Drug Label
- Manufacturer
- MARS FISHCARE NORTH AMERICA, INC. | Alivira Animal Health Limited
- Effective date
- 2026-04-21
- Label type
- OTC ANIMAL DRUG LABEL
- Version
- 6
- Source
- full-release
- Hydrated at
- 2026-06-01 02:46:52
Label at a glance#
Contacts and useful links#
Label contents#
Full prescribing information#
OTC - ACTIVE INGREDIENT SECTION
Active Ingredients: 500 mg Metronidazole and 150 mg Praziquantel per teaspoon.
DOSAGE & ADMINISTRATION SECTION
Directions for Use:
For best results, remove activated carbon or filter cartridge from filter and continue aeration.
For each 20 gallons (75 L) of water add 1 scoop (1 tsp.).
For larger systems, for each 240 gallons (908 L) of water add 12 scoops (4 Tbsp.). or for each 960 gallons (3,634 L) of water add one cup.
Repeat dose after 48 hours.
Wait another 48 hours then change 25% of the aquarium water and add API BIO CHEM ZORB, fresh activated carbon or replace filter cartridge.
Will not discolor water.
Safe for use with live plants
WARNINGS AND PRECAUTIONS SECTION
KEEP OUT OF THE REACH OF CHILDREN.
For aquarium use only.
Not for human consumption or for the treatment of fish intended for human consumption.
Avoid contact with skin and eyes.
May cause irritation.
! WARNING:
This product can expose you to chemicals including Metronidazole, which is known to the State of California to cause cancer.
For more information go to
www.P65Warnings.ca.gov.
INDICATIONS & USAGE SECTION
Diagnostic Chart
Gill and Skin Flukes:
Very common fish parasites. Can be found on the gills, scales or skin. Not visible without the aid of magnification. Symptoms may include: darkening of skin, clamped fins, excess mucous. Fish may also swim erratically or become emaciated.
Hole-in-the-Head Disease:
Symptoms include pitting and erosion of skin and muscle tissue around the face and side of body. Many infected fish exhibit poor appetite, weight loss and nervousness.
Wasting Disease:
Fish parasites transmitted fromn fish to fish cause emaciation, anemia and lethargy.Tissue damage leading to subsequent ulceration of the gastrointestinal tract. Excess mucus and white stringy feces are often produced as a result of parasitic invasion.
Swollen Abdomen:
Fish infected with tapeworms (cestodes), often have an extended or swollen abdomen. Internal area of attachment results in damaged tissue. Fish normally show signs of reduction ingrowth and general malaise.
Treatment Tips
Quarantine aquarium. Remove any dead fish immediately. Do not remove or add any live fish to the infected aquarium. Parasitic infections are highly contagious and can spread to other aquariums by nets, algae scrapers and wet hands.
To speed up the life cycle of parasites and shorten treatment period, raise water temperature to 82 F (28 C).
To aid osmoreregulation and ease stress of infected fish, add 1 tablespoon of API AQUARIUM SALT for each 5 gallons (19 L) of aquarium water, or 1 -1/4 cup for each 100 gallons (378 L).
This medication may be used in combination with API antibacterial medications, including API MELAFIX, to help prevent scondary bacterial infection.
PACKAGE LABEL.PRINCIPAL DISPLAY PANEL
API
GENERAL CURE
TREATS PARASITIC FISH DISEASE
Eliminates a wide variety of parasites
Fastacting
Gill and Skin Flukes
Hole-in-the-Head
Swollen Abdomen
Wasting Disease
GUIDE
Fish Problem
Solving
850 g
Treats 3,270 U.S. gallons (12,375 L) of fresh or salt water
DailyMed Pharmacologic Classes#
| Class | Version | Type | Effective |
|---|---|---|---|
| METRONIDAZOLE Pharmacologic Class Indexing | 2 | Indexing - Pharmacologic Class | 20180813 |
| PRAZIQUANTEL Pharmacologic Class Indexing | 3 | Indexing - Pharmacologic Class | 20190712 |
DailyMed Product Concepts#
| Product concept | Relation | Version | Effective |
|---|---|---|---|
| 8ffb9b1d-3ed7-ba2e-677e-47d4d134fd55 | Product name | 5 | 20251024 |
| 7f6d14e0-4366-41bc-a4a9-b74c79a20e17 | Product name | 1 | 20250623 |
| e6d321b0-0e5e-7da6-f043-92b6a91f00a1 | Product name | 5 | 20250515 |
| e1aac33b-94ae-4ee9-905b-299f7263853b | Product name | 3 | 20250124 |
| 16642716-d28a-4f90-8dcb-3921cd8c8109 | Product name | 4 | 20240516 |
| 0be8e4ae-4d57-49f3-b3a9-e4728b4e8d15 | Product name | 1 | 20240313 |
| dea2eded-d1e7-46bb-9a3d-f8dc20de6277 | Product name | 1 | 20190408 |
| a5070875-62bb-61e1-fd46-8f7054197a40 | Product name | 8 | 20180215 |
| 8cabd598-669e-43ab-9753-4aec00a484cb | Product name | 1 | 20180125 |
| 0add4de9-d152-3375-3390-1123dddc5e3d | Product name | 1 | 20140508 |
| 33ca0fcc-1011-92dc-50a9-a383683eed1e | Product name | 1 | 20140508 |
| 53f39d9f-cd3f-04e1-c668-d4580719d57d | Product name | 1 | 20140508 |
| a804000f-b74f-0b5d-d17b-aa767c286ddb | Product name | 1 | 20140508 |
| a91ea265-6e02-c08f-93c8-686d54180529 | Product name | 1 | 20140508 |
DailyMed Package Descriptions#
| Package NDC | Product | Description | Form | Quantity | Strength | SPL version |
|---|---|---|---|---|---|---|
| 17163-016-17 | API GENERAL CURE | 850 g in 1 JAR | POWDER | 850 | 6 |
Products#
Every source-derived product name is available through these pages.
