Vetrimycin 200 by is a Animal medication manufactured, distributed, or labeled by MWI Veterinary Supply Co, Norbrook Laboratories Limited. Drug facts, warnings, and ingredients follow.
VETone®
Vetrimycin™ 200
(oxytetracycline) 200 mg/mL
Antibiotic
ANADA 200-306, Approved by FDA
Injection
Each mL contains 200 mg of oxytetracycline base as amphoteric oxytetracycline.
For use in beef cattle; dairy cattle; calves, including preruminating (veal) calves; and swine.
For animal use only.
Read Entire Package Insert Carefully Before Using This Product.
Vetrimycin™ 200 (oxytetracycline) is a sterile, ready-to-use solution for the administration of the broad-spectrum antibiotic oxytetracycline by injection.
Vetrimycin™ 200 does not require refrigeration; however, it is recommended that it be stored at 59° to 86°F (15° to 30°C). The antibiotic activity of oxytetracycline is not appreciably diminished in the presence of body fluids, serum, or exudates.
CAUTION: When administered to cattle, muscle discoloration may necessitate trimming of the injection site(s) and surrounding tissues during the dressing procedure.
Discontinue treatment at least 28 days prior to slaughter of cattle and swine. Milk taken from animals during treatment and for 96 hours after the last treatment must not be used for food. Rapid intravenous administration may result in animal collapse. Oxytetracycline should be administered intravenously slowly over a period of at least 5 minutes.
Exceeding the highest recommended dosage level of drug per lb of body weight per day, administering more than the recommended number of treatments, and/or exceeding 10 mL intramuscularly or subcutaneously per injection site in adult beef and dairy cattle, and 5 mL intramuscularly per injection site in adult swine, may result in antibiotic residues beyond the withdrawal period.
Consult your veterinarian prior to administering this product in order to determine the proper treatment required in the event of an adverse reaction. At the first sign of any adverse reaction, discontinue use of the product and seek the advice of your veterinarian. Some of the reactions may be attributed either to anaphylaxis (an allergic reaction) or to cardiovascular collapse of unknown cause.
Shortly after injection, treated animals may have transient hemoglobinuria resulting in darkened urine.
As with all antibiotic preparations, use of this drug may result in overgrowth of nonsusceptible organisms, including fungi. A lack of response by the treated animal, or the development of new signs, may suggest that an overgrowth of nonsusceptible organisms has occurred. If any of these conditions occur, consult your veterinarian.
Since bacteriostatic drugs may interfere with the bactericidal action of penicillin, it is advisable to avoid giving Vetrimycin™ 200 in conjunction with penicillin.
Reports of adverse reactions associated with oxytetracycline administration include injection site swelling, restlessness, ataxia, trembling, swelling of eyelids, ears, muzzle, anus and vulva (or scrotum and sheath in males), respiratory abnormalities (labored breathing), frothing at the mouth, collapse and possibly death. Some of these reactions may be attributed to anaphylaxis (an allergic reaction) or to cardiovascular collapse of unknown cause.
The use of antibiotics in the management of diseases is based on an accurate diagnosis and an adequate course of treatment. When properly used in the treatment of diseases caused by oxytetracycline-susceptible organisms, most animals that have been treated with Vetrimycin™ 200 show a noticeable improvement within 24-48 hours. It is recommended that the diagnosis and treatment of animal diseases be carried out by a veterinarian. Since many diseases look alike but require different types of treatment, the use of professional veterinary and laboratory services can reduce treatment time, costs, and needless losses. Good housing, sanitation, and nutrition are important in the maintenance of healthy animals, and are essential in the treatment of diseased animals.
Vetrimycin™ 200 is intended for use in the treatment of the following diseases in beef cattle; dairy cattle; calves, including preruminating (veal) calves; and swine when due to oxytetracycline-susceptible organisms:
Cattle: Vetrimycin™ 200 is indicated in the treatment of pneumonia and shipping fever complex associated with Pasteurella spp. and Haemophilus spp.; infectious bovine keratoconjuctivitis (pink eye) caused by Moraxella bovis; foot rot and diphtheria caused by Fusobacterium necrophorum; bacterial enteritis (scours) caused by Escherichia coli; wooden tongue caused by Actinobacillus lignieresii; leptospirosis caused by Leptospira pomona; and wound infections and acute metritis caused by strains of staphylococci and streptococci organisms sensitive to oxytetracycline.
