FDA.reportPublic FDA data

Head and Shoulders 2in1 Men Advanced Series Full and Thick

Manufacturer
The Procter & Gamble Manufacturing Company
Effective date
2025-01-29
Label type
HUMAN OTC DRUG LABEL
Version
7
Source
full-release
Hydrated at
2026-06-01 00:53:56

Label at a glance#

ProductHead and Shoulders 2in1 Men Advanced Series Full and Thick
Active ingredientPYRITHIONE ZINC
Label structure10 sections

Indications and uses

helps prevent recurrence of flaking and itching associated with dandruff.

Dosage and administration

for best results use at least twice a week or as directed by a doctor. for maximum dandruff control, use every time you shampoo. shake before use. wet hair, massage onto scalp, rinse, repeat if desired.

Label contents#

Full prescribing information#

SPL UNCLASSIFIED SECTION

Drug Facts

Active ingredient

OTC - ACTIVE INGREDIENT SECTION

Pyrithione zinc 1%

Purpose

OTC - PURPOSE SECTION

Anti-dandruff

Uses

INDICATIONS & USAGE SECTION

helps prevent recurrence of flaking and itching associated with dandruff.

Warnings

WARNINGS SECTION

SPL UNCLASSIFIED SECTION

For external use only.

OTC - WHEN USING SECTION

When using this product

  • avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water.

OTC - STOP USE SECTION

Stop use and ask a doctor if

  • condition worsens or does not improve after regular use of this product as directed.

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

Keep this and all drugs out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Directions

DOSAGE & ADMINISTRATION SECTION

  • for best results use at least twice a week or as directed by a doctor.
  • for maximum dandruff control, use every time you shampoo.
  • shake before use.
  • wet hair, massage onto scalp, rinse, repeat if desired.

Inactive ingredients

INACTIVE INGREDIENT SECTION

Water, sodium lauryl sulfate, sodium laureth sulfate, glycol distearate, sodium chloride, zinc carbonate, dimethicone, cocamidopropyl betaine, sodium xylenesulfonate, fragrance, sodium benzoate, menthol, guar hydroxypropyltrimonium chloride, magnesium carbonate hydroxide, caffeine, methylchloroisothiazolinone, methylisothiazolinone, blue 1, red 33

Questions (or comments)?

OTC - QUESTIONS SECTION

1-800-723-9569

SPL UNCLASSIFIED SECTION

Dist. by PROCTER & GAMBLE,
CINCINNATI, OH 45202

PRINCIPAL DISPLAY PANEL - 370 mL Bottle Label

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

head &
shoulders ®

pyrithione zinc dandruff shampoo

2in1

MEN

ADVANCED SERIES™

FULL & THICK

CLEANS TO RESTORE FULLNESS

TO THINNING HAIR

INFUSED WITH CAFFEINE

FLAKE FREE.*

UP TO 100%

GUARANTEED^

12.5 FL OZ (370 mL)

HSHS

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYSPL version
1043244head & shoulders 1 % Medicated ShampooPSN7
209884zinc pyrithione 1 % Medicated ShampooPSN7
1043244zinc pyrithione 10 MG/ML Medicated Shampoo [Head & Shoulders]SBD7
209884zinc pyrithione 10 MG/ML Medicated ShampooSCD7
1043244Head & Shoulders 1 % Medicated ShampooSY7
1043244Head & Shoulders 10 MG/ML Medicated ShampooSY7
209884zinc pyrithione 1 % Medicated ConditionerSY7
209884zinc pyrithione 1 % Medicated ShampooSY7

