Calcium Chloride

CALCIUM CHLORIDE
INJECTION, USP, 10%

13.6 mEq (1 g) per 10 mL
100 mg (1.36 mEq)/ mL
Osmolarity approximately 2050 mOsmol/L

Calcium Chloride Injection, USP, 10%, is a sterile aqueous solution containing, in each mL, 100 mg (1.36 mEq) calcium chloride. The pH of the solution may have been adjusted with hydrochloric acid and / or calcium hydroxide, when necessary. The air above the liquid in the individual containers has been displaced by flushing with nitrogen during the filling operation. The preparation contains no antimicrobial preservatives and is intended as a single-dose vial; once the unit is assembled and used, any remaining portion of the solution must be discarded with the entire unit.

Calcium Chloride, USP, contains two molecules of water of hydration and is chemically designated as CaCl ₂ • 2H ₂0.

Calcium is the fifth most abundant element in the body, the major fraction of which is found in the bony structure. Calcium plays important physiological roles; it is essential for the functional integrity of the nervous and muscular systems; it is necessary for normal cardiac function; and it is one of the factors involved in the mechanism of blood coagulation.

Calcium Chloride Injection, USP, 10% is indicated:

In the treatment of hypocalcemia in conditions requiring a prompt increase in plasma calcium levels (e.g., neonatal tetany and tetany due to parathyroid deficiency, vitamin D deficiency and alkalosis) and for prevention of hypocalcemia during exchange transfusions.

As adjunctive therapy in the management of acute symptoms in lead colic.

In the treatment of magnesium intoxication due to overdosage of magnesium sulfate.

In severe hyperkalemia, to combat deleterious effects on electrocardiographic (ECG) function, pending correction of the potassium level in the extracellular fluid.

In cardiac resuscitation, particularly after open heart surgery, when epinephrine fails to improve weak or ineffective myocardial contractions.

Calcium chloride is contraindicated for cardiac resuscitation in the presence of ventricular fibrillation.

Calcium chloride should be injected into a large vein very slowly, as it may cause peripheral vasodilatation and a cutaneous burning sensation. A moderate fall in blood pressure due to vasodilatation may attend the injection. Since calcium chloride is an acidifying salt, it is usually undesirable in the treatment of hypocalcemia or renal insufficiency.

CALCIUM CHLORIDE INJECTION, USP, 10%

In unit-use packages containing a Luer-Jet™ Luer-Lock Prefilled Syringe.

Stock No. 3304      NDC 76329-3304-1      10 mL

Ten cartons per package.

Syringe Assembly Directions:
USE ASEPTIC TECHNIQUE
Do not assemble until ready to use.

Instructions

*CAUTION: IMPROPER ENGAGING MAY CAUSE GLASS BREAKAGE AND SUBSEQUENT INJURY.

Store at controlled room temperature 15° to 30°C (59° to 86°F).

Rx Only

INTERNATIONAL MEDICATION SYSTEMS, LIMITEDSo. El Monte, CA 91733, U.S.A.                                         Rev. 2-13
An Amphastar Pharmaceuticals Company

© INTERNATIONAL MEDICATION SYSTEMS, LIMITED 2013

Osmolarity approx. 2050 mOsmol per liter (calc.)

FOR SLOW INTRAVENOUS USE ONLY

SEE INSERT / SINGLE DOSE

NO PRESERVATIVE ADDED

IMS, LIMITED

Rx Only

So. El Monte, CA 91733, U.S.A.

7633040B 8-11

10 mL      1 g (13.6 mEq)       100 mg / mL

CALCIUM CHLORIDE INJ., USP, 10%

Approx. mL  0   1   2   3   4   5   6   7   8   9

Label

Luer-Lock Prefilled Syringe

Rx only

NDC 76329-3304-1

STOCK NO. 3304

CALCIUM CHLORIDE INJ. USP, 10%

1.36 mEq/ mL (100 mg/ mL)

13.6 mEq (1 g) per 10 mL

One 10 mL Single Dose Prefilled Syringe

Single use, do not reuse or resterilize.

FOR SLOW INTRAVENOUS USE

LUER-JET ^TM LUER-LOCK PREFILLED SYRINGE

Carton

NDC 71872-7044-1

1 - Prefilled Syringe

Calcium Chloride Inj. USP, 10%

Rx Only

calclabel