Citrate anticoagulation solution

Definition

A citric acid (citrate) formulation introduced into the extracorporeal circuit of a dialysis system to inhibit the coagulation of blood, typically during continuous renal replacement therapy (CRRT) - physiological dialysis performed over a 24-hour period or longer. Citrate inhibits coagulation by binding with calcium and rendering calcium unavailable to the clotting cascade. When blood from the extracorporeal circuit is returned to the patient it mixes with central venous blood which contains calcium that has been continuously administered to the patient, and the anticoagulant effect is neutralized. It is typically supplied in a polyvinyl chloride (PVC) bag. This is a single-use device.

GUDID devices

4

Last updated

2020-03-17 21:37:35