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
7dea7767-9f52-b60a-5435-33cb9cc28baeProduct name420250124
6338270f-96cb-0ecb-6fbb-0a9bc78001f4Product name720250116
0ca83774-3f79-b837-5d6f-c210102f3bc8Product name620250114
41b814f3-0166-1c53-c9ef-a0794c7daf9dProduct name320221110
a590be26-846c-8659-a5a1-fb25907965dcProduct name220221110
2dc76302-91c0-4c35-ad78-99adfb049c4bProduct name120200603
e6065d4b-5ae1-476f-a40e-f2851cbb5d2bProduct name220180221
f212291f-05fe-9603-fc7e-bd73e38ce1e6Product name220161129
182f9ab4-4ab5-c449-200f-87ce2ce8e550Product name220151105
332e86c3-7875-ca6e-f934-2206d2b31996Product name120140508
56625fcc-aa34-9d30-d0e9-1c1beb37ea21Product name120140508
7dfac40f-a405-cd2e-7c06-3059ec0e1092Product name120140508
96c2be53-8e44-452d-56a2-d255b2f1af2dProduct name120140508
bf8bd5f7-495f-4022-2780-7ded7ea7ea44Product name120140508
d223c173-c39b-d764-47d4-d671d3088815Product name120140508
e01133ad-4dcd-c7f3-454b-2ff569ee160aProduct name120140508

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDCEffectiveActionDocumentIndexing SPLRelated label
69423-329-382022-12-16C16284748780-19d75b9d0-c3a3-f424-e053-dadaa90a57ceHead and Shoulders ® 2in1 Men Advanced Series Full & Thick Shampoo
69423-329-652022-12-16C16284748780-19d75b9d0-c3a3-f424-e053-dadaa90a57ceHead and Shoulders ® 2in1 Men Advanced Series Full & Thick Shampoo
69423-329-932022-12-16C16284748780-19d75b9d0-c3a3-f424-e053-dadaa90a57ceHead and Shoulders ® 2in1 Men Advanced Series Full & Thick Shampoo
69423-329-382022-01-28C16284748780-19d75b9d0-c3a3-f424-e053-dadaa90a57ceHead and Shoulders ® 2in1 Men Advanced Series Full & Thick Shampoo
69423-329-652022-01-28C16284748780-19d75b9d0-c3a3-f424-e053-dadaa90a57ceHead and Shoulders ® 2in1 Men Advanced Series Full & Thick Shampoo
69423-329-932022-01-28C16284748780-19d75b9d0-c3a3-f424-e053-dadaa90a57ceHead and Shoulders ® 2in1 Men Advanced Series Full & Thick Shampoo
69423-329-382020-02-06C16284748780-19d75b9d0-c3a3-f424-e053-dadaa90a57ceHead and Shoulders ® 2in1 Men Advanced Series Full & Thick Shampoo
69423-329-652020-02-06C16284748780-19d75b9d0-c3a3-f424-e053-dadaa90a57ceHead and Shoulders ® 2in1 Men Advanced Series Full & Thick Shampoo
69423-329-932020-02-06C16284748780-19d75b9d0-c3a3-f424-e053-dadaa90a57ceHead and Shoulders ® 2in1 Men Advanced Series Full & Thick Shampoo
69423-329-382020-01-31C16284748780-19d75b9d0-c3a3-f424-e053-dadaa90a57ceHead and Shoulders ® 2in1 Men Advanced Series Full & Thick Shampoo
69423-329-652020-01-31C16284748780-19d75b9d0-c3a3-f424-e053-dadaa90a57ceHead and Shoulders ® 2in1 Men Advanced Series Full & Thick Shampoo
69423-329-932020-01-31C16284748780-19d75b9d0-c3a3-f424-e053-dadaa90a57ceHead and Shoulders ® 2in1 Men Advanced Series Full & Thick Shampoo

