BRIMONIDINE

Product NDC
45802-078
Requested package NDC
45802-078-30
11-digit product format
458020078
Labeler code
45802
Product ID
45802-078_6d6fa6f0-e1c6-4ea1-a4fb-8ad511a95d75
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
brimonidine
Dosage form
GEL
Route
TOPICAL
Labeler
Padagis Israel Pharmaceuticals Ltd
Application
ANDA209158
Marketing category
ANDA
Marketing start
2023-01-01
Substance
BRIMONIDINE TARTRATE
Active strength
5 mg/g
Pharmacologic classes
Adrenergic alpha-Agonists [MoA], alpha-Adrenergic Agonist [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A209158-001BRIMONIDINE TARTRATEBRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-23

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A209158-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-23011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-2331067a03dcf5…
2025-08-23 18:47 UTC2025-08A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-236a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-23fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-23b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-2303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-232680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-235bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-23d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-23d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-2379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-23301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-231e350fbaab3a…
2024-05-31 18:47 UTC2024-05A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-238072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICAL2021-09-235c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-235d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-234b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-23bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-23782e0a99824c…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-236a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-231c564ffb4f44…
2023-12-20 04:57 UTC2023-12A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-23ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-23a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-239b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-23a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-233f0d92c62455…
2023-05-13 08:27 UTC2023-05A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-23053a50430f4f…
2023-01-26 05:58 UTC2023-01A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-233bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICAL2021-09-233a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICAL2021-09-23f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICAL2021-09-23e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICAL2021-09-23cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A209158-001BRIMONIDINE TARTRATEEQ 0.33% BASEGEL / TOPICALAB2021-09-23a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A209158-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A209158-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A209158-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A209158-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A209158-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A209158-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A209158-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A209158-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A209158-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A209158-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A209158-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A209158-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A209158-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A209158-001AB18072bd15b7f6…
2022-04-08 23:34 UTC2022-04A209158-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A209158-001AB14b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A209158-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A209158-001AB1782e0a99824c…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A209158-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A209158-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A209158-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A209158-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A209158-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A209158-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A209158-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05A209158-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01A209158-001AB13bdfa0b2c4d7…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A209158-001AB1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
BRIMONIDINE
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
BRIMONIDINE TARTRATE5 mg/g

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
4S9CL2DY2HInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1437707Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
c899b329-cc5e-4443-8e94-451314de47c9Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
c6c0c444-a6ba-2fb5-a7bc-7f0443fa5791Product name420251208
8ec6541e-9842-115f-62bf-f7c9ab3aeddbProduct name320250805
39b7fcf4-8865-6d40-d24d-9b8c28bd6345Product name520250123
c93ffd9a-5bad-44d8-b5e5-16ef4d2fee72Product name120220316

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
45802-078-30BRIMONIDINE1 in 1 CARTONGEL14
45802-078-30BRIMONIDINE30 g in 1 BOTTLE, PUMPGEL304

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
45802-078-30GM - Gram45802-0780a10231e-5d96-4357-9009-6f650951aa7c12023-01-09

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
45802-078BRIMONIDINE GEL [PADAGIS ISRAEL PHARMACEUTICALS LTD]3Current NDC, Legacy NDC, 2 package rows20230101_c899b329-cc5e-4443-8e94-451314de47c9.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
BRIMONIDINEBRIMONIDINEPadagis Israel Pharmaceuticals Ltdc899b329-cc5e-4443-8e94-451314de47c92024-07-31Warnings, Adverse reactionsExact identifier
application applno (ANDA): 209158
application number: ANDA209158
ndc (package): 45802-078-30
ndc (product): 45802-078
ndc11 (package): 45802007830
BRIMONIDINEBRIMONIDINEBryant Ranch Prepack9f17bf0c-d880-4328-bf92-00ac81d02fd12023-02-03Warnings, Adverse reactionsExact identifier
application applno (ANDA): 209158
application number: ANDA209158

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1437707brimonidine 0.33 % Topical GelPSN9f17bf0c-d880-4328-bf92-00ac81d02fd1100
1437707brimonidine 0.0033 MG/MG Topical GelSCD9f17bf0c-d880-4328-bf92-00ac81d02fd1100
1437707brimonidine 0.33 % (as brimonidine tartrate) Topical GelSY9f17bf0c-d880-4328-bf92-00ac81d02fd1100
1437707brimonidine 0.33 % Topical GelPSNc899b329-cc5e-4443-8e94-451314de47c94
1437707brimonidine 0.0033 MG/MG Topical GelSCDc899b329-cc5e-4443-8e94-451314de47c94
1437707brimonidine 0.33 % (as brimonidine tartrate) Topical GelSYc899b329-cc5e-4443-8e94-451314de47c94

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
45802-078-30458020078301 BOTTLE, PUMP in 1 CARTON (45802-078-30) / 30 g in 1 BOTTLE, PUMP2023-01-010000-00-00NoNoCurrent