ERIVEDGE

Product NDC
50242-140
11-digit product format
502420140
Labeler code
50242
Product ID
50242-140_d8b343ee-5767-4934-ad68-5164d4de5228
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
vismodegib
Dosage form
CAPSULE
Route
ORAL
Labeler
Genentech, Inc.
Application
NDA203388
Marketing category
NDA
Marketing start
2012-01-30
Substance
VISMODEGIB
Active strength
150 mg/1
Pharmacologic classes
Hedgehog Pathway Inhibitor [EPC], Smoothened Receptor Antagonists [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N203388-001ERIVEDGEVISMODEGIB150MGCAPSULE / ORALRLD, RS2012-01-30

Orange Book patents#

Current patent rows page 1 of 1 · 2 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N203388-00178883642028-11-11Drug substance, Drug product2012-02-27
N203388-00192789612028-12-15U-18252016-03-25

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-30011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-3031067a03dcf5…
2025-08-23 18:47 UTC2025-08N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-306a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-30fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-30b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-3003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-302680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-305bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-30d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-30d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-3079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-30301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-301e350fbaab3a…
2024-05-31 18:47 UTC2024-05N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-308072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-305c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-305d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-304b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-3074a2ff9319b5…
2022-03-09 01:35 UTC2022-03N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-30bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-30782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-3087673890dc5c…
2021-03-12 10:30 UTC2021-03N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-305aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-308869cabd3fbd…
2020-11-12 02:37 UTC2020-11N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-30c0c555d07b60…
2019-12-14 00:12 UTC2019-12N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-303f01610625f2…
2019-09-15 20:21 UTC2019-09N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-30b00525d2431f…
2019-07-19 19:46 UTC2019-07N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-30ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-306a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-301c564ffb4f44…
2023-12-20 04:57 UTC2023-12N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-30ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-30a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-309b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-30a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-303f0d92c62455…
2023-05-13 08:27 UTC2023-05N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-30053a50430f4f…
2023-01-26 05:58 UTC2023-01N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-303bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-303a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-30f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-30e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N203388-001ERIVEDGE150MGCAPSULE / ORALRLD, RS2012-01-30cb3db0bc1861…

Observed Orange Book patent history#

Patent history page 1 of 3 · 113 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N203388-00178883642028-11-11Drug substance, Drug product2012-02-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02N203388-00192789612028-12-15U-18252016-03-25011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203388-00197901832025-09-02U-31092021-05-1931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203388-00178883642028-11-11Drug substance, Drug product2012-02-2731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N203388-00192789612028-12-15U-18252016-03-2531067a03dcf5…
2025-08-23 18:47 UTC2025-08N203388-00197901832025-09-02U-31092021-05-196a471c1ec25d…
2025-08-23 18:47 UTC2025-08N203388-00178883642028-11-11Drug substance, Drug product2012-02-276a471c1ec25d…
2025-08-23 18:47 UTC2025-08N203388-00192789612028-12-15U-18252016-03-256a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N203388-00197901832025-09-02U-31092021-05-19fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N203388-00178883642028-11-11Drug substance, Drug product2012-02-27fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N203388-00192789612028-12-15U-18252016-03-25fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N203388-00197901832025-09-02U-31092021-05-19b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N203388-00178883642028-11-11Drug substance, Drug product2012-02-27b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N203388-00192789612028-12-15U-18252016-03-25b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N203388-00197901832025-09-02U-31092021-05-1903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N203388-00178883642028-11-11Drug substance, Drug product2012-02-2703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N203388-00192789612028-12-15U-18252016-03-2503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N203388-00197901832025-09-02U-31092021-05-192680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N203388-00178883642028-11-11Drug substance, Drug product2012-02-272680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N203388-00192789612028-12-15U-18252016-03-252680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N203388-00197901832025-09-02U-31092021-05-195bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N203388-00178883642028-11-11Drug substance, Drug product2012-02-275bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N203388-00192789612028-12-15U-18252016-03-255bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N203388-00197901832025-09-02U-31092021-05-19d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N203388-00178883642028-11-11Drug substance, Drug product2012-02-27d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N203388-00192789612028-12-15U-18252016-03-25d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N203388-00197901832025-09-02U-31092021-05-19d06236e962d9…
2024-10-29 15:01 UTC2024-10N203388-00178883642028-11-11Drug substance, Drug product2012-02-27d06236e962d9…
2024-10-29 15:01 UTC2024-10N203388-00192789612028-12-15U-18252016-03-25d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N203388-00197901832025-09-02U-31092021-05-1979d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N203388-00178883642028-11-11Drug substance, Drug product2012-02-2779d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N203388-00192789612028-12-15U-18252016-03-2579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N203388-00197901832025-09-02U-31092021-05-19301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N203388-00178883642028-11-11Drug substance, Drug product2012-02-27301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N203388-00192789612028-12-15U-18252016-03-25301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N203388-00197901832025-09-02U-31092021-05-191e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N203388-00178883642028-11-11Drug substance, Drug product2012-02-271e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N203388-00192789612028-12-15U-18252016-03-251e350fbaab3a…
2024-05-31 18:47 UTC2024-05N203388-00197901832025-09-02U-31092021-05-198072bd15b7f6…
2024-05-31 18:47 UTC2024-05N203388-00178883642028-11-11Drug substance, Drug product2012-02-278072bd15b7f6…

