CLONIDINE HCI

Product NDC
51662-1346
11-digit product format
516621346
Labeler code
51662
Product ID
51662-1346_ef6d3bae-5393-440c-e053-2995a90a3a9f
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
CLONIDINE HCI
Dosage form
INJECTION, SOLUTION
Route
INTRAVENOUS
Labeler
HF Acquisition Co LLC, DBA HealthFirst
Application
ANDA200300
Marketing category
ANDA
Marketing start
2018-12-23
Substance
CLONIDINE HYDROCHLORIDE
Active strength
100 ug/mL
Pharmacologic classes
Adrenergic alpha2-Agonists [MoA], Central alpha-2 Adrenergic Agonist [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A200300-001CLONIDINE HYDROCHLORIDECLONIDINE HYDROCHLORIDE1MG/10ML (0.1MG/ML)INJECTABLE / INJECTIONAP2011-01-26
A200300-002CLONIDINE HYDROCHLORIDECLONIDINE HYDROCHLORIDE5MG/10ML (0.5MG/ML)INJECTABLE / INJECTIONAPRS2011-01-26

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A200300-001AP
A200300-002AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A200300-001CLONIDINE HYDROCHLORIDE1MG/10ML (0.1MG/ML)INJECTABLE / INJECTIONAP2011-01-26011fe1cb6892…
2026-02-19 14:30 UTC2026-02A200300-002CLONIDINE HYDROCHLORIDE5MG/10ML (0.5MG/ML)INJECTABLE / INJECTIONAPRS2011-01-26011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A200300-001CLONIDINE HYDROCHLORIDE1MG/10ML (0.1MG/ML)INJECTABLE / INJECTIONAP2011-01-2631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A200300-002CLONIDINE HYDROCHLORIDE5MG/10ML (0.5MG/ML)INJECTABLE / INJECTIONAPRS2011-01-2631067a03dcf5…
2025-08-23 18:47 UTC2025-08A200300-001CLONIDINE HYDROCHLORIDE1MG/10ML (0.1MG/ML)INJECTABLE / INJECTIONAP2011-01-266a471c1ec25d…
2025-08-23 18:47 UTC2025-08A200300-002CLONIDINE HYDROCHLORIDE5MG/10ML (0.5MG/ML)INJECTABLE / INJECTIONAPRS2011-01-266a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A200300-001CLONIDINE HYDROCHLORIDE1MG/10ML (0.1MG/ML)INJECTABLE / INJECTIONAP2011-01-26fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A200300-002CLONIDINE HYDROCHLORIDE5MG/10ML (0.5MG/ML)INJECTABLE / INJECTIONAPRS2011-01-26fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A200300-001CLONIDINE HYDROCHLORIDE1MG/10ML (0.1MG/ML)INJECTABLE / INJECTIONAP2011-01-26b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A200300-002CLONIDINE HYDROCHLORIDE5MG/10ML (0.5MG/ML)INJECTABLE / INJECTIONAPRS2011-01-26b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A200300-001CLONIDINE HYDROCHLORIDE1MG/10ML (0.1MG/ML)INJECTABLE / INJECTIONAP2011-01-2603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A200300-002CLONIDINE HYDROCHLORIDE5MG/10ML (0.5MG/ML)INJECTABLE / INJECTIONAPRS2011-01-2603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A200300-001CLONIDINE HYDROCHLORIDE1MG/10ML (0.1MG/ML)INJECTABLE / INJECTIONAP2011-01-262680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A200300-002CLONIDINE HYDROCHLORIDE5MG/10ML (0.5MG/ML)INJECTABLE / INJECTIONAPRS2011-01-262680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A200300-001CLONIDINE HYDROCHLORIDE1MG/10ML (0.1MG/ML)INJECTABLE / INJECTIONAP2011-01-265bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A200300-002CLONIDINE HYDROCHLORIDE5MG/10ML (0.5MG/ML)INJECTABLE / INJECTIONAPRS2011-01-265bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A200300-001CLONIDINE HYDROCHLORIDE1MG/10ML (0.1MG/ML)INJECTABLE / INJECTIONAP2011-01-26d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A200300-002CLONIDINE HYDROCHLORIDE5MG/10ML (0.5MG/ML)INJECTABLE / INJECTIONAPRS2011-01-26d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A200300-001CLONIDINE HYDROCHLORIDE1MG/10ML (0.1MG/ML)INJECTABLE / INJECTIONAP2011-01-26d06236e962d9…
2024-10-29 15:01 UTC2024-10A200300-002CLONIDINE HYDROCHLORIDE5MG/10ML (0.5MG/ML)INJECTABLE / INJECTIONAPRS2011-01-26d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A200300-001CLONIDINE HYDROCHLORIDE1MG/10ML (0.1MG/ML)INJECTABLE / INJECTIONAP2011-01-2679d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A200300-002CLONIDINE HYDROCHLORIDE5MG/10ML (0.5MG/ML)INJECTABLE / INJECTIONAPRS2011-01-2679d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A200300-001CLONIDINE HYDROCHLORIDE1MG/10ML (0.1MG/ML)INJECTABLE / INJECTIONAP2011-01-26301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A200300-002CLONIDINE HYDROCHLORIDE5MG/10ML (0.5MG/ML)INJECTABLE / INJECTIONAPRS2011-01-26301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A200300-001CLONIDINE HYDROCHLORIDE1MG/10ML (0.1MG/ML)INJECTABLE / INJECTIONAP2011-01-261e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A200300-002CLONIDINE HYDROCHLORIDE5MG/10ML (0.5MG/ML)INJECTABLE / INJECTIONAPRS2011-01-261e350fbaab3a…
