Severe Anefrin Nasal Spray No Drip MAXIMUM STRENGTH 12 Hour Menthol

Severe Anefrin by

Drug Labeling and Warnings

Severe Anefrin by is a Otc medication manufactured, distributed, or labeled by WALGREENS. Drug facts, warnings, and ingredients follow.

Drug Details [pdf]

SEVERE ANEFRIN- oxymetazoline hydrochloride liquid 
WALGREENS

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Severe Anefrin Nasal Spray
No Drip
MAXIMUM STRENGTH
12 Hour
Menthol

ACTIVE INGREDIENT

Oxymetazoline hydrochloride 0.05%

Warnings Ask a doctor before use if you have

heart disease high blood pressure thyroid disease diabetes trouble urinating due to an enlarged prostate gland

When using this product do not use more than directed

do not use for more than 3 days. Use only as directed. Frequent or prolonged use may cause nasla congestion to recur or worsen. temporary discomfort such as burning, stinging, sneezing or an increase in nasla discharge may occur use of this container by more than one person may spread infection. Stop use and ask a doctor if symptoms persist

If Pregnant or breast-feeding,

ask a health professional before use.

Keep out of reach of children.

If swallowed, get medical help or contact a Poison Control Center right away.

Directions

adults and children 6 to under 12 years of age (with adult supervision): 2 or 3 sprays in each nostril not more often than every 10 to 12 hours. Do not exceed 2 doses in any 24-hour period. children under 6 years of age: ask a doctor

To Use:

Shake well before use. Hold white tabs, press grooved area of cap firmly and turn counterclockwise. Before using the firsst time, prime metered pump by depressing pump firmly several times. To spray, hold bottle with thumn at base and nozzle between first and second fingers. Without tilting head, insert nozzle into nostril. Fully depress rim with a firm, even stroke and sniff deeply. Wipe nozzle clean after use. Secure cap after use.

Questions or comments? 1-800-925-4733.

DISTRIBUTED BY: WALGREENS CO.
200 WILMOT RD., DEERFIELD, IL 60015

100% SATISFACTION GUARANTEED

walgreens.com ©2020 Walgreen Co.

Inactive Ingredients

Benzalkonium Chloride Solution, Camphor, CArboxymethyl Cellulose Sodium, Cellulose Gum, Disodium EDTA, Disodium Phosphate, Eucalyptol, Glycerin, Menthol, Microcrystalline Cellulose, PEG-6, Povidone, Propylene Glycol, Purified Water, Sodium Phosphate Monobasic

Uses

temporarily relives nasal congestions due to:

common cold hay fever upper respiratory allergies

temporarily relieves sinus congestgions and pressure

shrinks swollen nasal membranes so you can breath more freely

PURPOSE

Nasal Decongestant

Severe Anefrin Nasal Spray

NO DRIP

MAXIMUM STRENGTH

12 HOUR

+ MENTHOL

SEVERE ANEFRIN 
oxymetazoline hydrochloride liquid

Product Information
Product Type	HUMAN OTC DRUG	Item Code (Source)	NDC: 0363-2021
Route of Administration	NASAL

Active Ingredient/Active Moiety
Ingredient Name	Basis of Strength	Strength
OXYMETAZOLINE HYDROCHLORIDE (UNII: K89MJ0S5VY) (OXYMETAZOLINE - UNII:8VLN5B44ZY)	OXYMETAZOLINE HYDROCHLORIDE	0.05 g  in 15 mL

Inactive Ingredients
Ingredient Name	Strength
EDETATE DISODIUM (UNII: 7FLD91C86K)
EDETATE DISODIUM ANHYDROUS (UNII: 8NLQ36F6MM)
EUCALYPTOL (UNII: RV6J6604TK)
GLYCERIN (UNII: PDC6A3C0OX)
MENTHOL, (+)- (UNII: C6B1OE8P3W)
PEG-6 STEARATE (UNII: 8LQC57C6B0)
CAMPHOR, (-)- (UNII: 213N3S8275)
POVIDONE K30 (UNII: U725QWY32X)
PROPYLENE GLYCOL (UNII: 6DC9Q167V3)
SODIUM PHOSPHATE, DIBASIC, MONOHYDRATE (UNII: BWZ7K44R51)
CARBOXYMETHYLCELLULOSE SODIUM, UNSPECIFIED (UNII: K679OBS311)
BENZALKONIUM CHLORIDE (UNII: F5UM2KM3W7)

Packaging
#	Item Code	Package Description	Marketing Start Date	Marketing End Date
1	NDC: 0363-2021-15	1 in 1 BOTTLE, SPRAY	02/08/2021	12/31/2023
1		15 mL in 1 BOTTLE, SPRAY; Type 0: Not a Combination Product

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
OTC Monograph Drug	M012	02/08/2021	12/31/2023

Labeler - WALGREENS (008965063)

Revised: 12/2025

Document Id: 471ae14b-db44-d4d2-e063-6294a90af58e

34390-5

Set id: b637e03a-dc2b-92a3-e053-2995a90a9a6b

Version: 6

Effective Time: 20251229