OXYBUTYNIN Pharmacologic Class Indexing

Class set ID
a4cd5d5c-5cb0-434c-ba16-5ceb0c9176b0
Version
2
Effective date
20180813
Type
Indexing - Pharmacologic Class

Mapped DailyMed Labels#

Label, Manufacturer, Effective table
LabelManufacturerEffectiveSPL version
OXYBUTYNIN CHLORIDE TABLETS, USPStrides Pharma Science Limited202606016
Oxybutynin Chloride Tablet, USPHeritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. | Heritage Pharma Labs Inc. d/b/a Avet Pharmaceuticals Labs Inc.202605202
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE extended-release tablets for oral use Initial U.S. Approval: 1975Bryant Ranch Prepack202605195
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE extended-release tablets, for oral use Initial U.S. Approval: 1975Bryant Ranch Prepack20260514102
OXYBUTYNIN CHLORIDE TABLETS, USPRISING PHARMA HOLDINGS, INC. | Piramal Pharma Limited202604271
Oxybutynin Chloride Tablets, USP 8489901/0425 Rx onlyAmerican Health Packaging202604162
Oxybutynin Chloride Tablets, USPStrides Pharma Science Limited | Strides Pharma International AG | Strides Pharma, Inc202604086
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE Extended-Release Tablets, for oral use Initial U.S. Approval: 1975A-S Medication Solutions202602175
OXYBUTYNIN CHLORIDE TABLETS, USPHeritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. | Strides Pharma Global Pte. Ltd. | Strides Pharma Science Limited202602163
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE extended-release tablets, for oral use Initial U.S. Approval: 1975PD-Rx Pharmaceuticals, Inc.2026021617
OXYBUTYNIN CHLORIDE TABLETS, USP Rx onlyREMEDYREPACK INC.202602109
Oxybutynin Chloride Oral Solution, USPChartwell Governmental & Specialty RX, LLC.202601301
OXYBUTYNIN CHLORIDE TABLETS, USP Rx onlyPreferred Pharmaceuticals Inc.202601154
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE extended-release tablets for oral use Initial U.S. Approval: 1975Advagen Pharma Limited | Rubicon Research Limited202601148
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE Extended-Release Tablets, for oral use Initial U.S. Approval: 1975A-S Medication Solutions202601143
Oxybutynin Chloride Tablets, USP Rx onlyNorthwind Health Company, LLC202601014
OXYBUTYNIN CHLORIDE TABLETS, USP Rx onlyNorthwind Health Company, LLC202512262
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE extended-release tablets for oral use Initial U.S. Approval: 1975Coupler LLC | Ajanta Pharma Limited202512242
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE extended-release tablets for oral use Initial U.S. Approval: 1975Coupler LLC | Ajanta Pharma Limited202512242
Oxybutynin Chloride Extended Release Tablets, USP These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS, USP safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS, USP. OXYBUTYNIN CHLORIDE extended-release tablets, USP, for oral use Initial U.S. Approval: 1975Chartwell RX, LLC202512223
Oxybutynin Chloride Extended-Release Tablets USP Rx Only These highlights do not include all the information needed to use Oxybutynin chloride extended-release tablets safely and effectively. See full prescribing information for Oxybutynin chloride extended-release tablets. Oxybutynin chloride extended-release tablets for oral use Initial U.S. Approval: 1975AvKARE202512167
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE extended-release tablets, for oral use Initial U.S. Approval: 1975Accord Healthcare, Inc. | Intas Pharmaceuticals Limited2025121613
Oxybutynin Chloride Tablets, USPUpsher-Smith Laboratories, LLC | Bora Pharmaceuticals, Inc2025121117
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE extended-release tablets for oral use Initial U.S. Approval: 1975Ajanta Pharma USA Inc. | Ajanta Pharma Limited, Paithan202511309
