Levothyroxine Sodium

Product NDC
24201-002
11-digit product format
242010002
Labeler code
24201
Product ID
24201-002_563fecaf-128d-4f6b-81c8-715b4d90a261
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
LEVOTHYROXINE SODIUM
Dosage form
INJECTION, SOLUTION
Route
INTRAVENOUS
Labeler
Hikma Pharmaceuticals USA Inc.
Application
NDA214253
Marketing category
NDA
Marketing start
2022-11-15
Substance
LEVOTHYROXINE SODIUM
Active strength
100 ug/mL
Pharmacologic classes
Thyroxine [CS], l-Thyroxine [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N214253-001LEVOTHYROXINE SODIUMLEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-17

Orange Book patents#

Current patent rows page 1 of 1 · 1 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N214253-001111544982036-07-20Drug product2021-10-27

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-17011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-1731067a03dcf5…
2025-08-23 18:47 UTC2025-08N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-176a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-17fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-17b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-1703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-172680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-175bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-17d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-17d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-1779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-17301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-171e350fbaab3a…
2024-05-31 18:47 UTC2024-05N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-178072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-175c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-175d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-174b0b4de00fa7…
2022-03-09 01:35 UTC2022-03N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-17bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-17782e0a99824c…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-176a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-171c564ffb4f44…
2023-12-20 04:57 UTC2023-12N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-17ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-17a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-179b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-17a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-173f0d92c62455…
2023-05-13 08:27 UTC2023-05N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-17053a50430f4f…
2023-01-26 05:58 UTC2023-01N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-173bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-173a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-17f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-17e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-17cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N214253-001LEVOTHYROXINE SODIUM100MCG/MLSOLUTION / INTRAVENOUSRLD, RS2021-05-17a50c72e98297…

Observed Orange Book patent history#

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N214253-001111544982036-07-20Drug product2021-10-27011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214253-001111544982036-07-20Drug product2021-10-2731067a03dcf5…
2025-08-23 18:47 UTC2025-08N214253-001111544982036-07-20Drug product2021-10-276a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N214253-001111544982036-07-20Drug product2021-10-27fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N214253-001111544982036-07-20Drug product2021-10-27b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N214253-001111544982036-07-20Drug product2021-10-2703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N214253-001111544982036-07-20Drug product2021-10-272680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N214253-001111544982036-07-20Drug product2021-10-275bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N214253-001111544982036-07-20Drug product2021-10-27d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N214253-001111544982036-07-20Drug product2021-10-27d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N214253-001111544982036-07-20Drug product2021-10-2779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N214253-001111544982036-07-20Drug product2021-10-27301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N214253-001111544982036-07-20Drug product2021-10-271e350fbaab3a…
2024-05-31 18:47 UTC2024-05N214253-001111544982036-07-20Drug product2021-10-278072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N214253-001111544982036-07-20Drug product2021-10-275c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N214253-001111544982036-07-20Drug product2021-10-275d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N214253-001111544982036-07-20Drug product2021-10-274b0b4de00fa7…
2022-03-09 01:35 UTC2022-03N214253-001111544982036-07-20Drug product2021-10-27bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N214253-001111544982036-07-20Drug product2021-10-27782e0a99824c…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N214253-001111544982036-07-20Drug product2021-10-276a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N214253-001111544982036-07-20Drug product2021-10-271c564ffb4f44…
2023-12-20 04:57 UTC2023-12N214253-001111544982036-07-20Drug product2021-10-27ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N214253-001111544982036-07-20Drug product2021-10-27a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N214253-001111544982036-07-20Drug product2021-10-279b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N214253-001111544982036-07-20Drug product2021-10-27a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N214253-001111544982036-07-20Drug product2021-10-273f0d92c62455…
2023-05-13 08:27 UTC2023-05N214253-001111544982036-07-20Drug product2021-10-27053a50430f4f…
2023-01-26 05:58 UTC2023-01N214253-001111544982036-07-20Drug product2021-10-273bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N214253-001111544982036-07-20Drug product2021-10-273a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N214253-001111544982036-07-20Drug product2021-10-27f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N214253-001111544982036-07-20Drug product2021-10-27e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N214253-001111544982036-07-20Drug product2021-10-27cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N214253-001111544982036-07-20Drug product2021-10-27a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Levothyroxine Sodium
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
LEVOTHYROXINE SODIUM100 ug/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
9J765S329GInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2621123Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
6279390b-ee61-4ef9-ac15-25537ca783c1Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
97c252d3-9bb8-4530-bb44-9824dc7cf556Product name620250729
6c43b71c-35e6-4db3-ba24-c6ef42ff7003Product name320240207
890fd4bf-1a80-42b7-be1b-2d0259d5f0c8Product name520240207
c8ad26bf-af73-460b-b74e-1eff16cc4f9fProduct name520240207
01383843-4069-43cf-aa76-dc17a6f9f8c4Product name220230123
978cca7d-a938-4791-8322-da48d90a63efProduct name120230113
65f86ba3-8816-4e12-899b-18290c8de551Product name220210614
f16ab90f-08c2-40be-a543-66d9827cd1f3Product name120210601
6a33ec05-2ae2-45e5-ab82-2d94b3303923Product name120190709
93355a10-1c44-4c92-a11d-7d995e0200d9Product name120190219
0ca1d589-929b-4b33-bc5b-1d84abdafa6aProduct name120150324
fc363c46-397b-4476-ac0f-70e43e8e4592Product name120150324
1681bc73-b05f-12c3-1075-382ae39f449cProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
24201-002-01Levothyroxine Sodium2 mL in 1 VIAL, SINGLE-DOSEINJECTION, SOLUTION24
24201-002-01Levothyroxine Sodium1 in 1 CARTONINJECTION, SOLUTION14

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
24201-002-01ML - Milliliter24201-00211f84a8c-efa5-4afd-a047-2537adfa446e12022-12-07

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
24201-002LEVOTHYROXINE SODIUM INJECTION, SOLUTION [HIKMA PHARMACEUTICALS USA INC.]4Current NDC, Legacy NDC, 2 package rows20250522_6279390b-ee61-4ef9-ac15-25537ca783c1.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Levothyroxine SodiumLEVOTHYROXINE SODIUMHikma Pharmaceuticals USA Inc.6279390b-ee61-4ef9-ac15-25537ca783c12024-07-10Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 214253
application number: NDA214253
ndc (product): 24201-002

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
2621123levothyroxine sodium 100 MCG in 1 ML InjectionPSN6279390b-ee61-4ef9-ac15-25537ca783c14
26211231 ML levothyroxine sodium 0.1 MG/ML InjectionSCD6279390b-ee61-4ef9-ac15-25537ca783c14
2621123levothyroxine sodium 100 MCG per 1 ML InjectionSY6279390b-ee61-4ef9-ac15-25537ca783c14

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
24201-002-01242010002011 VIAL, SINGLE-DOSE in 1 CARTON (24201-002-01) / 2 mL in 1 VIAL, SINGLE-DOSE2022-11-150000-00-00NoNoCurrent