A collection of devices intended to be used during cold plasma antifog activation of an endoscope by providing: 1) a physical barrier between an endoscope cold plasma antifogging unit and the endoscope/sterile field; and 2) an antifog solution to complement cold plasma treatment. It includes a plastic drape with a dedicated plug-in component intended to shield the internal portion of the antifogging unit, and an antifog solution typically with an application sponge. This is a single-use device.