DOUXO S3 by Ceva Sante Animale

DOUXO S3 by

Drug Labeling and Warnings

DOUXO S3 by is a Animal medication manufactured, distributed, or labeled by Ceva Sante Animale. Drug facts, warnings, and ingredients follow.

Drug Details [pdf]

DOUXO S3 CARE- ophytrium shampoo 
Ceva Sante Animale

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

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DOUXO S3™ Care

OPHYTRIUM 0.25%

Soap, sulfate, paraben, phthalate, colorant and nanoparticle FREE

High tolerance formula. Hypoallergenic fragrance, adjusted pH. Formulated and tested by veterinary dermatology experts.

ACTIVE INGREDIENT: Ophytrium 0.25%

INACTIVE INGREDIENTS: Water, cocamidopropyl hydroxysultaine, sodium methyl lauroyl isethionate, sodium methyl cocoyl taurate, disodium laureth sulfosuccinate, sodium cocoamphoacetate, glycol distearate, panthenol, pentavitin® (saccharide isomerate), niacinamide (Vit. PP), jojoba esters, coco+vanilla hypoallergenic fragrance, phenoxyethanol, guar gum, acrylates/C10-30 alkyl acrylate, sodium benzoate, disodium EDTA, citric acid, sodium hydroxide.

PROPERTIES: Ophytrium is a purified, natural ingredient from the S3 - Safe Skincare Selection. Ophytrium has been carefully selected for its high tolerance and simultaneous threefold action on the skin’s ecosystem:
Helps support the skin's physical barrier for supple, hydrated skin Helps support the microbial flora for healthy skin Helps soothe irritated skin

INDICATIONS: For use on dogs or cats to clean and hydrate the skin. Detangles the fur and leaves the coat soft and shiny. Ultra-gentle and protecting for regular use, suitable for all fur types.

DIRECTIONS: Use one pump for every 4 lbs. Double the dosage for long and/or thick fur. Wet with cool water from the neck down. Apply, massage and leave-on for several minutes before rinsing. Repeat if necessary.

CAUTIONS: For external use on dogs or cats only. Avoid contact with eyes. If eye contact occurs, rinse thoroughly and consult your veterinarian. If skin irritation occurs or increases, discontinue use and consult with your veterinarian. Keep out of reach of children.

Store at room temperature.

“How to use” video www.douxo.com

Manufactured for Ceva Animal Health, LLC, Lenexa, KS 66215, 800-999-0297
Pentavitin® is a registered trademark of DSMP Assets B.V.
All other trademarks are owned by Ceva Santé Animale S.A. or its affiliates.

PRINCIPAL DISPLAY PANEL - 200 mL Bottle

DOUXO S3™

CARE

OPHYTRIUM 0.25%

ultra-gentle protecting

FOR REGULAR USE

shampoo

For use on dogs or cats

6.7 fl oz (200 mL)

200 mL Bottle Label

PRINCIPAL DISPLAY PANEL - 500 mL Bottle

DOUXO S3™

CARE

OPHYTRIUM 0.25%

ultra-gentle protecting

FOR REGULAR USE

shampoo

For use on dogs or cats

16.9 fl oz (500 mL)

500 mL Bottle Label

DOUXO S3  CARE
ophytrium shampoo
Product Information
Product TypeOTC ANIMAL DRUGItem Code (Source)NDC: 13744-152
Route of AdministrationTOPICAL
Active Ingredient/Active Moiety
Ingredient NameBasis of StrengthStrength
OPHIOPOGON JAPONICUS ROOT (UNII: 90PS6JV9GZ) (OPHIOPOGON JAPONICUS ROOT - UNII:90PS6JV9GZ) OPHIOPOGON JAPONICUS ROOT2.5 mg  in 1 mL
Inactive Ingredients
Ingredient NameStrength
GLYCOL DISTEARATE (UNII: 13W7MDN21W)  
SACCHARIDE ISOMERATE (UNII: W8K377W98I)  
NIACINAMIDE (UNII: 25X51I8RD4)  
POTASSIUM HYDROLYZED JOJOBA ESTERS (UNII: CH428W5O62)  
PHENOXYETHANOL (UNII: HIE492ZZ3T)  
GUAR GUM (UNII: E89I1637KE)  
CARBOMER INTERPOLYMER TYPE A (ALLYL SUCROSE CROSSLINKED) (UNII: 59TL3WG5CO)  
SODIUM BENZOATE (UNII: OJ245FE5EU)  
EDETATE DISODIUM (UNII: 7FLD91C86K)  
CITRIC ACID MONOHYDRATE (UNII: 2968PHW8QP)  
SODIUM HYDROXIDE (UNII: 55X04QC32I)  
Packaging
#Item CodePackage DescriptionMarketing Start DateMarketing End Date
1NDC: 13744-152-01200 mL in 1 BOTTLE, PLASTIC
2NDC: 13744-152-02500 mL in 1 BOTTLE, PLASTIC
Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
unapproved drug other11/25/202001/01/2026
Labeler - Ceva Sante Animale (261126049)
Registrant - Ceva Sante Animale (261126049)

Revised: 1/2026
 

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