sertraline HCl

Product NDC
52427-664
11-digit product format
524270664
Labeler code
52427
Product ID
52427-664_fee38eb1-855e-a3c0-c707-8665f61fb400
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
sertraline hydrochloride
Dosage form
CAPSULE
Route
ORAL
Labeler
Almatica Pharma LLC
Application
NDA215133
Marketing category
NDA
Marketing start
2021-10-04
Substance
SERTRALINE HYDROCHLORIDE
Active strength
150 mg/1
Pharmacologic classes
Cytochrome P450 2D6 Inhibitors [MoA], Serotonin Reuptake Inhibitor [EPC], Serotonin Uptake Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N215133-001SERTRALINE HYDROCHLORIDESERTRALINE HYDROCHLORIDEEQ 150MG BASECAPSULE / ORALABRLD, RS2021-10-04
N215133-002SERTRALINE HYDROCHLORIDESERTRALINE HYDROCHLORIDEEQ 200MG BASECAPSULE / ORALABRLD2021-10-04

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
N215133-001AB
N215133-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 66 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N215133-001SERTRALINE HYDROCHLORIDEEQ 150MG BASECAPSULE / ORALABRLD, RS2021-10-04011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215133-002SERTRALINE HYDROCHLORIDEEQ 200MG BASECAPSULE / ORALABRLD2021-10-04011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215133-001SERTRALINE HYDROCHLORIDEEQ 150MG BASECAPSULE / ORALABRLD, RS2021-10-0431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215133-002SERTRALINE HYDROCHLORIDEEQ 200MG BASECAPSULE / ORALABRLD2021-10-0431067a03dcf5…
2025-08-23 18:47 UTC2025-08N215133-001SERTRALINE HYDROCHLORIDEEQ 150MG BASECAPSULE / ORALABRLD, RS2021-10-046a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215133-002SERTRALINE HYDROCHLORIDEEQ 200MG BASECAPSULE / ORALABRLD2021-10-046a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215133-001SERTRALINE HYDROCHLORIDEEQ 150MG BASECAPSULE / ORALRLD, RS2021-10-04fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215133-002SERTRALINE HYDROCHLORIDEEQ 200MG BASECAPSULE / ORALRLD2021-10-04fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N215133-001SERTRALINE HYDROCHLORIDEEQ 150MG BASECAPSULE / ORALRLD, RS2021-10-04b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N215133-002SERTRALINE HYDROCHLORIDEEQ 200MG BASECAPSULE / ORALRLD2021-10-04b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N215133-001SERTRALINE HYDROCHLORIDEEQ 150MG BASECAPSULE / ORALRLD, RS2021-10-0403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N215133-002SERTRALINE HYDROCHLORIDEEQ 200MG BASECAPSULE / ORALRLD2021-10-0403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N215133-001SERTRALINE HYDROCHLORIDEEQ 150MG BASECAPSULE / ORALRLD, RS2021-10-042680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N215133-002SERTRALINE HYDROCHLORIDEEQ 200MG BASECAPSULE / ORALRLD2021-10-042680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N215133-001SERTRALINE HYDROCHLORIDEEQ 150MG BASECAPSULE / ORALRLD, RS2021-10-045bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N215133-002SERTRALINE HYDROCHLORIDEEQ 200MG BASECAPSULE / ORALRLD2021-10-045bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N215133-001SERTRALINE HYDROCHLORIDEEQ 150MG BASECAPSULE / ORALRLD, RS2021-10-04d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N215133-002SERTRALINE HYDROCHLORIDEEQ 200MG BASECAPSULE / ORALRLD2021-10-04d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N215133-001SERTRALINE HYDROCHLORIDEEQ 150MG BASECAPSULE / ORALRLD, RS2021-10-04d06236e962d9…
2024-10-29 15:01 UTC2024-10N215133-002SERTRALINE HYDROCHLORIDEEQ 200MG BASECAPSULE / ORALRLD2021-10-04d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N215133-001SERTRALINE HYDROCHLORIDEEQ 150MG BASECAPSULE / ORALRLD, RS2021-10-0479d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N215133-002SERTRALINE HYDROCHLORIDEEQ 200MG BASECAPSULE / ORALRLD2021-10-0479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N215133-001SERTRALINE HYDROCHLORIDEEQ 150MG BASECAPSULE / ORALRLD, RS2021-10-04301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N215133-002SERTRALINE HYDROCHLORIDEEQ 200MG BASECAPSULE / ORALRLD2021-10-04301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N215133-001SERTRALINE HYDROCHLORIDEEQ 150MG BASECAPSULE / ORALRLD, RS2021-10-041e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N215133-002SERTRALINE HYDROCHLORIDEEQ 200MG BASECAPSULE / ORALRLD2021-10-041e350fbaab3a…
2024-05-31 18:47 UTC2024-05N215133-001SERTRALINE HYDROCHLORIDEEQ 150MG BASECAPSULE / ORALRLD, RS2021-10-048072bd15b7f6…
2024-05-31 18:47 UTC2024-05N215133-002SERTRALINE HYDROCHLORIDEEQ 200MG BASECAPSULE / ORALRLD2021-10-048072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N215133-001SERTRALINE HYDROCHLORIDEEQ 150MG BASECAPSULE / ORALRLD2021-10-045c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N215133-002SERTRALINE HYDROCHLORIDEEQ 200MG BASECAPSULE / ORALRLD, RS2021-10-045c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N215133-001SERTRALINE HYDROCHLORIDEEQ 150MG BASECAPSULE / ORALRLD2021-10-045d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N215133-002SERTRALINE HYDROCHLORIDEEQ 200MG BASECAPSULE / ORALRLD, RS2021-10-045d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N215133-001SERTRALINE HYDROCHLORIDEEQ 150MG BASECAPSULE / ORALRLD2021-10-044b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N215133-002SERTRALINE HYDROCHLORIDEEQ 200MG BASECAPSULE / ORALRLD, RS2021-10-044b0b4de00fa7…
2022-03-09 01:35 UTC2022-03N215133-001SERTRALINE HYDROCHLORIDEEQ 150MG BASECAPSULE / ORALRLD2021-10-04bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N215133-002SERTRALINE HYDROCHLORIDEEQ 200MG BASECAPSULE / ORALRLD, RS2021-10-04bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N215133-001SERTRALINE HYDROCHLORIDEEQ 150MG BASECAPSULE / ORALRLD2021-10-04782e0a99824c…
2021-12-28 21:50 UTC2021-12N215133-002SERTRALINE HYDROCHLORIDEEQ 200MG BASECAPSULE / ORALRLD, RS2021-10-04782e0a99824c…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N215133-001SERTRALINE HYDROCHLORIDEEQ 150MG BASECAPSULE / ORALRLD, RS2021-10-046a51e52b5d6a…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N215133-002SERTRALINE HYDROCHLORIDEEQ 200MG BASECAPSULE / ORALRLD2021-10-046a51e52b5d6a…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N215133-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215133-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215133-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215133-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N215133-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215133-002AB16a471c1ec25d…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N215133-001AB1a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N215133-002AB1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
sertraline HCl
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
SERTRALINE HYDROCHLORIDE150 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
UTI8907Y6XInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
251201Internal RxNorm lookup
410584Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
8c8bcba9-eaeb-aa44-f9ea-b580de55a439Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
4ac594ea-ad8b-47fd-9b52-bbd98301675eProduct name120220317
255fa467-900b-5557-4215-6823352d1150Product name220211028

