Home NDC 0573-0190-20 Advil Multi-Symptom Cold and Flu
Product NDC 0573-0190
Requested package NDC 0573-0190-20
11-digit product format 005730190
Labeler code 0573
Product ID 0573-0190_4042cf07-a239-1ae9-e063-6394a90acd01
Type HUMAN OTC DRUG
Nonproprietary name chlorpheniramine maleate, ibuprofen, phenylephrine HCl
Dosage form TABLET, COATED
Route ORAL
Labeler Haleon US Holdings LLC
Application NDA022113
Marketing category NDA
Marketing start 2018-06-25
Substance CHLORPHENIRAMINE MALEATE; IBUPROFEN; PHENYLEPHRINE HYDROCHLORIDE
Active strength 4; 200; 10 mg/1; mg/1; mg/1
Pharmacologic classes Adrenergic alpha1-Agonists [MoA], Anti-Inflammatory Agents, Non-Steroidal [CS], Cyclooxygenase Inhibitors [MoA], Histamine H1 Receptor Antagonists [MoA], Histamine-1 Receptor Antagonist [EPC], Nonsteroidal Anti-inflammatory Drug [EPC], alpha-1 Adrenergic Agonist [EPC]
NDC exclude flag No
Listing certified through 2026-12-31
Current FDA listing Yes Source provenance: Browse the complete Orange Book source catalog · source snapshot 1 .
Orange Book products# Current product rows page 1 of 1 · 2 matching rows.
Application-product, Trade name, Ingredient table Application-product Trade name Ingredient Strength Dosage form / route TE codes RLD / RS Approval date N022113-001 ADVIL ALLERGY AND CONGESTION RELIEF CHLORPHENIRAMINE MALEATE; IBUPROFEN; PHENYLEPHRINE HYDROCHLORIDE 4MG;200MG;10MG TABLET / ORAL RLD, RS 2011-12-21 N022113-002 ADVIL MULTI-SYMPTOM COLD & FLU CHLORPHENIRAMINE MALEATE; IBUPROFEN; PHENYLEPHRINE HYDROCHLORIDE 4MG;200MG;10MG TABLET / ORAL RLD, RS 2017-04-28
Observed Orange Book product history# Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.
Product history page 1 of 3 · 82 observed states.
Captured, Edition, Application-product table Captured Edition Application-product Trade name Strength Dosage form / route Product TE source text RLD / RS Approval date Source SHA-256 2026-02-19 14:30 UTC 2026-02 N022113-001 ADVIL ALLERGY AND CONGESTION RELIEF 4MG;200MG;10MG TABLET / ORAL RLD, RS 2011-12-21 011fe1cb6892…2026-02-19 14:30 UTC 2026-02 N022113-002 ADVIL MULTI-SYMPTOM COLD & FLU 4MG;200MG;10MG TABLET / ORAL RLD, RS 2017-04-28 011fe1cb6892…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N022113-001 ADVIL ALLERGY AND CONGESTION RELIEF 4MG;200MG;10MG TABLET / ORAL RLD, RS 2011-12-21 31067a03dcf5…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N022113-002 ADVIL MULTI-SYMPTOM COLD & FLU 4MG;200MG;10MG TABLET / ORAL RLD, RS 2017-04-28 31067a03dcf5…2025-08-23 18:47 UTC 2025-08 N022113-001 ADVIL ALLERGY AND CONGESTION RELIEF 4MG;200MG;10MG TABLET / ORAL RLD, RS 2011-12-21 6a471c1ec25d…2025-08-23 18:47 UTC 2025-08 N022113-002 ADVIL MULTI-SYMPTOM COLD & FLU 4MG;200MG;10MG TABLET / ORAL RLD, RS 2017-04-28 6a471c1ec25d…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 N022113-001 ADVIL ALLERGY AND CONGESTION RELIEF 