Eprontia

Product NDC
52652-9001
11-digit product format
526529001
Labeler code
52652
Product ID
52652-9001_3feb6452-372c-4c60-8e91-220be75f90b1
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Topiramate
Dosage form
SOLUTION
Route
ORAL
Labeler
Azurity Pharmaceuticals, Inc.
Application
NDA214679
Marketing category
NDA
Marketing start
2021-12-06
Substance
TOPIRAMATE
Active strength
25 mg/mL
Pharmacologic classes
Cytochrome P450 2C19 Inhibitors [MoA], Cytochrome P450 3A4 Inducers [MoA], Decreased Central Nervous System Disorganized Electrical Activity [PE]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N214679-001EPRONTIATOPIRAMATE25MG/MLSOLUTION / ORALABRLD, RS2021-11-05

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
N214679-001AB

Orange Book patents#

Current patent rows page 1 of 1 · 11 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N214679-001114330462040-08-21U-34132022-09-13
N214679-001114330462040-08-21U-34142022-09-13
N214679-001114330462040-08-21U-34152022-09-13
N214679-001116333742040-08-21Drug product2023-04-27
N214679-001118263432040-08-21Drug product2023-12-11
N214679-001119113622040-08-21U-3413Drug product2024-03-12
N214679-001119113622040-08-21U-3414Drug product2024-03-12
N214679-001119113622040-08-21U-3415Drug product2024-03-12
N214679-001122905032040-08-21U-3413Drug product2025-05-16
N214679-001122905032040-08-21U-3414Drug product2025-05-16
N214679-001122905032040-08-21U-3415Drug product2025-05-16

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N214679-001EPRONTIA25MG/MLSOLUTION / ORALABRLD, RS2021-11-05011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214679-001EPRONTIA25MG/MLSOLUTION / ORALABRLD, RS2021-11-0531067a03dcf5…
2025-08-23 18:47 UTC2025-08N214679-001EPRONTIA25MG/MLSOLUTION / ORALABRLD, RS2021-11-056a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N214679-001EPRONTIA25MG/MLSOLUTION / ORALABRLD, RS2021-11-05fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N214679-001EPRONTIA25MG/MLSOLUTION / ORALABRLD, RS2021-11-05b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N214679-001EPRONTIA25MG/MLSOLUTION / ORALABRLD, RS2021-11-0503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N214679-001EPRONTIA25MG/MLSOLUTION / ORALABRLD, RS2021-11-052680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N214679-001EPRONTIA25MG/MLSOLUTION / ORALRLD, RS2021-11-055bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N214679-001EPRONTIA25MG/MLSOLUTION / ORALABRLD, RS2021-11-05d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N214679-001EPRONTIA25MG/MLSOLUTION / ORALRLD, RS2021-11-05d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N214679-001EPRONTIA25MG/MLSOLUTION / ORALRLD, RS2021-11-0579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N214679-001EPRONTIA25MG/MLSOLUTION / ORALRLD, RS2021-11-05301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N214679-001EPRONTIA25MG/MLSOLUTION / ORALRLD, RS2021-11-051e350fbaab3a…
2024-05-31 18:47 UTC2024-05N214679-001EPRONTIA25MG/MLSOLUTION / ORALRLD, RS2021-11-058072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N214679-001EPRONTIA25MG/MLSOLUTION / ORALRLD, RS2021-11-055c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N214679-001EPRONTIA25MG/MLSOLUTION / ORALRLD, RS2021-11-055d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N214679-001EPRONTIA25MG/MLSOLUTION / ORALRLD, RS2021-11-054b0b4de00fa7…
2022-03-09 01:35 UTC2022-03N214679-001EPRONTIA25MG/MLSOLUTION / ORALRLD, RS2021-11-05bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N214679-001EPRONTIA25MG/MLSOLUTION / ORALRLD, RS2021-11-05782e0a99824c…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N214679-001EPRONTIA25MG/MLSOLUTION / ORALRLD, RS2021-11-056a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N214679-001EPRONTIA25MG/MLSOLUTION / ORALRLD, RS2021-11-051c564ffb4f44…
2023-12-20 04:57 UTC2023-12N214679-001EPRONTIA25MG/MLSOLUTION / ORALRLD, RS2021-11-05ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N214679-001EPRONTIA25MG/MLSOLUTION / ORALRLD, RS2021-11-05a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N214679-001EPRONTIA25MG/MLSOLUTION / ORALRLD, RS2021-11-059b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N214679-001EPRONTIA25MG/MLSOLUTION / ORALRLD, RS2021-11-05a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N214679-001EPRONTIA25MG/MLSOLUTION / ORALRLD, RS2021-11-053f0d92c62455…
2023-05-13 08:27 UTC2023-05N214679-001EPRONTIA25MG/MLSOLUTION / ORALRLD, RS2021-11-05053a50430f4f…
2023-01-26 05:58 UTC2023-01N214679-001EPRONTIA25MG/MLSOLUTION / ORALRLD, RS2021-11-053bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N214679-001EPRONTIA25MG/MLSOLUTION / ORALRLD, RS2021-11-053a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N214679-001EPRONTIA25MG/MLSOLUTION / ORALRLD, RS2021-11-05f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N214679-001EPRONTIA25MG/MLSOLUTION / ORALRLD, RS2021-11-05e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N214679-001EPRONTIA25MG/MLSOLUTION / ORALRLD, RS2021-11-05cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N214679-001EPRONTIA25MG/MLSOLUTION / ORALABRLD, RS2021-11-05a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N214679-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214679-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N214679-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N214679-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N214679-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N214679-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N214679-001AB12680178bc6a6…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N214679-001AB1d8e5a09893c0…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N214679-001AB1a50c72e98297…

