Identity: CRISPR-Cas editing with homology dependent repair in cattle to introduce two copies of the Celtic allele of Bos taurus chromosome 1 (NC_037328.1). The intended mutations resulted in presence of a known polled genotype variation already present within the species.
HEALTH CLAIM SECTION
Claim: The homozygous Celtic allele will allow the introduction of a polled phenotype into horned cattle.
INDICATIONS & USAGE SECTION
Product Use: Founder animals are intended for production and sale of semen to enable the establishment of polled herds, the progeny of which will be used as a food source.