Additional Listing Data#

Finished product
Yes
Brand name base
ERIVEDGE
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
VISMODEGIB150 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
25X868M3DSInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1242992Internal RxNorm lookup
1242998Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
eb368bb6-80e3-4df9-8a85-91df0a2ada6aAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
6541d7ca-5b8e-1c7e-93ec-dceb0fa5e3b8Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
50242-140-01ERIVEDGE28 in 1 BOTTLE, PLASTICCAPSULE2815
50242-140-01ERIVEDGE1 in 1 CARTONCAPSULE115
50242-140-86ERIVEDGE1 in 1 CARTONCAPSULE115
50242-140-86ERIVEDGE28 in 1 BOTTLE, PLASTICCAPSULE2815

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
50242-140-01EA - Each50242-1403b0b9f59-1d9b-459b-96d8-af824e61fcad12012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
vismodegibACTIVE INGREDIENT25X868M3DSERIVEDGE (VISMODEGIB) CAPSULE [GENENTECH, INC.]4
vismodegibACTIVE MOIETY25X868M3DSERIVEDGE (VISMODEGIB) CAPSULE [GENENTECH, INC.]4
cellulose, microcrystallineINACTIVE INGREDIENTOP1R32D61UERIVEDGE (VISMODEGIB) CAPSULE [GENENTECH, INC.]4
ferric oxide redINACTIVE INGREDIENT1K09F3G675ERIVEDGE (VISMODEGIB) CAPSULE [GENENTECH, INC.]4
ferrosoferric oxideINACTIVE INGREDIENTXM0M87F357ERIVEDGE (VISMODEGIB) CAPSULE [GENENTECH, INC.]4
gelatinINACTIVE INGREDIENT2G86QN327LERIVEDGE (VISMODEGIB) CAPSULE [GENENTECH, INC.]4
lactose monohydrateINACTIVE INGREDIENTEWQ57Q8I5XERIVEDGE (VISMODEGIB) CAPSULE [GENENTECH, INC.]4
magnesium stearateINACTIVE INGREDIENT70097M6I30ERIVEDGE (VISMODEGIB) CAPSULE [GENENTECH, INC.]4
povidone K29/32INACTIVE INGREDIENT390RMW2PEQERIVEDGE (VISMODEGIB) CAPSULE [GENENTECH, INC.]4
sodium lauryl sulfateINACTIVE INGREDIENT368GB5141JERIVEDGE (VISMODEGIB) CAPSULE [GENENTECH, INC.]4
sodium starch glycolate type a potatoINACTIVE INGREDIENT5856J3G2A2ERIVEDGE (VISMODEGIB) CAPSULE [GENENTECH, INC.]4
talcINACTIVE INGREDIENT7SEV7J4R1UERIVEDGE (VISMODEGIB) CAPSULE [GENENTECH, INC.]4
titanium dioxideINACTIVE INGREDIENT15FIX9V2JPERIVEDGE (VISMODEGIB) CAPSULE [GENENTECH, INC.]4

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
50242-140ERIVEDGE (VISMODEGIB) CAPSULE [GENENTECH, INC.]15Current NDC, Legacy NDC, 4 package rows20241210_eb368bb6-80e3-4df9-8a85-91df0a2ada6a.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
ERIVEDGEVISMODEGIBGenentech, Inc.eb368bb6-80e3-4df9-8a85-91df0a2ada6a2024-12-02Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 203388
application number: NDA203388
ndc (product): 50242-140

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1242998Erivedge 150 MG Oral CapsulePSNeb368bb6-80e3-4df9-8a85-91df0a2ada6a15
1242992vismodegib 150 MG Oral CapsulePSNeb368bb6-80e3-4df9-8a85-91df0a2ada6a15
1242998vismodegib 150 MG Oral Capsule [Erivedge]SBDeb368bb6-80e3-4df9-8a85-91df0a2ada6a15
1242992vismodegib 150 MG Oral CapsuleSCDeb368bb6-80e3-4df9-8a85-91df0a2ada6a15
1242998Erivedge 150 MG Oral CapsuleSYeb368bb6-80e3-4df9-8a85-91df0a2ada6a15

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
50242-140-01502420140011 BOTTLE, PLASTIC in 1 CARTON (50242-140-01) / 28 CAPSULE in 1 BOTTLE, PLASTIC2012-01-300000-00-00NoNoCurrent
50242-140-86502420140861 BOTTLE, PLASTIC in 1 CARTON (50242-140-86) / 28 CAPSULE in 1 BOTTLE, PLASTIC2013-04-090000-00-00YesNoCurrent