OXYBUTYNIN CHLORIDE TABLETS, USPA-S Medication Solutions202511185
OXYBUTYNIN CHLORIDE TABLETS, USPA-S Medication Solutions202511181
Oxybutynin Chloride Tablets, USP Rx onlyVERITYRX, LLC202510311
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE extended-release tablets, for oral use Initial U.S. Approval: 1975PD-Rx Pharmaceuticals, Inc.2025102044
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE Extended-Release Tablets, for oral use Initial U.S. Approval: 1975PD-Rx Pharmaceuticals, Inc.2025100213
Oxybutynin Chloride Tablets, USP Rx onlyMajor Pharmaceuticals202509194
OXYBUTYNIN CHLORIDE TABLETS, USPPD-Rx Pharmaceuticals, Inc.2025081810
Oxybutynin Chloride Tablets, USP Rx onlyCardinal Health 107, LLC202508183
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE extended-release tablets, for oral use Initial U.S. Approval: 1975Major Pharmaceuticals2025071510
Oxybutynin Chloride Syrup USPATLANTIC BIOLOGICALS CORP.202505233
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE Extended-Release Tablets, for oral use Initial U.S. Approval: 1975Rising Pharma Holdings, Inc. | Unique Pharmaceutical Laboratories2025051912
Oxybutynin Chloride Tablets, USP Rx onlyAvKARE202505011
Oxybutynin Chloride Extended-Release Tablets USP Rx Only These highlights do not include all the information needed to use Oxybutynin chloride extended-release tablets safely and effectively. See full prescribing information for Oxybutynin chloride extended-release tablets. Oxybutynin chloride extended-release tablets for oral use Initial U.S. Approval: 1975AvPAK202504178
OXYBUTYNIN CHLORIDE TABLETS, USP Rx onlyPD-Rx Pharmaceuticals, Inc.2025031214
OXYBUTYNIN CHLORIDE TABLETS, USP Rx onlyPD-Rx Pharmaceuticals, Inc.2025030715
OXYBUTYNIN CHLORIDE TABLETS, USPPD-Rx Pharmaceuticals, Inc.202502279
Oxybutynin Chloride Oral Solution, USPChartwell RX, LLC202502262
OXYBUTYNIN CHLORIDE TABLETS, USP Rx onlyBryant Ranch Prepack202501305
Oxybutynin Chloride Tablets, USPRedpharm Drug202501232
OXYBUTYNIN CHLORIDEDIRECT RX202501172
OXYBUTYNIN CHLORIDEdirect rx202501173
Oxybutynin Chloride Tablets, USP Rx onlyGolden State Medical Supply, Inc.202412236
OXYBUTYNIN CHLORIDE TABLETS, USP Rx onlyKVK-Tech, Inc. | ABHAI LLC202412068
OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETSZydus Lifesciences Limited202412038
Oxybutynin Chloride Tablets, USP Rx onlyANI Pharmaceuticals, Inc. | Novitium Pharma LLC202411254
Oxybutynin Chloride Tablets, USP Rx OnlyAphena Pharma Solutions - Tennessee, LLC202410101
OXYBUTYNIN CHLORIDE TABLETS USPBryant Ranch Prepack202410035
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE extended-release tablets, USP, for oral use Initial U.S. Approval: 1975American Health Packaging2024092612
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE extended-release tablets, for oral use Initial U.S. Approval: 1975NCS HealthCare of KY, LLC dba Vangard Labs202409139
Oxybutynin Chloride Tablets, USPTeva Pharmaceuticals USA, Inc.2024090215
Drug FactsAllergan, Inc.202408157
Oxybutynin Chloride Tablets, USP 5 mg Rx onlyNuCare Pharmaceuticals,Inc.202408143
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE extended-release tablets, for oral use Initial U.S. Approval: 1975NCS HealthCare of KY, LLC dba Vangard Labs2024081211
OXYBUTYNIN CHLORIDE TABLETS, USPBryant Ranch Prepack202408095
OXYBUTYNIN CHLORIDE TABLETS, USPRISING PHARMA HOLDINGS, INC. | Appco Pharma LLC202407038
OXYBUTYNIN CHLORIDE TABLETS, USP Rx onlyA-S Medication Solutions2024060311
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE extended-release tablets, for oral use Initial U.S. Approval: 1975A-S Medication Solutions202406039
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE extended-release tablets, for oral use Initial U.S. Approval: 1975A-S Medication Solutions2024060310