- API GENERAL CURE
- Metronidazole Praziquantel
- METRONIDAZOLE
- PRAZIQUANTEL
NDC Codes#
| Product NDC | Package NDC |
|---|---|
| 17163-016 | 17163-016-17 |
Ingredients#
Every source-derived ingredient row is available through these pages.
| Name | UNII | Kind |
|---|---|---|
| METRONIDAZOLE | 140QMO216E | ACTIB |
| PRAZIQUANTEL | 6490C9U457 | ACTIB |
Source Document#
openFDA label cross-check#
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| Metronidazole | METRONIDAZOLE | NuCare Pharmaceuticals, Inc. | 4040db14-750f-6d20-e054-00144ff8d46c | 2026-08-26 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | Major Pharmaceuticals | 71f5ce2f-17f8-45fc-b27d-2bf982591ab3 | 2026-08-21 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | REMEDYREPACK INC. | 5cc3fd98-d579-432e-a4b5-b6d5586991a6 | 2026-08-05 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | REMEDYREPACK INC. | dc28753c-95ec-4b41-ad77-c4a66698d9db | 2026-08-04 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| metronidazole | METRONIDAZOLE | REMEDYREPACK INC. | b49a8ad0-2cf9-4386-8bf5-1b1df87b0022 | 2026-08-03 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| metronidazole | METRONIDAZOLE | REMEDYREPACK INC. | d5784eeb-6b99-4e8a-847b-b0d1090ed48a | 2026-07-28 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | REMEDYREPACK INC. | 2f7d84d4-1085-4243-be88-442eecb85205 | 2026-07-22 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| Vagizole | METRONIDAZOLE | iNutrition LLC | fd5e884b-cf07-493b-bb93-039bbb0c4784 | 2026-07-22 | Warnings, Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | Bryant Ranch Prepack | 5cf3cc1f-601e-4997-bfb2-a573c31c8189 | 2026-07-15 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | Sun Pharmaceutical Industries, Inc. | 4a233572-2471-4e99-a45e-2de978abcf16 | 2026-07-15 | Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | Sun Pharmaceutical Industries, Inc. | 5a504f74-bccd-433a-bd5b-6822f98c34df | 2026-07-15 | Warnings, Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | Sun Pharmaceutical Industries, Inc. | 5842a554-58d1-4ee4-99aa-1e6029a69be2 | 2026-07-15 | Warnings, Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | Bryant Ranch Prepack | 4748ba37-9d66-497d-aa9f-ca2d541c5f41 | 2026-07-15 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | Preferred Pharmaceuticals Inc. | 59e53582-244a-4e9d-b18e-75dddc6a5052 | 2026-07-08 | Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | REMEDYREPACK INC. | cfeab9e3-58b9-4890-9185-11b62904e2af | 2026-07-07 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | Preferred Pharmaceuticals Inc. | cbee69e8-029c-49d2-89cd-f504b8e0ac28 | 2026-07-07 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | Preferred Pharmaceuticals Inc. | 3e0a14f1-961b-4722-bfea-aafcc5d7706c | 2026-07-07 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | REMEDYREPACK INC. | 53918705-d2fe-4c6b-9501-a619a8ad3991 | 2026-07-03 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | Kanchan Healthcare Inc | 8836334e-6db4-44be-bc9e-099b26322cf4 | 2026-07-01 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| metronidazole | METRONIDAZOLE | Bryant Ranch Prepack | 99886f54-4ebe-4a2d-b779-bcfbb0634db1 | 2026-06-30 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
Reported adverse events (FAERS/openFDA)#
Adverse event summaries are temporarily unavailable. Other product information remains available.