2024-05-31 18:47 UTC2024-05A200300-001CLONIDINE HYDROCHLORIDE1MG/10ML (0.1MG/ML)INJECTABLE / INJECTIONAP2011-01-268072bd15b7f6…
2024-05-31 18:47 UTC2024-05A200300-002CLONIDINE HYDROCHLORIDE5MG/10ML (0.5MG/ML)INJECTABLE / INJECTIONAPRS2011-01-268072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A200300-001CLONIDINE HYDROCHLORIDE1MG/10ML (0.1MG/ML)INJECTABLE / INJECTIONAP2011-01-265c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A200300-002CLONIDINE HYDROCHLORIDE5MG/10ML (0.5MG/ML)INJECTABLE / INJECTIONAPRS2011-01-265c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A200300-001CLONIDINE HYDROCHLORIDE1MG/10ML (0.1MG/ML)INJECTABLE / INJECTIONAP2011-01-265d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A200300-002CLONIDINE HYDROCHLORIDE5MG/10ML (0.5MG/ML)INJECTABLE / INJECTIONAPRS2011-01-265d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A200300-001CLONIDINE HYDROCHLORIDE1MG/10ML (0.1MG/ML)INJECTABLE / INJECTIONAP2011-01-264b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A200300-002CLONIDINE HYDROCHLORIDE5MG/10ML (0.5MG/ML)INJECTABLE / INJECTIONAPRS2011-01-264b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A200300-001CLONIDINE HYDROCHLORIDE1MG/10ML (0.1MG/ML)INJECTABLE / INJECTIONAP2011-01-2674a2ff9319b5…
2019-12-13 00:20 UTC2019-12A200300-002CLONIDINE HYDROCHLORIDE5MG/10ML (0.5MG/ML)INJECTABLE / INJECTIONAP2011-01-2674a2ff9319b5…
2022-03-09 01:35 UTC2022-03A200300-001CLONIDINE HYDROCHLORIDE1MG/10ML (0.1MG/ML)INJECTABLE / INJECTIONAP2011-01-26bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A200300-002CLONIDINE HYDROCHLORIDE5MG/10ML (0.5MG/ML)INJECTABLE / INJECTIONAPRS2011-01-26bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A200300-001CLONIDINE HYDROCHLORIDE1MG/10ML (0.1MG/ML)INJECTABLE / INJECTIONAP2011-01-26782e0a99824c…
2021-12-28 21:50 UTC2021-12A200300-002CLONIDINE HYDROCHLORIDE5MG/10ML (0.5MG/ML)INJECTABLE / INJECTIONAPRS2011-01-26782e0a99824c…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A200300-001AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A200300-002AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A200300-001AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A200300-002AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A200300-001AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A200300-002AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A200300-001AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A200300-002AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A200300-001AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A200300-002AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A200300-001AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A200300-002AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A200300-001AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A200300-002AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A200300-001AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A200300-002AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A200300-001AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A200300-002AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A200300-001AP1d06236e962d9…
2024-10-29 15:01 UTC2024-10A200300-002AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A200300-001AP179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A200300-002AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A200300-001AP1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A200300-002AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A200300-001AP11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A200300-002AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A200300-001AP18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A200300-002AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A200300-001AP15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A200300-002AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A200300-001AP15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A200300-002AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A200300-001AP14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A200300-002AP14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A200300-001AP174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A200300-002AP174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A200300-001AP1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A200300-002AP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A200300-001AP1782e0a99824c…
2021-12-28 21:50 UTC2021-12A200300-002AP1782e0a99824c…