These highlights do not include all the information needed to use OXYTROL safely and effectively. See full prescribing information for OXYTROL. OXYTROL ® (oxybutynin transdermal system) Initial U.S. Approval: 1975Allergan, Inc.202405298
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE Extended-Release Tablets USP, for oral use Initial U.S. Approval: 1975Bryant Ranch Prepack20240524102
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE Extended-Release Tablets, for oral use Initial U.S. Approval: 1975Proficient Rx LP202404011
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE Extended-Release Tablets, for oral use Initial U.S. Approval: 1975Bryant Ranch Prepack20240118100
Oxybutynin Chloride Tablets, USP Rx onlyA-S Medication Solutions202312271
Oxybutynin Chloride Tablets, USP Rx onlyA-S Medication Solutions202312271
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE extended-release tablets, for oral use Initial U.S. Approval: 1975Zydus Pharmaceuticals USA Inc. | Zydus Lifesciences Limited202311077
Oxybutynin Chloride Tablets, USPA-S Medication Solutions202311013
Oxybutynin Chloride Tablets, USPNCS HealthCare of KY, LLC dba Vangard Labs202310041
Oxybutynin Chloride Extended-Release Tablets USP Rx Only These highlights do not include all the information needed to use Oxybutynin chloride extended-release tablets safely and effectively. See full prescribing information for Oxybutynin chloride extended-release tablets. Oxybutynin chloride extended-release tablets for oral use Initial U.S. Approval: 1975Aphena Pharma Solutions - Tennessee, LLC202305312
Oxybutynin Chloride Tablets, USP Rx onlyAphena Pharma Solutions - Tennessee, LLC202305312
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE extended-release tablets, for oral use Initial U.S. Approval: 1975Lannett Company, Inc.2023053042
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE extended-release tablets, for oral use Initial U.S. Approval: 1975A-S Medication Solutions202302065
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE extended-release tablets, for oral use Initial U.S. Approval: 1975Amneal Pharmaceuticals LLC | Amneal Pharmaceuticals of New York, LLC2023020219
Oxybutynin Chloride Tablets, USP (PLD)Aphena Pharma Solutions - Tennessee, LLC202301043
Oxybutynin Chloride Tablets, USP (PLD)TruPharma LLC | Tulex Pharmaceuticals, Inc.202211175
OXYBUTYNIN CHLORIDE TABLETS USPProficient Rx LP202206015
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE extended-release tablets, for oral use Initial U.S. Approval: 1975Proficient Rx LP202206011
Oxybutynin Chloride Tablets, USPLeading Pharma, LLC | LIFEPharma FZE202202148
4eb9441b-27ba-1b8f-e054-00144ff88e88RedPharm Drug, Inc.202201203
Oxybutynin Chloride Tablets, USP Rx onlyBryant Ranch Prepack202112282
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE extended-release tablets, USP, for oral use Initial U.S. Approval: 1975A-S Medication Solutions202106166
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE extended-release tablets, for oral use Initial U.S. Approval: 1975A-S Medication Solutions202106143
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE extended-release tablets, for oral use Initial U.S. Approval: 1975A-S Medication Solutions202106145
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE extended-release tablets, for oral use Initial U.S. Approval: 1975A-S Medication Solutions202106146
OXYBUTYNIN CHLORIDE SYRUP, USP 5 mg/5 mLAtlantic Biologicals Corps202101274
Oxybutynin Chloride Syrup USPLannett Company, Inc.2020022124
Oxybutynin Chloride Tablets, USP 5 mg Rx onlyDenton Pharma, Inc. DBA Northwind Pharmaceuticals202001301
OXYBUTYNIN CHLORIDE TABLETS, USPAphena Pharma Solutions - Tennessee, LLC201912182
Oxybutynin Chloride TabletsMarlex Pharmaceuticals Inc201910182