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
52427-664-30sertraline HCl30 in 1 BOTTLECAPSULE305

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
52427-664-30EA - Each52427-6648f4dda60-99f6-4aad-9e69-22da4151836012021-11-09

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
52427-664SERTRALINE HCL (SERTRALINE HYDROCHLORIDE) CAPSULE [ALMATICA PHARMA LLC]4Current NDC, Legacy NDC, 1 package rows20241011_8c8bcba9-eaeb-aa44-f9ea-b580de55a439.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
sertraline hydrochlorideSERTRALINE HYDROCHLORIDEAlvogen, Inc.e0e1f35e-114d-bb39-34f1-70208b94ac9e2025-08-06Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 215133
application number: NDA215133
sertraline HClSERTRALINE HYDROCHLORIDEAlmatica Pharma LLC8c8bcba9-eaeb-aa44-f9ea-b580de55a4392023-08-24Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 215133
application number: NDA215133
ndc (product): 52427-664

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
410584sertraline 150 MG Oral CapsulePSN8c8bcba9-eaeb-aa44-f9ea-b580de55a4395
410584sertraline 150 MG Oral CapsuleSCD8c8bcba9-eaeb-aa44-f9ea-b580de55a4395
251201sertraline 200 MG Oral CapsuleSCD8c8bcba9-eaeb-aa44-f9ea-b580de55a4395
410584sertraline 150 MG (as sertraline HCl 168 MG) Oral CapsuleSY8c8bcba9-eaeb-aa44-f9ea-b580de55a4395
251201sertraline 200 MG (as sertraline HCl 224 MG) Oral CapsuleSY8c8bcba9-eaeb-aa44-f9ea-b580de55a4395

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
52427-664-305242706643030 CAPSULE in 1 BOTTLE (52427-664-30) 30 capsule2021-11-010000-00-00NoNoCurrent