Swine: Vetrimycin™ 200 is indicated in the treatment of bacterial enteritis (scours, colibacillosis) caused by Escherichia coli; pneumonia caused by Pasteurella multocida; and leptospirosis caused by Leptospira pomona. In sows, Vetrimycin™ 200 is indicated as an aid in the control of infectious enteritis (baby pig scours, colibacillosis) in suckling pigs caused by Escherichia coli.
Cattle: Vetrimycin™ 200 is to be administered by intramuscular, subcutaneous (SC, under the skin) or intravenous injection to beef cattle; dairy cattle; and calves, including preruminating (veal) calves.
A single dosage of 9 mg of Vetrimycin™ 200 per lb of body weight administered intramuscularly or subcutaneously is recommended in the treatment of the following conditions:
Vetrimycin™ 200 can also be administered by intravenous, subcutaneous, or intramuscular injection at a level of 3-5 mg of oxytetracycline per lb of body weight per day. In the treatment of severe foot rot and advanced cases of other indicated diseases, a dosage level of 5 mg/lb of body weight per day is recommended. Treatment should be continued 24-48 hours following remission of disease signs; however, not to exceed a total of 4 consecutive days. Consult your veterinarian if improvement is not noted within 24-48 hours of the beginning of treatment.
Swine: A single dosage of 9 mg of Vetrimycin™ 200 per lb of body weight administered intramuscularly in the neck region is recommended in the treatment of bacterial pneumonia caused by Pasteurella multocida in swine, where re-treatment is impractical due to husbandry conditions or where repeated restraint is inadvisable.
Vetrimycin™ 200 can also be administered by intramuscular injection at a level of 3-5 mg of oxytetracycline per lb of body weight per day. Treatment should be continued 24-48 hours following remission of disease signs; however, not to exceed a total of 4 consecutive days. Consult your veterinarian if improvement is not noted within 24-48 hours of the beginning of treatment.
For sows, administer once intramuscularly in the neck region 3 mg of oxytetracycline per lb of body weight approximately 8 hours before farrowing or immediately after completion of farrowing.
For swine weighing 25 lb of body weight and under, Vetrimycin™ 200 should be administered undiluted for treatment at 9 mg/lb but should be administered diluted for treatment at 3 or 5 mg/lb.
* To prepare dilutions, add one part of Vetrimycin™ 200 to 3, 5, or 7 parts of sterile water, or 5% dextrose solution as indicated; the diluted product should be used immediately. |
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9 mg/lb Dosage Volume of Undiluted Vetrimycin™ 200 | 3 or 5 mg/lb Dosage Volume of Diluted Vetrimycin™ 200 | |||
Body weight | 9 mg/lb | 3 mg/lb | Dilution* | 5 mg/lb |
5 lb | 0.2 mL | 0.6 mL | 1:7 | 1.0 mL |
10 lb | 0.5 mL | 0.9 mL | 1:5 | 1.5 mL |
25 lb | 1.1 mL | 1.5 mL | 1:3 | 2.5 mL |
Vetrimycin™ 200 is intended for use in the treatment of disease due to oxytetracycline-susceptible organisms in beef cattle; dairy cattle; calves, including preruminating (veal) calves; and swine. A thoroughly cleaned, sterile needle and syringe should be used for each injection (needles and syringes may be sterilized by boiling in water for 15 minutes). In cold weather, Vetrimycin™ 200 should be warmed to room temperature before administration to animals. Before withdrawing the solution from the bottle, disinfect the rubber cap on the bottle with suitable disinfectant, such as 70% alcohol. The injection site should be similarly cleaned with the disinfectant. Needles of 16-18 gauge and 1-1½ inches long are adequate for intramuscular and subcutaneous injections. Needles 2-3 inches are recommended for intravenous use.
Intramuscular injections in swine should be made by directing the needle of suitable gauge and length into the fleshy part of a thick muscle in the neck region; avoid blood vessels and major nerves. Before injecting the solution, pull back gently on the plunger. If blood appears in the syringe, a blood vessel has been entered; withdraw the needle and select a different site. No more than 10 mL should be injected intramuscularly at any one site in adult beef and dairy cattle, and not more than 5 mL should be injected at any one site in adult swine; rotate injection sites for each succeeding treatment. The volume administered per injection site should be reduced according to age and body size so that 1-2 mL per site is injected in small calves.
