Sudafed Sinus 12 Hour Pressure plus Pain

Product NDC
50580-434
Requested package NDC
50580-434-01
11-digit product format
505800434
Labeler code
50580
Product ID
50580-434_21abbf03-2010-4650-e063-6294a90a6edb
Type
HUMAN OTC DRUG
Nonproprietary name
Naproxen sodium and Pseudoephedrine Hydrochloride
Dosage form
TABLET, MULTILAYER, EXTENDED RELEASE
Route
ORAL
Labeler
Kenvue Brands LLC
Application
ANDA076518
Marketing category
ANDA
Marketing start
2019-06-17
Substance
NAPROXEN SODIUM; PSEUDOEPHEDRINE HYDROCHLORIDE
Active strength
220; 120 mg/1; mg/1
Pharmacologic classes
Adrenergic alpha-Agonists [MoA], Anti-Inflammatory Agents, Non-Steroidal [CS], Cyclooxygenase Inhibitors [MoA], Nonsteroidal Anti-inflammatory Drug [EPC], alpha-Adrenergic Agonist [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDENAPROXEN SODIUM; PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-17

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-17011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-1731067a03dcf5…
2025-08-23 18:47 UTC2025-08A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-176a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-17fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-17b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-1703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-172680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-175bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-17d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-17d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-1779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-17301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-171e350fbaab3a…
2024-05-31 18:47 UTC2024-05A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-178072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-175c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-175d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-174b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORAL2004-03-1774a2ff9319b5…
2022-03-09 01:35 UTC2022-03A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-17bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORAL2004-03-17782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORAL2004-03-1787673890dc5c…
2021-03-12 10:30 UTC2021-03A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORAL2004-03-175aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORAL2004-03-178869cabd3fbd…
2020-11-12 02:37 UTC2020-11A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORAL2004-03-17c0c555d07b60…
2019-12-14 00:12 UTC2019-12A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORAL2004-03-173f01610625f2…
2019-09-15 20:21 UTC2019-09A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDEEQ 200MG BASE;120MGTABLET, EXTENDED RELEASE / ORAL2004-03-17b00525d2431f…
2019-07-19 19:46 UTC2019-07A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDEEQ 200MG BASE;120MGTABLET, EXTENDED RELEASE / ORAL2004-03-17ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-176a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-171c564ffb4f44…
2023-12-20 04:57 UTC2023-12A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-17ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-17a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-179b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-17a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-173f0d92c62455…
2023-05-13 08:27 UTC2023-05A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-17053a50430f4f…
2023-01-26 05:58 UTC2023-01A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-173bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-173a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-17f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-17e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A076518-001NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE220MG;120MGTABLET, EXTENDED RELEASE / ORALRS2004-03-17cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
Sudafed Sinus 12 Hour Pressure plus Pain
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
NAPROXEN SODIUM220 mg/1
PSEUDOEPHEDRINE HYDROCHLORIDE120 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
9TN87S3A3CInternal UNII lookup
6V9V2RYJ8NInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1367426Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
305adca3-cdae-41e5-a10a-99d9dd0fe390Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
fef6ad89-235f-4274-ba49-a8e53642473eProduct name220250225
87fed3e6-8fba-48ef-96b0-3a7fb54b96ffProduct name320230306
ba088a92-ab5e-b2d4-e908-f5ea691b7587Product name720210201
b5fdaaec-7251-4da6-9cb2-4e9e76939ec8Product name120200623
e76dbbc1-775d-722c-08ff-ed45e8a80defProduct name320181002
0fdb98e2-b951-a1ce-5715-2b187ba500efProduct name420170718
e974e22d-8688-7d92-1e87-40c1079e170cProduct name320151125
e8718272-64cb-4436-969b-176c3067c8f4Product name120150609
30c51294-7ae9-8007-7de6-58222684a0beProduct name120140508
4f26f669-fc6c-40ef-9e26-1c7b2390ee66Product name120140508
6f4f4521-fd56-1ae6-888b-3b021bd75c7cProduct name120140508
70a83adc-6047-bbea-5a08-dfd304aa47d2Product name120140508
858ce051-9941-aafc-8c7c-44a8e0227463Product name120140508
b893258d-0942-3d8a-3411-056ea0788ff5Product name120140508
ce67e27d-1d21-5465-4409-b0662dd99d4dProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
50580-434-01Sudafed Sinus 12 Hour Pressure plus Pain2 in 1 CARTONTABLET, MULTILAYER, EXTENDED REL26
50580-434-01Sudafed Sinus 12 Hour Pressure plus Pain8 in 1 BLISTER PACKTABLET, MULTILAYER, EXTENDED REL86