Additional Listing Data#

Finished product
Yes
Brand name base
CLONIDINE HCI
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
CLONIDINE HYDROCHLORIDE100 ug/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
W76I6XXF06Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
884221Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
7daa1996-ea9f-2576-e053-2991aa0a6be5Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
45c8ba14-e378-46f0-b21f-1aad8e08c613Product name120250221
6920b0ed-30bc-b127-73e1-0713049bd41eProduct name920190618
6920b0ed-30bc-b127-73e1-0713049bd41eProduct name520171212
48f5a4fd-7cdc-dc04-771d-ce7a47326789Product name220150123
624cf764-e200-44b5-83c2-84526255adb5Product name120150107
47972e1b-c905-eeee-5e77-eb4538ad833cProduct name120140508
7667d8e2-e5be-36e1-4de7-231aa7fdaf5cProduct name120140508

FDA-Initiated Inactive NDC Indexing#

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
51662-1346-1CLONIDINE HCI10 mL in 1 VIAL, SINGLE-USEINJECTION, SOLUTION104
51662-1346-1CLONIDINE HCI1 in 1 BOXINJECTION, SOLUTION14

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
51662-1346CLONIDINE HCI INJECTION, SOLUTION [HF ACQUISITION CO LLC, DBA HEALTHFIRST]4Current NDC, Legacy NDC, 2 package rows20221211_7daa1996-ea9f-2576-e053-2991aa0a6be5.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
CLONIDINE HCICLONIDINE HCIHF Acquisition Co LLC, DBA HealthFirst7daa1996-ea9f-2576-e053-2991aa0a6be52022-12-09Warnings, Adverse reactionsExact identifier
application applno (ANDA): 200300
application number: ANDA200300
ndc (product): 51662-1346
Clonidine HydrochlorideCLONIDINE HYDROCHLORIDEHikma Pharmaceuticals USA Inc.2a5b46ec-4c16-48a5-9e58-8d28a3f212742022-06-27Warnings, Adverse reactionsExact identifier
application applno (ANDA): 200300
application number: ANDA200300

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
884221cloNIDine HCl 1000 MCG in 10 ML InjectionPSN7daa1996-ea9f-2576-e053-2991aa0a6be54
88422110 ML clonidine hydrochloride 0.1 MG/ML InjectionSCD7daa1996-ea9f-2576-e053-2991aa0a6be54
884221clonidine HCl 1000 MCG per 10 ML InjectionSY7daa1996-ea9f-2576-e053-2991aa0a6be54

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
51662-1346-1516621346011 VIAL, SINGLE-USE in 1 BOX (51662-1346-1) / 10 mL in 1 VIAL, SINGLE-USE2018-12-230000-00-00NoNoCurrent