Tacrus by is a Prescription medication manufactured, distributed, or labeled by Pella Pharmaceuticals Co. Ltd. Drug facts, warnings, and ingredients follow.
The active substance of Tacrus
®, tacrolimus monohydrate, is an immune-modulating agent.
Tacrus ® 0.03% ointment is used to treat moderate to severe atopic dermatitis (eczema) in adults who are not adequately responsive to or are intolerant of conventional therapies such as topical corticosteroids and in children (2 years of age and older) who failed to respond adequately to conventional therapies such as topical corticosteroids. Tacrus ® 0.1 % ointment is used to treat moderate to severe atopic dermatitis (eczema) in adults who are not adequately responsive to or are intolerant of conventional therapies such as topical corticosteroids.
Once moderate to severe atopic dermatitis is cleared or almost cleared after up to 6 weeks treatment of a flare, and if you are experiencing frequent flares (i.e. 4 oc more per year), it may be possible to prevent flares coming back or prolong the time you are free from flares by using Tacrus ® 0.1% ointment twice weekly.
In atopic dermatitis, an over-reaction of the skin's immune system causes skin inflammation (itchiness, redness, dryness).
Tacrus ® alters the abnormal immune response and relieves the skin inflammation and the itch.
If you are allergic (hypersensitive) to tacrolimus or any of other ingredients of Tacrus or to macrolide anttbiotics (e.g. azithromycin, clarithromycin, erythromycin).
Tell your doctor if you:
Don't use Tacrus
® if you are breast-feeding.
Ask your doctor or pharmacist before taking any medicine.
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
You may use moisturizing creams and lotions during treatment with Tacrus® but these products should not be used within two hours of applying Tacrus ®.
The use of Tacrus ® at the same time as other preparations to be used on the skin or while taking oral corticosteroids (e.g. cortisone) or medicines which affect the immune system has not been studied.
Using Tacrus ® with food and drink
While using Tacrus ®, drinking alcohol may cause the skin or face to become flushed or red and feel hot.
Always use Tacrus ® exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.
Children (2 years of age and older):
Apply Tacrolimus 0.03% ointment twice a day for up to three weeks, once in the morning and once in the evening. Afterwards the ointment should be used once a day on each affected region of the skin until the eczema has gone away.
Adults (16 years of agc and older):
Two strengths of Tacrolimus (0.03% and 0.1% ointment) are available for adults patients (16 years of age and older). Your doctor will decide which strength is best for you.
Usually, treatment is started with Tacrus ® 0.1% ointment twice a day, once in the morning and once in the evening, until the eczema has cleared. Depending on the response of your eczema your doctor will decide if the frequency of application can be reduced or the lower strength, Tacrolimus 0.03% ointment, can be used.
Treat each affected region of your skin until the eczema has gone away. Improvement is usually seen within one week. If you do not see any improvement after two weeks, see your doctor about other possible treatments. You may be told by your doctor to use Tacrus ® 0.1% ointment twice weekly once your atopic dermatitis has cleared or almost cleared (Tacrolimus 0.03% for children and Tacrs ® 0.1% for adults). Tacrus ® 0.1% ointment should be applied once a day twice weekly (e.g. Monday and Thursday) to areas of your body commonly affected by atopic dermatitis. There should be 2-3 days without Tacrus ® treatment between applications.
If symptoms reappear you should use Tacrus ® twice daily as outlined above and arrange to see your doctor to review your treatment.
Like all medicines, Tacrus ® can cause side effects, although not everybody gets them.
Very common (probably affecting more than 1 in 10): burning sensation and itching; these symptoms are usually mild to moderate and generally go away within one week of using Tacrus ®.
Following twice-weekly treatment application site infections have been reported in children and adults, impetigo, a superficial bacterial skin infection that usually produces blisters or sores on the skin,has been reported in children. Rosaceae (facial redness), Rosaceae- like dermatitis and oedema at the application site has been reported during post marketing experience.
Since commercial availability a very small number of people who have used Tacrolimus ointment have had malignancies (for example, skin and lymphoma). However a link to Tacrolimus ointment has not been confirmed or refuted on the available evidence so far.
If any of the side effects gets serious, or if you notice any side effect not listed in this leaflet, please tell your doctor or pharmacist.
If you accidentaly swallow some ointment
If you accidentally swallow the ointment, consult your doctor or pharmacist as soon as possible. Do not try to induce Vomiting.
If you forget to use Tacrus ®
If you forget to apply the ointment at the scheduled time, do it as soon as you remember and then continue as before. If you have any further questions on the use of this product, ask your doctor or pharmacist.
|Labeler - Pella Pharmaceuticals Co. Ltd (562370925)|