EPANED

Product NDC
52652-1001
Requested package NDC
52652-1001-1
11-digit product format
526521001
Labeler code
52652
Product ID
52652-1001_ee51b792-c85d-49ad-9cc0-6d13b10691e4
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
enalapril maleate
Dosage form
KIT
Labeler
Silvergate Pharmaceuticals, Inc.
Application
NDA204308
Marketing category
NDA
Marketing start
2013-08-22
Marketing end
0000-00-00
Active strength
0
NDC exclude flag
No
Listing certified through
2021-12-31
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 1 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded packagepackage52652-100152652-1001-1DDiscontinued by firm2026-08-17

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 12 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Snapshot, Source SHA-256 table
Captured / source dateSnapshotSource SHA-256
2025-12-14 17:58 UTC · source 2025-12-05d630ba8d3edf…732f749b63fb…
2025-08-27 00:01 UTC · source 2025-08-26f5e01cc5f278…a2eaf40c39c3…
2025-04-01 02:39 UTC · source 2025-03-312ef7874e63bc…57b86245f4fa…
2025-03-28 20:22 UTC · source 2025-03-28a1b67e2a42f9…c4cf2c586c0d…
2025-03-22 03:12 UTC · source 2025-03-21cfe11265f3b6…090c488252e2…
2025-03-10 12:48 UTC · source 2025-03-10cdf11ea48f46…ba0047e9e063…
2025-02-02 03:52 UTC · source 2025-01-31302b2466d912…e7b80fea0513…
2025-01-20 13:05 UTC · source 2025-01-20ed331223b511…672a5bd82f5f…
2025-01-11 03:41 UTC · source 2025-01-100efc9e666f02…f202fb6c5f17…
2024-11-09 02:27 UTC · source 2024-11-08ad56d346431e…cc804d4bbf1e…
2024-10-04 04:10 UTC · source 2024-10-03367a005e9d99…383a685ebd0f…
2024-07-10 04:00 UTC · source 2024-07-09557ba5c1ecfa…9c80585c8c6e…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N204308-001EPANED KITENALAPRIL MALEATE1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13

Orange Book patents#

Current patent rows page 1 of 1 · 12 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N204308-00185687472032-11-06Drug product2013-10-31
N204308-00187783662032-11-06U-17232014-07-16
N204308-00187783662032-11-06U-1852014-07-16
N204308-00187783662032-11-06U-18922014-07-16
N204308-00187783662032-11-06U-32014-07-16
N204308-00187783662032-11-06U-712014-07-16
N204308-00198552142032-11-06Drug product2018-01-10
N204308-00199685532032-11-06U-17232018-06-01
N204308-00199685532032-11-06U-1852018-06-01
N204308-00199685532032-11-06U-18922018-06-01
N204308-00199685532032-11-06U-32018-06-01
N204308-00199685532032-11-06U-712018-06-01

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-1331067a03dcf5…
2025-08-23 18:47 UTC2025-08N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-136a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-1303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-132680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-135bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-1379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-131e350fbaab3a…
2024-05-31 18:47 UTC2024-05N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-138072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-135c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N204308-001EPANED KIT1MG/MLFOR SOLUTION / ORALRLD2013-08-135d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N204308-001EPANED KIT1MG/MLFOR SOLUTION / ORALRLD2013-08-134b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N204308-001EPANED KIT1MG/MLFOR SOLUTION / ORALRLD2013-08-1374a2ff9319b5…
2022-03-09 01:35 UTC2022-03N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**FOR SOLUTION / ORALRLD2013-08-13782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N204308-001EPANED KIT1MG/MLFOR SOLUTION / ORALRLD2013-08-1387673890dc5c…
2021-03-12 10:30 UTC2021-03N204308-001EPANED KIT1MG/MLFOR SOLUTION / ORALRLD2013-08-135aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N204308-001EPANED KIT1MG/MLFOR SOLUTION / ORALRLD2013-08-138869cabd3fbd…
2020-11-12 02:37 UTC2020-11N204308-001EPANED KIT1MG/MLFOR SOLUTION / ORALRLD2013-08-13c0c555d07b60…
2019-12-14 00:12 UTC2019-12N204308-001EPANED KIT1MG/MLFOR SOLUTION / ORALRLD2013-08-133f01610625f2…
2019-09-15 20:21 UTC2019-09N204308-001EPANED KIT1MG/MLFOR SOLUTION / ORALRLD2013-08-13b00525d2431f…
2019-07-19 19:46 UTC2019-07N204308-001EPANED KIT1MG/MLFOR SOLUTION / ORALRLD2013-08-13ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-136a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-131c564ffb4f44…
2023-12-20 04:57 UTC2023-12N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-139b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-133f0d92c62455…
2023-05-13 08:27 UTC2023-05N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13053a50430f4f…
2023-01-26 05:58 UTC2023-01N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-133bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-133a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13e64feba35796…