4MG;200MG;10MG TABLET / ORAL RLD, RS 2011-12-21 fd3edfee7708…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 N022113-002 ADVIL MULTI-SYMPTOM COLD & FLU 4MG;200MG;10MG TABLET / ORAL RLD, RS 2017-04-28 fd3edfee7708…2025-02-26 10:13 UTC · 3 captures of this ZIP 2025-02 N022113-001 ADVIL ALLERGY AND CONGESTION RELIEF 4MG;200MG;10MG TABLET / ORAL RLD, RS 2011-12-21 b8a1b40f171c…2025-02-26 10:13 UTC · 3 captures of this ZIP 2025-02 N022113-002 ADVIL MULTI-SYMPTOM COLD & FLU 4MG;200MG;10MG TABLET / ORAL RLD, RS 2017-04-28 b8a1b40f171c…2025-01-19 17:59 UTC · 7 captures of this ZIP 2025-01 N022113-001 ADVIL ALLERGY AND CONGESTION RELIEF 4MG;200MG;10MG TABLET / ORAL RLD, RS 2011-12-21 03ed91905a0d…2025-01-19 17:59 UTC · 7 captures of this ZIP 2025-01 N022113-002 ADVIL MULTI-SYMPTOM COLD & FLU 4MG;200MG;10MG TABLET / ORAL RLD, RS 2017-04-28 03ed91905a0d…2024-12-13 21:23 UTC · 2 captures of this ZIP 2024-12 N022113-001 ADVIL ALLERGY AND CONGESTION RELIEF 4MG;200MG;10MG TABLET / ORAL RLD, RS 2011-12-21 2680178bc6a6…2024-12-13 21:23 UTC · 2 captures of this ZIP 2024-12 N022113-002 ADVIL MULTI-SYMPTOM COLD & FLU 4MG;200MG;10MG TABLET / ORAL RLD, RS 2017-04-28 2680178bc6a6…2024-09-14 05:58 UTC · 2 captures of this ZIP 2024-09 N022113-001 ADVIL ALLERGY AND CONGESTION RELIEF 4MG;200MG;10MG TABLET / ORAL RLD, RS 2011-12-21 5bbf6a4d5a75…2024-09-14 05:58 UTC · 2 captures of this ZIP 2024-09 N022113-002 ADVIL MULTI-SYMPTOM COLD & FLU 4MG;200MG;10MG TABLET / ORAL RLD, RS 2017-04-28 5bbf6a4d5a75…2024-11-08 22:44 UTC · 3 captures of this ZIP 2024-11 N022113-001 ADVIL ALLERGY AND CONGESTION RELIEF 4MG;200MG;10MG TABLET / ORAL RLD, RS 2011-12-21 d8e5a09893c0…2024-11-08 22:44 UTC · 3 captures of this ZIP 2024-11 N022113-002 ADVIL MULTI-SYMPTOM COLD & FLU 4MG;200MG;10MG TABLET / ORAL RLD, RS 2017-04-28 d8e5a09893c0…2024-10-29 15:01 UTC 2024-10 N022113-001 ADVIL ALLERGY AND CONGESTION RELIEF 4MG;200MG;10MG TABLET / ORAL RLD, RS 2011-12-21 d06236e962d9…2024-10-29 15:01 UTC 2024-10 N022113-002 ADVIL MULTI-SYMPTOM COLD & FLU 4MG;200MG;10MG TABLET / ORAL RLD, RS 2017-04-28 d06236e962d9…2024-08-13 05:28 UTC · 3 captures of this ZIP 2024-08 N022113-001 ADVIL ALLERGY AND CONGESTION RELIEF 4MG;200MG;10MG TABLET / ORAL RLD, RS 2011-12-21 79d66fd596c7…2024-08-13 05:28 UTC · 3 captures of this ZIP 2024-08 N022113-002 ADVIL MULTI-SYMPTOM COLD & FLU 4MG;200MG;10MG TABLET / ORAL RLD, RS 2017-04-28 79d66fd596c7…2024-07-13 05:37 UTC · 2 captures of this ZIP 2024-07 N022113-001 ADVIL ALLERGY AND CONGESTION RELIEF 4MG;200MG;10MG TABLET / ORAL RLD, RS 2011-12-21 301d65b070ca…2024-07-13 05:37 UTC · 2 captures of this ZIP 2024-07 N022113-002 ADVIL MULTI-SYMPTOM COLD & FLU 4MG;200MG;10MG TABLET / ORAL RLD, RS 2017-04-28 301d65b070ca…2024-06-18 03:08 UTC · 5 captures of this ZIP 2024-06 N022113-001 ADVIL ALLERGY AND CONGESTION RELIEF 4MG;200MG;10MG TABLET / ORAL RLD, RS 