Observed Orange Book patent history#

Patent history page 1 of 5 · 174 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N214679-001114330462040-08-21U-34132022-09-13011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214679-001114330462040-08-21U-34142022-09-13011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214679-001114330462040-08-21U-34152022-09-13011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214679-001116333742040-08-21Drug product2023-04-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214679-001118263432040-08-21Drug product2023-12-11011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214679-001119113622040-08-21U-3413Drug product2024-03-12011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214679-001119113622040-08-21U-3414Drug product2024-03-12011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214679-001119113622040-08-21U-3415Drug product2024-03-12011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214679-001122905032040-08-21U-3413Drug product2025-05-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214679-001122905032040-08-21U-3415Drug product2025-05-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214679-001122905032040-08-21U-3414Drug product2025-05-16011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214679-001114330462040-08-21U-34132022-09-1331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214679-001114330462040-08-21U-34142022-09-1331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214679-001114330462040-08-21U-34152022-09-1331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214679-001116333742040-08-21Drug product2023-04-2731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214679-001118263432040-08-21Drug product2023-12-1131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214679-001119113622040-08-21U-3413Drug product2024-03-1231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214679-001119113622040-08-21U-3414Drug product2024-03-1231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214679-001119113622040-08-21U-3415Drug product2024-03-1231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214679-001122905032040-08-21U-3413Drug product2025-05-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214679-001122905032040-08-21U-3415Drug product2025-05-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214679-001122905032040-08-21U-3414Drug product2025-05-1631067a03dcf5…
2025-08-23 18:47 UTC2025-08N214679-001114330462040-08-21U-34132022-09-136a471c1ec25d…
2025-08-23 18:47 UTC2025-08N214679-001114330462040-08-21U-34142022-09-136a471c1ec25d…
2025-08-23 18:47 UTC2025-08N214679-001114330462040-08-21U-34152022-09-136a471c1ec25d…
2025-08-23 18:47 UTC2025-08N214679-001116333742040-08-21Drug product2023-04-276a471c1ec25d…
2025-08-23 18:47 UTC2025-08N214679-001118263432040-08-21Drug product2023-12-116a471c1ec25d…
2025-08-23 18:47 UTC2025-08N214679-001119113622040-08-21U-3413Drug product2024-03-126a471c1ec25d…
2025-08-23 18:47 UTC2025-08N214679-001119113622040-08-21U-3414Drug product2024-03-126a471c1ec25d…
2025-08-23 18:47 UTC2025-08N214679-001119113622040-08-21U-3415Drug product2024-03-126a471c1ec25d…
2025-08-23 18:47 UTC2025-08N214679-001122905032040-08-21U-3413Drug product2025-05-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N214679-001122905032040-08-21U-3415Drug product2025-05-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N214679-001122905032040-08-21U-3414Drug product2025-05-166a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N214679-001114330462040-08-21U-34132022-09-13fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N214679-001114330462040-08-21U-34142022-09-13fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N214679-001114330462040-08-21U-34152022-09-13fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N214679-001116333742040-08-21Drug product2023-04-27fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N214679-001118263432040-08-21Drug product2023-12-11fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N214679-001119113622040-08-21U-3413Drug product2024-03-12fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N214679-001119113622040-08-21U-3414Drug product2024-03-12fd3edfee7708…