Observed Orange Book patent history#

Patent history page 1 of 13 · 504 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-08-18 06:07:402026-07N204308-00185687472032-11-06Drug product2013-10-31caaa826d4ba7…
2026-08-18 06:07:402026-07N204308-00187783662032-11-06U-32014-07-16caaa826d4ba7…
2026-08-18 06:07:402026-07N204308-00187783662032-11-06U-712014-07-16caaa826d4ba7…
2026-08-18 06:07:402026-07N204308-00187783662032-11-06U-1852014-07-16caaa826d4ba7…
2026-08-18 06:07:402026-07N204308-00187783662032-11-06U-17232014-07-16caaa826d4ba7…
2026-08-18 06:07:402026-07N204308-00187783662032-11-06U-18922014-07-16caaa826d4ba7…
2026-08-18 06:07:402026-07N204308-00198552142032-11-06Drug product2018-01-10caaa826d4ba7…
2026-08-18 06:07:402026-07N204308-00199685532032-11-06U-712018-06-01caaa826d4ba7…
2026-08-18 06:07:402026-07N204308-00199685532032-11-06U-32018-06-01caaa826d4ba7…
2026-08-18 06:07:402026-07N204308-00199685532032-11-06U-18922018-06-01caaa826d4ba7…
2026-08-18 06:07:402026-07N204308-00199685532032-11-06U-1852018-06-01caaa826d4ba7…
2026-08-18 06:07:402026-07N204308-00199685532032-11-06U-17232018-06-01caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N204308-00185687472032-11-06Drug product2013-10-31011fe1cb6892…
2026-02-19 14:30 UTC2026-02N204308-00187783662032-11-06U-32014-07-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N204308-00187783662032-11-06U-712014-07-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N204308-00187783662032-11-06U-1852014-07-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N204308-00187783662032-11-06U-17232014-07-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N204308-00187783662032-11-06U-18922014-07-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N204308-00198552142032-11-06Drug product2018-01-10011fe1cb6892…
2026-02-19 14:30 UTC2026-02N204308-00199685532032-11-06U-712018-06-01011fe1cb6892…
2026-02-19 14:30 UTC2026-02N204308-00199685532032-11-06U-32018-06-01011fe1cb6892…
2026-02-19 14:30 UTC2026-02N204308-00199685532032-11-06U-18922018-06-01011fe1cb6892…
2026-02-19 14:30 UTC2026-02N204308-00199685532032-11-06U-1852018-06-01011fe1cb6892…
2026-02-19 14:30 UTC2026-02N204308-00199685532032-11-06U-17232018-06-01011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N204308-00185687472032-11-06Drug product2013-10-3131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N204308-00187783662032-11-06U-32014-07-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N204308-00187783662032-11-06U-712014-07-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N204308-00187783662032-11-06U-1852014-07-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N204308-00187783662032-11-06U-17232014-07-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N204308-00187783662032-11-06U-18922014-07-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N204308-00198552142032-11-06Drug product2018-01-1031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N204308-00199685532032-11-06U-712018-06-0131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N204308-00199685532032-11-06U-32018-06-0131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N204308-00199685532032-11-06U-18922018-06-0131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N204308-00199685532032-11-06U-1852018-06-0131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N204308-00199685532032-11-06U-17232018-06-0131067a03dcf5…
2025-08-23 18:47 UTC2025-08N204308-00185687472032-11-06Drug product2013-10-316a471c1ec25d…
2025-08-23 18:47 UTC2025-08N204308-00187783662032-11-06U-32014-07-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N204308-00187783662032-11-06U-712014-07-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N204308-00187783662032-11-06U-1852014-07-166a471c1ec25d…