These highlights do not include all the information needed to use oxybutynin chloride extended-release tablets safely and effectively. See full prescribing information for oxybutynin chloride extended-release tablets. OXYBUTYNIN chloride extended-release tablets, USP for oral use. Initial U.S. Approval: 1975Aphena Pharma Solutions - Tennessee, LLC201910101
OXYBUTYNIN CHLORIDE TABLETS, USP Rx onlyDOH CENTRAL PHARMACY201901221
Oxybutynin Chloride Tablets, USPAidarex Pharmaceuticals LLC | Aidarex Pharmaceuticals201808131
OXYBUTYNIN CHLORIDE SYRUP, USP 5 mg/5 mLCarilion Materials Management201802064
These highlights do not include all the information needed to use Oxybutynin chloride extended-release tablets safely and effectively. See full prescribing information for Oxybutynin chloride extended-release tablets. Oxybutynin chloride extended-release tablets for oral use Initial U.S. Approval: 1975Aphena Pharma Solutions - Tennessee, LLC201710201
These highlights do not include all the information needed to use oxybutynin chloride extended-release tablets safely and effectively. See full prescribing information for oxybutynin chloride extended-release tablets. Oxybutynin Chloride Extended-Release Tablets for oral use Initial U.S. Approval: 1975Carilion Materials Management201608063
OXYBUTYNIN CHLORIDE TABLETS, USPAphena Pharma Solutions - Tennessee, LLC201606151
These highlights do not include all the information needed to use oxybutynin chloride extended-release tablets safely and effectively. See full prescribing information for oxybutynin chloride extended-release tablets. OXYBUTYNIN chloride extended-release tablets, USP for oral use. Initial U.S. Approval: 1975Marlex Pharmaceuticals Inc201602133
These highlights do not include all the information needed to use OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS safely and effectively. See full prescribing information for OXYBUTYNIN CHLORIDE EXTENDED-RELEASE TABLETS. OXYBUTYNIN CHLORIDE extended-release tablets, USP for oral use Initial U.S. Approval: 1975Avera McKennan Hospital201601081
OXYBUTYNIN CHLORIDE TABLETS, USPBlenheim Pharmacal, Inc.201512221
OXYBUTYNIN CHLORIDE SYRUP (OXYBUTYNIN CHLORIDE ORAL SOLUTION, USP 5 mg per 5 mL)Atlantic Biologicals Corps201505032
These highlights do not include all the information needed to use oxybutynin chloride extended-release tablets safely and effectively. See full prescribing information for oxybutynin chloride extended-release tablets. Oxybutynin Chloride Extended-Release Tablets for oral use Initial U.S. Approval: 1975Bryant Ranch Prepack201503201001
OXYBUTYNIN CHLORIDE Tablets USPBlenheim Pharmacal, Inc.201502251
OXYBUTYNIN CHLORIDE TABLETS, USPAidarex Pharmaceuticals LLC201401211
OXYBUTYNIN CHLORIDE EXTENDED RELEASE TABLETS, 5 MG, 10 MG AND 15 MGDispensing Solutions, Inc. | PSS World Medical, Inc.201310301
OXYBUTYNIN CHLORIDE TABLETS, USPState of Florida DOH Central Pharmacy201309261
OXYBUTYNIN CHLORIDE Tablets USPPhysicians Total Care, Inc.201303184
Oxybutynin Chloride Extended-Release Tablets USPAphena Pharma Solutions - Tennessee, Inc. | Kremers Urban Pharmaceuticals Inc.201203262
DITROPAN XL ® (oxybutynin chloride) Extended Release TabletsPhysicians Total Care, Inc.201202161
OXYBUTYNIN CHLORIDE TABLETS, USPState of Florida DOH Central Pharmacy201006071
Oxybutynin Chloride Tablets, USPState of Florida DOH Central Pharmacy201006071
82c40f61-91a1-4946-b63f-0251aa01740cPhysicians Total Care, Inc.201001211
fb54818b-efdd-4d08-9fd0-64f903180220Physicians Total Care, Inc.201001211
These highlights do not include all the information needed to use GELNIQUE safely and effectively. See full prescribing information for GELNIQUE. GELNIQUE (oxybutynin chloride) gel for topical use Initial U.S. Approval: 1975Physicians Total Care, Inc.200901151
3544f362-07fc-93b1-457b-1fba00be087a-2