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
50580-434-01EA - Each50580-4347839afcc-6d88-4b2d-9c2e-32ffe602531c12019-12-10

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
50580-434SUDAFED SINUS 12 HOUR PRESSURE PLUS PAIN (NAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDE) TABLET, MULTILAYER, EXTENDED RELEASE [KENVUE BRANDS LLC]6Current NDC, Legacy NDC, 2 package rows20241109_305adca3-cdae-41e5-a10a-99d9dd0fe390.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 9 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Mucinex DS 12HR COLD, FEVER and SINUSNAPROXEN SODIUM, PSEUDOEPHEDRINE HYDROCHLORIDEReckitt Benckiser LLC4e7e6674-c1ce-ea61-e063-6294a90afe042026-05-12WarningsExact identifier
application applno (ANDA): 076518
application number: ANDA076518
Aleve-D Sinus and HeadacheNAPROXEN SODIUM, PSEUDOEPHEDRINE HYDROCHLORIDEBayer HealthCare LLC.5ab980c0-c48a-233b-e053-2991aa0a4fd12025-12-04WarningsExact identifier
application applno (ANDA): 076518
application number: ANDA076518
Aleve-D Sinus and ColdNAPROXEN SODIUM, PSEUDEOEPHEDRINE HYDROCHLORIDEBayer HealthCare LLC.599ea6c8-03ad-536e-e053-2991aa0a83a32025-12-04WarningsExact identifier
application applno (ANDA): 076518
application number: ANDA076518
Leader All Day Sinus and Cold DNAPROXEN SODIUM, PSEUDOEPHEDRINE HCLCardinal Health 110, LLC. dba Leader83f7cfbb-ab84-4594-ae7a-4a657385c8a72025-04-25WarningsExact identifier
application applno (ANDA): 076518
application number: ANDA076518
All Day Sinus and Cold DNAPROXEN SODIUM, PSEUDOEPHEDRINE HCLWalgreen Companyb0417ce5-3a5e-42cb-8672-9f2b133c91ca2025-04-25WarningsExact identifier
application applno (ANDA): 076518
application number: ANDA076518
Sinus and Cold DNAPROXEN SODIUM, PSEUDOEPHEDRINE HCLMeijer Distribution Inccb78330b-d8a3-4c16-bbb0-d31368a542e62025-04-18WarningsExact identifier
application applno (ANDA): 076518
application number: ANDA076518
Topcare Sinus and Cold DNAPROXEN SODIUM, PSEUDOEPHEDRINE HCLTopco Associates LLC55c177ce-1729-4a9b-a5ae-2b6c96fbc27a2025-04-17WarningsExact identifier
application applno (ANDA): 076518
application number: ANDA076518
Sudafed Sinus 12 Hour Pressure plus PainNAPROXEN SODIUM AND PSEUDOEPHEDRINE HYDROCHLORIDEKenvue Brands LLC305adca3-cdae-41e5-a10a-99d9dd0fe3902024-11-08WarningsExact identifier
application applno (ANDA): 076518
application number: ANDA076518
ndc (package): 50580-434-01
ndc (product): 50580-434
ndc11 (package): 50580043401
Sinus and Cold DNAPROXEN SODIUM, PSEUDOEPHEDRINE HYDROCHLORIDECVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED9e142ac7-c8b1-449b-a224-c7db0fc0e4cf2024-07-10WarningsExact identifier
application applno (ANDA): 076518
application number: ANDA076518

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1367426naproxen sodium 220 MG / pseudoephedrine HCl 120 MG 12HR Extended Release Oral TabletPSN305adca3-cdae-41e5-a10a-99d9dd0fe3906
136742612 HR naproxen sodium 220 MG / pseudoephedrine hydrochloride 120 MG Extended Release Oral TabletSCD305adca3-cdae-41e5-a10a-99d9dd0fe3906
1367426naproxen sodium 220 MG / pseudoephedrine hydrochloride 120 MG 12 HR Extended Release Oral TabletSY305adca3-cdae-41e5-a10a-99d9dd0fe3906

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
50580-434-01505800434012 BLISTER PACK in 1 CARTON (50580-434-01) / 8 TABLET, MULTILAYER, EXTENDED RELEASE in 1 BLISTER PACK2 blister pack2019-06-170000-00-00NoNoCurrent