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
52652-1001-1ML - Milliliter52652-1001e78d25a3-cc1c-465f-b639-6f5864a1e2c412013-09-04

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
ENALAPRIL MALEATEACTIVE INGREDIENT9O25354EPJEPANED (ENALAPRIL MALEATE) KIT [SILVERGATE PHARMACEUTICALS, INC.]3
ENALAPRILAT ANHYDROUSACTIVE MOIETYQ508Q118JMEPANED (ENALAPRIL MALEATE) KIT [SILVERGATE PHARMACEUTICALS, INC.]3
CITRIC ACID MONOHYDRATEINACTIVE INGREDIENT2968PHW8QPEPANED (ENALAPRIL MALEATE) KIT [SILVERGATE PHARMACEUTICALS, INC.]3
GLYCERININACTIVE INGREDIENTPDC6A3C0OXEPANED (ENALAPRIL MALEATE) KIT [SILVERGATE PHARMACEUTICALS, INC.]3
MANNITOLINACTIVE INGREDIENT3OWL53L36AEPANED (ENALAPRIL MALEATE) KIT [SILVERGATE PHARMACEUTICALS, INC.]3
METHYLPARABENINACTIVE INGREDIENTA2I8C7HI9TEPANED (ENALAPRIL MALEATE) KIT [SILVERGATE PHARMACEUTICALS, INC.]3
POTASSIUM SORBATEINACTIVE INGREDIENT1VPU26JZZ4EPANED (ENALAPRIL MALEATE) KIT [SILVERGATE PHARMACEUTICALS, INC.]3
PROPYLPARABENINACTIVE INGREDIENTZ8IX2SC1OHEPANED (ENALAPRIL MALEATE) KIT [SILVERGATE PHARMACEUTICALS, INC.]3
SACCHARIN SODIUMINACTIVE INGREDIENTSB8ZUX40TYEPANED (ENALAPRIL MALEATE) KIT [SILVERGATE PHARMACEUTICALS, INC.]3
SILICON DIOXIDEINACTIVE INGREDIENTETJ7Z6XBU4EPANED (ENALAPRIL MALEATE) KIT [SILVERGATE PHARMACEUTICALS, INC.]3
SODIUM CITRATEINACTIVE INGREDIENT1Q73Q2JULREPANED (ENALAPRIL MALEATE) KIT [SILVERGATE PHARMACEUTICALS, INC.]3
SORBITOLINACTIVE INGREDIENT506T60A25REPANED (ENALAPRIL MALEATE) KIT [SILVERGATE PHARMACEUTICALS, INC.]3
WATERINACTIVE INGREDIENT059QF0KO0REPANED (ENALAPRIL MALEATE) KIT [SILVERGATE PHARMACEUTICALS, INC.]3
XANTHAN GUMINACTIVE INGREDIENTTTV12P4NEEEPANED (ENALAPRIL MALEATE) KIT [SILVERGATE PHARMACEUTICALS, INC.]3

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
52652-1001-1526521001011 KIT in 1 CARTON (52652-1001-1) * 150 mL in 1 BOTTLE * 150 mL in 1 BOTTLE1 kit2013-08-220000-00-00NoNoCurrent