Additional Listing Data#

Finished product
Yes
Brand name base
Eprontia
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
TOPIRAMATE25 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
0H73WJJ391Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2586427Internal RxNorm lookup
2586433Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
e2a4df59-fead-4a01-9021-9eda02c48010Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
e5b1b0ba-27f8-4d5d-8943-8aed080fdedcProduct name420260306
6c26dd6d-01b5-4a80-b096-b3a6f7ca6077Product name220250623
cb966f54-bbf0-40fb-b581-80c6648d510cProduct name420250623
6e2fb0d7-40d7-e97c-1375-fa022ff20193Product name420250305
3d272a3f-17c0-421d-bc43-3cbdb719258dProduct name120250303

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
52652-9001-1Eprontia473 mL in 1 BOTTLESOLUTION4738
52652-9001-2Eprontia1 in 1 CARTONSOLUTION18
52652-9001-2Eprontia240 mL in 1 BOTTLESOLUTION2408
52652-9001-3Eprontia1 in 1 CARTONSOLUTION18
52652-9001-3Eprontia120 mL in 1 BOTTLESOLUTION1208

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
52652-9001-1ML - Milliliter52652-90012590f13a-932d-4de9-b3c7-44eb1d1223b912021-12-08
52652-9001-2ML - Milliliter52652-9001976f39fb-48c4-457a-82b8-b9b16ff1173c12023-06-06
52652-9001-3ML - Milliliter52652-9001f3070371-41a5-4e3f-b43f-66f33163fe7312023-06-06

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
52652-9001EPRONTIA (TOPIRAMATE) SOLUTION [AZURITY PHARMACEUTICALS, INC.]7Current NDC, Legacy NDC, 5 package rows20250323_e2a4df59-fead-4a01-9021-9eda02c48010.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
EprontiaTOPIRAMATEAzurity Pharmaceuticals, Inc.e2a4df59-fead-4a01-9021-9eda02c480102025-11-13Warnings, Adverse reactionsExact identifier
application applno (NDA): 214679
application number: NDA214679
ndc (product): 52652-9001

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
2586433EPRONTIA 25 MG/mL Oral SolutionPSNe2a4df59-fead-4a01-9021-9eda02c480108
2586427topiramate 25 MG/mL Oral SolutionPSNe2a4df59-fead-4a01-9021-9eda02c480108
2586433topiramate 25 MG/ML Oral Solution [Eprontia]SBDe2a4df59-fead-4a01-9021-9eda02c480108
2586427topiramate 25 MG/ML Oral SolutionSCDe2a4df59-fead-4a01-9021-9eda02c480108
2586433Eprontia 25 MG/ML Oral SolutionSYe2a4df59-fead-4a01-9021-9eda02c480108

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
52652-9001-152652900101473 mL in 1 BOTTLE (52652-9001-1) 473 ml2021-12-060000-00-00NoNoCurrent
52652-9001-2526529001021 BOTTLE in 1 CARTON (52652-9001-2) / 240 mL in 1 BOTTLE1 bottle2023-01-020000-00-00NoNoCurrent
52652-9001-3526529001031 BOTTLE in 1 CARTON (52652-9001-3) / 120 mL in 1 BOTTLE1 bottle2023-01-020000-00-00NoNoCurrent