VITRASE

Product NDC: 24208-002
11-digit product format: 242080002
Labeler code: 24208
Product ID: 24208-002_22bb835d-0433-4e75-bada-5cb60113d298
Type: HUMAN PRESCRIPTION DRUG
Nonproprietary name: hyaluronidase, ovine
Dosage form: INJECTION, SOLUTION
Route: SUBCUTANEOUS
Labeler: Bausch & Lomb Incorporated
Application: BLA021640
Marketing category: BLA
Marketing start: 2005-02-01
Marketing end: 0000-00-00
Substance: HYALURONIDASE, OVINE
Active strength: 200 [USP'U]/mL
Pharmacologic classes: Endoglycosidase [EPC],Glycoside Hydrolases [CS]
NDC exclude flag: No
Listing certified through: 2021-12-31
Current FDA listing: Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 4 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Source date
excluded product	product	24208-002		D	Discontinued by firm	2026-10-05
excluded product	product	24208-002		D	Discontinued by firm	2026-10-05
excluded package	package	24208-002	24208-002-02	D	Discontinued by firm	2026-10-05
excluded package	package	24208-002	24208-002-01	D	Discontinued by firm	2026-10-05

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 36 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Package NDC	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	excluded product	product		`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	24208-002-02	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	24208-002-01	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded product	product		`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	24208-002-02	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	24208-002-01	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded product	product		`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	24208-002-02	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	24208-002-01	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded product	product		`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	24208-002-02	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	24208-002-01	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded product	product		`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	24208-002-02	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	24208-002-01	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded product	product		`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	24208-002-02	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	24208-002-01	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded product	product		`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	24208-002-02	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	24208-002-01	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded product	product		`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	24208-002-02	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	24208-002-01	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded product	product		`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	24208-002-02	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	24208-002-01	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded product	product		`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	24208-002-02	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	24208-002-01	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded product	product		`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	24208-002-02	`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	24208-002-01	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded product	product		`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	24208-002-02	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	24208-002-01	`557ba5c1ecfa…`	`9c80585c8c6e…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
24208-002-01	ML - Milliliter	24208-002	4d7349a6-456c-4aab-b64b-19105ba337df	1	2013-05-02
24208-002-02	ML - Milliliter	24208-002	4a0a1077-df82-4cf0-9ec4-1e403d720525	1	2015-10-02

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
HYALURONIDASE, OVINE	ACTIVE INGREDIENT	64R4OHP8T0	VITRASE (HYALURONIDASE, OVINE) INJECTION, SOLUTION [BAUSCH & LOMB INCORPORATED]	1
HYALURONIDASE, OVINE	ACTIVE MOIETY	64R4OHP8T0	VITRASE (HYALURONIDASE, OVINE) INJECTION, SOLUTION [BAUSCH & LOMB INCORPORATED]	1
LACTOSE	INACTIVE INGREDIENT	J2B2A4N98G	VITRASE (HYALURONIDASE, OVINE) INJECTION, SOLUTION [BAUSCH & LOMB INCORPORATED]	1
POTASSIUM PHOSPHATE, DIBASIC	INACTIVE INGREDIENT	CI71S98N1Z	VITRASE (HYALURONIDASE, OVINE) INJECTION, SOLUTION [BAUSCH & LOMB INCORPORATED]	1
POTASSIUM PHOSPHATE, MONOBASIC	INACTIVE INGREDIENT	4J9FJ0HL51	VITRASE (HYALURONIDASE, OVINE) INJECTION, SOLUTION [BAUSCH & LOMB INCORPORATED]	1
SODIUM CHLORIDE	INACTIVE INGREDIENT	451W47IQ8X	VITRASE (HYALURONIDASE, OVINE) INJECTION, SOLUTION [BAUSCH & LOMB INCORPORATED]	1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
24208-002	VITRASE (HYALURONIDASE, OVINE) INJECTION, SOLUTION [BAUSCH & LOMB INCORPORATED]	8	Legacy NDC	20240530_21fbd12e-4a12-4ad1-ad01-964cd5ec9996.zip

Purple Book Biologic Products#

BLA, Proprietary name, Proper name table
BLA	Proprietary name	Proper name	License type	Status	Latest source
021640	Vitrase	hyaluronidase	351(a)	Disc	2026-09-01

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
64R4OHP8T0	HYALURONIDASE, OVINE	488712-31-8	HYALURONIDASE, OVINE

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Marketing start	Marketing end	Sample	Exclude flag	Status
24208-002-02	24208000202	2 VIAL, SINGLE-USE in 1 CARTON (24208-002-02) > 1.2 mL in 1 VIAL, SINGLE-USE	2005-02-01	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
VITRASE	Bausch & Lomb Incorporated \| Alliance Medical Products, Inc. (dba Siegfried Irvine)	2024-05-31	HUMAN PRESCRIPTION DRUG LABEL	8