Prometrium

Product NDC
72989-372
11-digit product format
729890372
Labeler code
72989
Product ID
72989-372_3d2fed08-88a5-4645-b158-33527a2556eb
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Progesterone
Dosage form
CAPSULE
Route
ORAL
Labeler
Acertis Pharmaceuticals, LLC
Application
NDA019781
Marketing category
NDA
Marketing start
2022-11-01
Substance
PROGESTERONE
Active strength
100 mg/1
Pharmacologic classes
Progesterone [CS], Progesterone [EPC]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N019781-001PROMETRIUMPROGESTERONE100MGCAPSULE / ORALABRLD1998-05-14
N019781-002PROMETRIUMPROGESTERONE200MGCAPSULE / ORALABRLD, RS1999-10-15
N019781-003PROMETRIUMPROGESTERONE300MGCAPSULE / ORAL1999-10-15

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
N019781-001AB
N019781-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-14011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019781-002PROMETRIUM200MGCAPSULE / ORALABRLD, RS1999-10-15011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019781-003PROMETRIUM300MGCAPSULE / ORAL1999-10-15011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-1431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019781-002PROMETRIUM200MGCAPSULE / ORALABRLD, RS1999-10-1531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019781-003PROMETRIUM300MGCAPSULE / ORAL1999-10-1531067a03dcf5…
2025-08-23 18:47 UTC2025-08N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-146a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019781-002PROMETRIUM200MGCAPSULE / ORALABRLD, RS1999-10-156a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019781-003PROMETRIUM300MGCAPSULE / ORAL1999-10-156a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-14fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019781-002PROMETRIUM200MGCAPSULE / ORALABRLD, RS1999-10-15fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019781-003PROMETRIUM300MGCAPSULE / ORAL1999-10-15fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-14b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019781-002PROMETRIUM200MGCAPSULE / ORALABRLD, RS1999-10-15b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019781-003PROMETRIUM300MGCAPSULE / ORAL1999-10-15b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-1403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019781-002PROMETRIUM200MGCAPSULE / ORALABRLD, RS1999-10-1503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019781-003PROMETRIUM300MGCAPSULE / ORAL1999-10-1503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-142680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019781-002PROMETRIUM200MGCAPSULE / ORALABRLD, RS1999-10-152680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019781-003PROMETRIUM300MGCAPSULE / ORAL1999-10-152680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-145bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019781-002PROMETRIUM200MGCAPSULE / ORALABRLD, RS1999-10-155bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019781-003PROMETRIUM300MGCAPSULE / ORAL1999-10-155bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-14d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019781-002PROMETRIUM200MGCAPSULE / ORALABRLD, RS1999-10-15d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019781-003PROMETRIUM300MGCAPSULE / ORAL1999-10-15d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-14d06236e962d9…
2024-10-29 15:01 UTC2024-10N019781-002PROMETRIUM200MGCAPSULE / ORALABRLD, RS1999-10-15d06236e962d9…
2024-10-29 15:01 UTC2024-10N019781-003PROMETRIUM300MGCAPSULE / ORAL1999-10-15d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-1479d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019781-002PROMETRIUM200MGCAPSULE / ORALABRLD, RS1999-10-1579d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019781-003PROMETRIUM300MGCAPSULE / ORAL1999-10-1579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-14301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019781-002PROMETRIUM200MGCAPSULE / ORALABRLD, RS1999-10-15301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019781-003PROMETRIUM300MGCAPSULE / ORAL1999-10-15301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-141e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019781-002PROMETRIUM200MGCAPSULE / ORALABRLD, RS1999-10-151e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019781-003PROMETRIUM300MGCAPSULE / ORAL1999-10-151e350fbaab3a…
2024-05-31 18:47 UTC2024-05N019781-001PROMETRIUM100MGCAPSULE / ORALABRLD1998-05-148072bd15b7f6…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N019781-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019781-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019781-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019781-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N019781-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019781-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019781-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019781-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019781-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019781-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019781-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019781-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019781-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019781-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019781-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019781-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019781-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019781-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N019781-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10N019781-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019781-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019781-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019781-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019781-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019781-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019781-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N019781-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05N019781-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N019781-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N019781-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N019781-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N019781-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N019781-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N019781-002AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N019781-001AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12N019781-002AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N019781-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N019781-002AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N019781-001AB1782e0a99824c…
2021-12-28 21:50 UTC2021-12N019781-002AB1782e0a99824c…

Additional Listing Data#

Finished product
Yes
Brand name base
Prometrium
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
PROGESTERONE100 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
4G7DS2Q64YInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 4 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
260243Internal RxNorm lookup
261319Internal RxNorm lookup
262080Internal RxNorm lookup
312641Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1cf237ff-c4f8-4faa-a7aa-77599c856889Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
b46148e2-ee15-98d5-12f0-f5ec8745f6fcProduct name320220927
76820076-f087-4073-b1d1-aa04b361335eProduct name220220921
d3229c1a-4e51-4e04-9b13-00d24fd35242Product name120200821
213f0591-95c1-b398-40b7-08b31f66b026Product name420190206
85b2d644-53b2-f2dc-4dbc-859116ce56c0Product name120140508
d048f0e3-3c40-8816-8c5c-0ca5cd189aacProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
72989-372-30Prometrium30 in 1 BOTTLECAPSULE303

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
72989-372-30EA - Each72989-372b7b377ce-5ef9-4de7-ba3f-20dd3b1d71fb12022-11-07

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
72989-372PROMETRIUM (PROGESTERONE) CAPSULE [ACERTIS PHARMACEUTICALS, LLC]2Current NDC, Legacy NDC, 1 package rows20240312_1cf237ff-c4f8-4faa-a7aa-77599c856889.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
PrometriumPROGESTERONEAcertis Pharmaceuticals, LLC1cf237ff-c4f8-4faa-a7aa-77599c8568892026-07-23Warnings, Adverse reactionsExact identifier
application applno (NDA): 019781
application number: NDA019781
ndc (product): 72989-372

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
260243progesterone 100 MG Oral CapsulePSN1cf237ff-c4f8-4faa-a7aa-77599c8568893
312641progesterone 200 MG Oral CapsulePSN1cf237ff-c4f8-4faa-a7aa-77599c8568893
262080Prometrium 100 MG Oral CapsulePSN1cf237ff-c4f8-4faa-a7aa-77599c8568893
261319Prometrium 200 MG Oral CapsulePSN1cf237ff-c4f8-4faa-a7aa-77599c8568893
262080progesterone 100 MG Oral Capsule [Prometrium]SBD1cf237ff-c4f8-4faa-a7aa-77599c8568893
261319progesterone 200 MG Oral Capsule [Prometrium]SBD1cf237ff-c4f8-4faa-a7aa-77599c8568893
260243progesterone 100 MG Oral CapsuleSCD1cf237ff-c4f8-4faa-a7aa-77599c8568893
312641progesterone 200 MG Oral CapsuleSCD1cf237ff-c4f8-4faa-a7aa-77599c8568893
262080Prometrium 100 MG Oral CapsuleSY1cf237ff-c4f8-4faa-a7aa-77599c8568893
261319Prometrium 200 MG Oral CapsuleSY1cf237ff-c4f8-4faa-a7aa-77599c8568893

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
72989-372-307298903723030 CAPSULE in 1 BOTTLE (72989-372-30) 30 capsule2022-11-010000-00-00NoNoCurrent