Subcutaneous injections in beef cattle, dairy cattle, and calves, including preruminating (veal) calves, should be made by directing the needle of suitable gauge and length through the loose folds of the neck skin in front of the shoulder. Care should be taken to ensure that the tip of the needle has penetrated the skin but is not lodged in muscle. Before injecting the solution, pull back gently on the plunger. If blood appears in the syringe, a blood vessel has been entered; withdraw the needle and select a different site. The solution should be injected slowly in the area between the skin and muscles. No more than 10 mL should be injected subcutaneously at any one site in adult beef and dairy cattle; rotate injection sites for each succeeding treatment. The volume administered per injection site should be reduced according to age and body size so that 1-2 mL per site is injected in small calves.
Vetrimycin™ 200 may be administered intravenously to beef and dairy cattle. As with all highly concentrated materials, Vetrimycin™ 200 should be administered slowly by the intravenous route.
Not for Human Use.
Restricted Drug - California. Use Only as Directed.
MANUFACTURED FOR:
MWI
Boise, ID 83705
(888) 694-8381
www.vetone.net
MADE IN THE UK
MANUFACTURED BY:
Norbrook Laboratories Limited,
Newry, BT35 6PU, Co. Down,
Northern Ireland.
Vetrimycin™ 200 (oxytetracycline) is a sterile, preconstituted solution of the broad-spectrum antibiotic oxytetracycline. Each mL contains 200 mg of oxytetracycline base as oxytetracycline amphoteric, and on a w/v basis, 40.0% 2-pyrrolidone, 5.0% povidone, 1.8% magnesium oxide, 0.2% sodium formaldehyde sulfoxylate (as a preservative), monoethanolamine and/or hydrochloric acid as required to adjust pH.
CAUTION: When administered to cattle, muscle discoloration may necessitate trimming of the injection site(s) and surrounding tissues during the dressing procedure.
Exceeding the highest recommended level of drug per lb of body weight per day, administering more than the recommended number of treatments, and/or exceeding 10 mL intramuscularly or subcutaneously per injection site in adult beef and dairy cattle, and 5 mL intramuscularly per injection site in adult swine, may result in antibiotic residues beyond the withdrawal period.
TAKE TIME
OBSERVE LABEL DIRECTIONS
Lot No.:
Exp. Date:
CATTLE: A single dosage of 9 mg of oxytetracycline per lb of body weight (4.5 mL/100 lb) administered intramuscularly or subcutaneously is recommended in the treatment of the following conditions:
SWINE: A single dose of 9 mg of oxytetracycline per lb of body weight (4.5 mL/100 lb) administered intramuscularly is recommended in the treatment of bacterial pneumonia caused by Pasteurella multocida in swine, where retreatment is impractical due to husbandry conditions or where repeated restraint is inadvisable.
Refer to Package Insert for Complete Directions.
STORAGE: Store at 59° to 86°F (15° to 30°C). Keep from freezing.
Not for Human Use. For Animal Use Only.
Restricted Drug - California. Use Only as Directed.
Manufactured for: MWI
Boise, ID 83705
(888) 694-8381
www.vetone.net
Made in the UK.
Manufactured by:
Norbrook Laboratories Limited,
Newry, BT35 6PU, Co. Down,
Northern Ireland.
NDC 13985-035-05 500 mL
VETone®
Vetrimycin™ 200
(oxytetracycline) 200 mg/mL
Antibiotic
Injection
Each mL contains 200 mg of oxytetracycline
base as amphoteric oxytetracycline.
For the treatment of disease in beef cattle;
dairy cattle; calves, including
preruminating (veal) calves; and swine.
ANADA 200-306, Approved by FDA
V1 504020 Net Contents: 500 mL
NDC 13985-035-05 500 mL
VETone®
Vetrimycin™ 200
(oxytetracycline) 200 mg/mL
Antibiotic
Injection
Each mL contains 200 mg of oxytetracycline
base as amphoteric oxytetracycline.
For the treatment of disease in beef
cattle; dairy cattle; calves, including
preruminating (veal) calves; and swine.
ANADA 200-306, Approved by FDA
V1 504020 Net Contents: 500 mL
VETRIMYCIN 200
oxytetracycline injection, solution |
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Labeler - MWI Veterinary Supply Co (019926120) |
Registrant - Norbrook Laboratories Limited (214580029) |
Establishment | |||
Name | Address | ID/FEI | Business Operations |
---|---|---|---|
Norbrook Laboratories Limited | 232880554 | API MANUFACTURE, MANUFACTURE, ANALYSIS |