2011-12-21 1e350fbaab3a…2024-06-18 03:08 UTC · 5 captures of this ZIP 2024-06 N022113-002 ADVIL MULTI-SYMPTOM COLD & FLU 4MG;200MG;10MG TABLET / ORAL RLD, RS 2017-04-28 1e350fbaab3a…2024-05-31 18:47 UTC 2024-05 N022113-001 ADVIL ALLERGY AND CONGESTION RELIEF 4MG;200MG;10MG TABLET / ORAL RLD, RS 2011-12-21 8072bd15b7f6…2024-05-31 18:47 UTC 2024-05 N022113-002 ADVIL MULTI-SYMPTOM COLD & FLU 4MG;200MG;10MG TABLET / ORAL RLD, RS 2017-04-28 8072bd15b7f6…2022-06-29 02:47 UTC · 2 captures of this ZIP 2022-06 N022113-001 ADVIL ALLERGY AND CONGESTION RELIEF 4MG;200MG;10MG TABLET / ORAL RLD, RS 2011-12-21 5c6f7cd8ea54…2022-06-29 02:47 UTC · 2 captures of this ZIP 2022-06 N022113-002 ADVIL MULTI-SYMPTOM COLD & FLU 4MG;200MG;10MG TABLET / ORAL RLD, RS 2017-04-28 5c6f7cd8ea54…2022-04-08 23:34 UTC 2022-04 N022113-001 ADVIL ALLERGY AND CONGESTION RELIEF 4MG;200MG;10MG TABLET / ORAL RLD, RS 2011-12-21 5d02ea3f76ae…2022-04-08 23:34 UTC 2022-04 N022113-002 ADVIL MULTI-SYMPTOM COLD & FLU 4MG;200MG;10MG TABLET / ORAL RLD, RS 2017-04-28 5d02ea3f76ae…2022-04-04 05:41 UTC 2022-04 N022113-001 ADVIL ALLERGY AND CONGESTION RELIEF 4MG;200MG;10MG TABLET / ORAL RLD, RS 2011-12-21 4b0b4de00fa7…2022-04-04 05:41 UTC 2022-04 N022113-002 ADVIL MULTI-SYMPTOM COLD & FLU 4MG;200MG;10MG TABLET / ORAL RLD, RS 2017-04-28 4b0b4de00fa7…2019-12-13 00:20 UTC 2019-12 N022113-001 ADVIL ALLERGY AND CONGESTION RELIEF 4MG;200MG;10MG TABLET / ORAL RLD, RS 2011-12-21 74a2ff9319b5…2019-12-13 00:20 UTC 2019-12 N022113-002 ADVIL MULTI-SYMPTOM COLD & FLU 4MG;200MG;10MG TABLET / ORAL RLD, RS 2017-04-28 74a2ff9319b5…2022-03-09 01:35 UTC 2022-03 N022113-001 ADVIL ALLERGY AND CONGESTION RELIEF 4MG;200MG;10MG TABLET / ORAL RLD, RS 2011-12-21 bb7c543d1eb4…2022-03-09 01:35 UTC 2022-03 N022113-002 ADVIL MULTI-SYMPTOM COLD & FLU 4MG;200MG;10MG TABLET / ORAL RLD, RS 2017-04-28 bb7c543d1eb4…2021-12-28 21:50 UTC 2021-12 N022113-001 ADVIL ALLERGY AND CONGESTION RELIEF 4MG;200MG;10MG TABLET / ORAL RLD, RS 2011-12-21 782e0a99824c…2021-12-28 21:50 UTC 2021-12 N022113-002 ADVIL MULTI-SYMPTOM COLD & FLU 4MG;200MG;10MG TABLET / ORAL RLD, RS 2017-04-28 782e0a99824c…
Additional Listing Data#
Finished product Yes
Brand name base Advil Multi-Symptom Cold and Flu
Listing expiration 2026-12-31 Active Ingredients# Ingredient, Strength table Ingredient Strength CHLORPHENIRAMINE MALEATE 4 mg/1 IBUPROFEN 200 mg/1 PHENYLEPHRINE HYDROCHLORIDE 10 mg/1
Harmonized UNII identifiers# UNII identifiers page 1 of 1 · 3 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination V1Q0O9OJ9Z Internal UNII lookup WK2XYI10QM Internal UNII lookup 04JA59TNSJ Internal UNII lookup
Harmonized RxCUI identifiers# RxCUI identifiers page 1 of 1 · 1 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination 1310503 Internal RxNorm lookup
Harmonized SPL set identifiers# SPL set identifiers page 1 of 1 · 1 matching rows.
