N206995-001IRESSA250MGTABLET / ORALABRLD, RS2015-07-139b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N206995-001IRESSA250MGTABLET / ORALABRLD, RS2015-07-13a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N206995-001IRESSA250MGTABLET / ORALABRLD, RS2015-07-133f0d92c62455…
2023-05-13 08:27 UTC2023-05N206995-001IRESSA250MGTABLET / ORALABRLD, RS2015-07-13053a50430f4f…
2023-01-26 05:58 UTC2023-01N206995-001IRESSA250MGTABLET / ORALABRLD, RS2015-07-133bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N206995-001IRESSA250MGTABLET / ORALABRLD, RS2015-07-133a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N206995-001IRESSA250MGTABLET / ORALABRLD, RS2015-07-13f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N206995-001IRESSA250MGTABLET / ORALRLD, RS2015-07-13e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N206995-001IRESSA250MGTABLET / ORALRLD, RS2015-07-13cb3db0bc1861…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N206995-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N206995-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N206995-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N206995-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N206995-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N206995-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N206995-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N206995-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N206995-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N206995-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N206995-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N206995-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N206995-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N206995-001AB18072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N206995-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N206995-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12N206995-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N206995-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N206995-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N206995-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N206995-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05N206995-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01N206995-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N206995-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N206995-001AB1f41ea6bd6efb…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N206995-001AB1a50c72e98297…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N206995-001ODE-952022-07-135c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N206995-001ODE-952022-07-135d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N206995-001ODE-952022-07-134b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N206995-001ODE-952022-07-1374a2ff9319b5…
2022-03-09 01:35 UTC2022-03N206995-001ODE-952022-07-13bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N206995-001ODE-952022-07-13782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N206995-001ODE-952022-07-1387673890dc5c…
2021-03-12 10:30 UTC2021-03N206995-001ODE-952022-07-135aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N206995-001ODE-952022-07-138869cabd3fbd…
2020-11-12 02:37 UTC2020-11N206995-001ODE-952022-07-13c0c555d07b60…
2019-12-14 00:12 UTC2019-12N206995-001ODE-952022-07-133f01610625f2…
2019-09-15 20:21 UTC2019-09N206995-001ODE-952022-07-13b00525d2431f…
2019-07-19 19:46 UTC2019-07N206995-001ODE-952022-07-13ea99ee380514…
2023-01-26 05:58 UTC2023-01N206995-001ODE-952022-07-133bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N206995-001ODE-952022-07-133a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N206995-001ODE-952022-07-13f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N206995-001ODE-952022-07-13e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N206995-001ODE-952022-07-13cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
IRESSA
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
GEFITINIB250 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
S65743JHBSInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
349472Internal RxNorm lookup
402091Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
827d60e8-7e07-41b7-c28b-49ef1c4a5a41Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
15910139-bf2a-487e-8f21-64569f704efcProduct name320260304

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0310-0482-30IRESSA30 in 1 BOTTLETABLET, COATED3019
0310-0482-93IRESSA30 in 1 BOTTLETABLET, COATED3019

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0310-0482-30EA - Each0310-0482b0fff58f-d034-4cc6-9b22-2f98c19441ef12012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
GEFITINIBACTIVE INGREDIENTS65743JHBSIRESSA (GEFITINIB) TABLET, COATED [ASTRAZENECA PHARMACEUTICALS LP]8
GEFITINIBACTIVE MOIETYS65743JHBSIRESSA (GEFITINIB) TABLET, COATED [ASTRAZENECA PHARMACEUTICALS LP]8
CELLULOSE, MICROCRYSTALLINEINACTIVE INGREDIENTOP1R32D61UIRESSA (GEFITINIB) TABLET, COATED [ASTRAZENECA PHARMACEUTICALS LP]8
CROSCARMELLOSE SODIUMINACTIVE INGREDIENTM28OL1HH48IRESSA (GEFITINIB) TABLET, COATED [ASTRAZENECA PHARMACEUTICALS LP]8
FERRIC OXIDE REDINACTIVE INGREDIENT1K09F3G675IRESSA (GEFITINIB) TABLET, COATED [ASTRAZENECA PHARMACEUTICALS LP]8
FERRIC OXIDE YELLOWINACTIVE INGREDIENTEX438O2MRTIRESSA (GEFITINIB) TABLET, COATED [ASTRAZENECA PHARMACEUTICALS LP]8
HYPROMELLOSESINACTIVE INGREDIENT3NXW29V3WOIRESSA (GEFITINIB) TABLET, COATED [ASTRAZENECA PHARMACEUTICALS LP]8
LACTOSE MONOHYDRATEINACTIVE INGREDIENTEWQ57Q8I5XIRESSA (GEFITINIB) TABLET, COATED [ASTRAZENECA PHARMACEUTICALS LP]8
MAGNESIUM STEARATEINACTIVE INGREDIENT70097M6I30IRESSA (GEFITINIB) TABLET, COATED [ASTRAZENECA PHARMACEUTICALS LP]8
POLYETHYLENE GLYCOL 300INACTIVE INGREDIENT5655G9Y8AQIRESSA (GEFITINIB) TABLET, COATED [ASTRAZENECA PHARMACEUTICALS LP]8
POVIDONESINACTIVE INGREDIENTFZ989GH94EIRESSA (GEFITINIB) TABLET, COATED [ASTRAZENECA PHARMACEUTICALS LP]8
SODIUM LAURYL SULFATEINACTIVE INGREDIENT368GB5141JIRESSA (GEFITINIB) TABLET, COATED [ASTRAZENECA PHARMACEUTICALS LP]8
TITANIUM DIOXIDEINACTIVE INGREDIENT15FIX9V2JPIRESSA (GEFITINIB) TABLET, COATED [ASTRAZENECA PHARMACEUTICALS LP]8

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0310-0482IRESSA (GEFITINIB) TABLET, COATED [ASTRAZENECA PHARMACEUTICALS LP]18Current NDC, Legacy NDC, 2 package rows20240517_827d60e8-7e07-41b7-c28b-49ef1c4a5a41.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
IRESSAGEFITINIBAstraZeneca Pharmaceuticals LP827d60e8-7e07-41b7-c28b-49ef1c4a5a412023-02-28Warnings, Adverse reactionsExact identifier
application applno (NDA): 206995
application number: NDA206995
ndc (product): 0310-0482

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
349472gefitinib 250 MG Oral TabletPSN827d60e8-7e07-41b7-c28b-49ef1c4a5a4119
402091Iressa 250 MG Oral TabletPSN827d60e8-7e07-41b7-c28b-49ef1c4a5a4119
402091gefitinib 250 MG Oral Tablet [Iressa]SBD827d60e8-7e07-41b7-c28b-49ef1c4a5a4119
349472gefitinib 250 MG Oral TabletSCD827d60e8-7e07-41b7-c28b-49ef1c4a5a4119
402091Iressa 250 MG Oral TabletSY827d60e8-7e07-41b7-c28b-49ef1c4a5a4119

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
0310-0482-300031004823030 TABLET, COATED in 1 BOTTLE (0310-0482-30) 2015-07-130000-00-00NoNoCurrent
0310-0482-930031004829330 in 1 BOTTLEHistorical