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
69423-329-01Head and Shoulders 2in1 Men Advanced Series Full and Thick2 in 1 CELLO PACKLOTION/SHAMPOO27
69423-329-01Head and Shoulders 2in1 Men Advanced Series Full and Thick930 mL in 1 BOTTLE, PUMPLOTION/SHAMPOO9307
69423-329-37Head and Shoulders 2in1 Men Advanced Series Full and Thick370 mL in 1 BOTTLE, PLASTICLOTION/SHAMPOO3707
69423-329-38Head and Shoulders 2in1 Men Advanced Series Full and Thick380 mL in 1 BOTTLE, PLASTICLOTION/SHAMPOO3807
69423-329-61Head and Shoulders 2in1 Men Advanced Series Full and Thick613 mL in 1 BOTTLE, PLASTICLOTION/SHAMPOO6137
69423-329-65Head and Shoulders 2in1 Men Advanced Series Full and Thick650 mL in 1 BOTTLE, PLASTICLOTION/SHAMPOO6507
69423-329-83Head and Shoulders 2in1 Men Advanced Series Full and Thick835 mL in 1 BOTTLE, PUMPLOTION/SHAMPOO8357
69423-329-93Head and Shoulders 2in1 Men Advanced Series Full and Thick930 mL in 1 BOTTLE, PUMPLOTION/SHAMPOO9307

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
69423-329HEAD AND SHOULDERS 2IN1 MEN ADVANCED SERIES FULL AND THICK (PYRITHIONE ZINC) LOTION/SHAMPOO [THE PROCTER & GAMBLE MANUFACTURING COMPANY]7Current NDC, Legacy NDC, 8 package rows20250130_7d3f0664-a9e7-6b63-e053-2991aa0a4b0a.zip

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 20 matching rows.

NDC Codes#

Product NDC, Package NDC table
Product NDCPackage NDC
69423-32969423-329-38, 69423-329-65, 69423-329-93, 69423-329-37, 69423-329-61, 69423-329-83, 69423-329-01

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 19 matching rows.

Name, UNII, Kind table
NameUNIIKind
SODIUM LAURYL SULFATE368GB5141JIACT
WATER059QF0KO0RIACT
SODIUM LAURETH-3 SULFATEBPV390UAP0IACT
GLYCOL DISTEARATE13W7MDN21WIACT
ZINC CARBONATEEQR32Y7H0MIACT
SODIUM CHLORIDE451W47IQ8XIACT
SODIUM XYLENESULFONATEG4LZF950URIACT
COCAMIDOPROPYL BETAINE5OCF3O11KXIACT
DIMETHICONE92RU3N3Y1OIACT
SODIUM BENZOATEOJ245FE5EUIACT
MAGNESIUM CARBONATE HYDROXIDEYQO029V1L4IACT
METHYLCHLOROISOTHIAZOLINONEDEL7T5QRPNIACT
METHYLISOTHIAZOLINONE229D0E1QFAIACT
FD&C BLUE NO. 1H3R47K3TBDIACT
D&C RED NO. 339DBA0SBB0LIACT
PYRITHIONE ZINCR953O2RHZ5ACTIB
MENTHOLL7T10EIP3AIACT
GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE (1.7 SUBSTITUENTS PER SACCHARIDE)B16G315W7AIACT
CAFFEINE3G6A5W338EIACT

Source Document#

Source XML

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Head and Shoulders 2in1 Men Advanced Series Full and ThickPYRITHIONE ZINCThe Procter & Gamble Manufacturing Company7d3f0664-a9e7-6b63-e053-2991aa0a4b0a2025-01-29WarningsExact identifier
ndc (package): 69423-329-83
ndc (package): 69423-329-93
ndc (package): 69423-329-37
ndc (package): 69423-329-38
ndc (package): 69423-329-61
ndc (package): 69423-329-01
ndc (package): 69423-329-65
ndc (product): 69423-329
ndc11 (package): 69423032937
ndc11 (package): 69423032983
ndc11 (package): 69423032961
ndc11 (package): 69423032965
ndc11 (package): 69423032901
ndc11 (package): 69423032938
ndc11 (package): 69423032993
spl id: 2cdaa7a5-cca6-20a9-e063-6294a90a1008
spl set id: 7d3f0664-a9e7-6b63-e053-2991aa0a4b0a

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.