DailyMed Product Concepts# FDA-Initiated Inactive NDC Indexing# DailyMed Package Descriptions# Package NDC, Product, Description table Package NDC Product Description Form Quantity Strength SPL version 0573-0190-01 Advil Multi-Symptom Cold and Flu 1 in 1 POUCH TABLET, COATED 1 14 0573-0190-01 Advil Multi-Symptom Cold and Flu 50 in 1 TRAY TABLET, COATED 50 14 0573-0190-02 Advil Multi-Symptom Cold and Flu 2 in 1 CARTON TABLET, COATED 2 14 0573-0190-02 Advil Multi-Symptom Cold and Flu 1 in 1 POUCH TABLET, COATED 1 14 0573-0190-03 Advil Multi-Symptom Cold and Flu 1 in 1 POUCH TABLET, COATED 1 14 0573-0190-03 Advil Multi-Symptom Cold and Flu 3000 in 1 CASE TABLET, COATED 3000 14 0573-0190-10 Advil Multi-Symptom Cold and Flu 1 in 1 CARTON TABLET, COATED 1 14 0573-0190-10 Advil Multi-Symptom Cold and Flu 10 in 1 BLISTER PACK TABLET, COATED 10 14 0573-0190-20 Advil Multi-Symptom Cold and Flu 2 in 1 CARTON TABLET, COATED 2 14 0573-0190-20 Advil Multi-Symptom Cold and Flu 10 in 1 BLISTER PACK TABLET, COATED 10 14 0573-0190-30 Advil Multi-Symptom Cold and Flu 10 in 1 BLISTER PACK TABLET, COATED 10 14 0573-0190-30 Advil Multi-Symptom Cold and Flu 3 in 1 CARTON TABLET, COATED 3 14
DailyMed Dashboard NDC Coverage# NDC, Dashboard title, SPL version table NDC Dashboard title SPL version Validation Dashboard ZIP 0573-0190 ADVIL MULTI-SYMPTOM COLD AND FLU (CHLORPHENIRAMINE MALEATE, IBUPROFEN, PHENYLEPHRINE HCL) TABLET, COATED [HALEON US HOLDINGS LLC] 12 Current NDC, Legacy NDC, 12 package rows 20250410_7671d104-3c5c-4f63-b6b1-6c91c22592f8.zip
openFDA label cross-check# OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
Matched openFDA labels page 1 of 1 · 3 matching rows.
DailyMed RxNorm Mappings# Packages# Package NDC, 11-digit format, Description table Package NDC 11-digit format Description Units Marketing start Marketing end Sample Exclude flag Status 0573-0190-20 00573019020 2 BLISTER PACK in 1 CARTON (0573-0190-20) / 10 TABLET, COATED in 1 BLISTER PACK 2 blister pack 2018-06-25 0000-00-00 No No Current