sam 3.0 multi-hour continuous ultrasound device for home use

Primary DI
00857599005325
Brand
sam 3.0 multi-hour continuous ultrasound device for home use
Company
ZETROZ SYSTEMS, LLC
Model
OA325
Device description
Sustained Acoustic Medicine SAM 3.0 OA325 multi-hour continuous ultrasound device is FDA-cleared for prescription home use to apply high-frequency (3MHz), high-dosimetry (1.3W, 18,720J) ultrasonic energy to generate and sustain deep non-thermal (mechanotransducive) and thermal (vigorous diathermy @ 44C) for the relief of pain associated with limited mobility and function related to soft tissue injuries including knee osteoarthritis, chronic myofascial pain, and shoulder, elbow and ankle tendinopathy. The SAM 3.0 innovation improves battery life and includes faster charging (USB-C) and high fidelity LEDs. This device introduces dual independently operated SAM zone regulation for maximum acoustic streaming and deep tissue stimulation over a sustained 4-hour period, with battery life extended over 8 hours. These are attached to the treatment site with ultrasonic coupling devices to allow for wearability, active daily use, and articulation on the body. The preset frequency, intensity and clinically proven therapeutic parameters cannot be modified by the user. This treatment algorithm provides thermal and mechanical stimulation into deep tissue (5-10 cm), to increase local circulation, stimulate cellular proliferation, improve joint lubricity, reduce inflammation, and relieve pain in the arthritic joint. SAM 3.0 OA325 is certified by the U.S. Arthritis Foundation for Ease-of-Use for arthritis patients with chronic joint pain. The basic science, clinical design efforts, human-factor validations, level I clinical studies and regulatory approvals are supported by the National Institutes of Health program wide initiative of Helping to End Opioid Addiction Long-Term® (NIH HEAL) and the National Institutes on Aging research programs for patients with chronic arthritis pain.
Published
2026-06-23
Public version status
New
Distribution status
In Commercial Distribution
MRI safety
MR Unsafe
Rx
true
OTC
false
Sterile
false
Single use
false

Product Codes#

Code, Name table
CodeName
PFWStationary Ultrasonic Diathermy Device For Use In Applying Therapeutic Deep Heat

Product Code Classifications#

Code, Device, Specialty table
CodeDeviceSpecialtyClass
PFWStationary Ultrasonic Diathermy Device For Use In Applying Therapeutic Deep HeatPhysical Medicine2

Premarket Submissions#

Submission, Supplement table
SubmissionSupplement
K260076000

Premarket Details#

Submission, Supplement, Device table
SubmissionSupplementDeviceApplicantDecision dateProduct code
K260076000SAM 3.0 Multi-Hour Continuous Ultrasound DeviceZetrOZ Systems, LLC2026-04-28PFW

Identifiers And Packaging#

Identifier, Type, Agency table
IdentifierTypeAgencyPackage quantityStatus
00857599005325PrimaryGS10

Alternate GTIN / UPC / EAN Codes

Source identifier, GTIN-14 normalized, UPC-A table
Source identifierGTIN-14 normalizedUPC-AEAN-13
00857599005325008575990053258575990053250857599005325

GMDN Terms#

Term, Definition table
TermDefinition
Physical therapy ultrasound systemAn assembly of devices designed to produce and deliver ultrasonic waves that penetrate tissues and produce both thermal and nonthermal (e.g., mechanical and cavitation) effects to treat pain (e.g., muscle, tendon, joint) and as an aid in the healing of soft-tissue injuries (e.g., ulcerations, bursitis). It typically consists of a radio-frequency (RF) generator (frequencies from one to three megahertz are typical), a cable that transmits the RF energy to the applicator, and an applicator including a piezoelectric transducer that applies the ultrasonic energy to the patient's tissues through the skin.

Regulatory Flags#

DUNS number
080128497
Device count
1
DM exempt
false
Premarket exempt
false
HCT/P
false
Kit
false
Combination product
false
Lot or batch
true
Serial number
true
Manufacturing date on label
true
Expiration date on label
true
Donation ID number
false
Contains natural rubber latex
false
No natural rubber latex
true
Sterilization required before use
false

Other Devices From This Company#

Primary DI, Brand, Model table
Primary DIBrandModelCatalogPublished
00857599005271sam 2.0 OA multi-hour continuous ultrasound device for home useSAM 2.0 OA24OA242026-04-07
00857599005257sam(R) Advanced Gel Capture PatchUB-14UB-14-15W2024-10-10
00857599005172sam(R) Advanced Gel Capture PatchUB-14UB14-15T2024-10-10
00857599005097sam coupling patchUB-122016-10-10
00857599005165sam(R) Advanced Gel Capture PatchUB-14UB-14-15W2024-10-10
00857599005202sam X1SA551SA5512022-09-29
00857599005196sam 2.0 Long Duration Ultrasound Device for Home UseSA2712021-11-30
00857599005073samsam-122016-10-10

Other Devices Sharing Product Codes#

Primary DI, Brand, Company table
Primary DIBrandCompanyProduct codePublished
00857599005271sam 2.0 OA multi-hour continuous ultrasound device for home useZETROZ SYSTEMS, LLCPFW2026-04-07
00850033615227Echo Ultrasound Device (PRC) THERMOTEK, INC.PFW2026-02-23
00850033615258Echo Ultrasound Device (PRC)THERMOTEK, INC.PFW2026-02-23
00850033615289Echo Ultrasound Device (USA)THERMOTEK, INC.PFW2026-02-23
00850033615340Echo Ultrasound Device (USA)THERMOTEK, INC.PFW2026-02-23
00850033615371Echo BOX, DRESSING & GEL POD PACK, USND, PRCTHERMOTEK, INC.PFW2026-02-23
00850033615388Echo CTN, DRESSINGS, USND, PRC, QTY 4 BOXESTHERMOTEK, INC.PFW2026-02-23
00850033615425Echo Ultra Sound Gel Pods, CartonTHERMOTEK, INC.PFW2026-02-23
00850033615487Echo Ultra Sound Gel Pod, SingleTHERMOTEK, INC.PFW2026-02-23
00850033615500Echo APPLICATOR, SINGLE, USNDTHERMOTEK, INC.PFW2026-02-23
00850033615517Echo POWER SUPPLY, CORD, SINGLE, USNDTHERMOTEK, INC.PFW2026-02-23
00850033615531Echo BELT CLIP, DEVICE PRTCTR, SNGL,USNDTHERMOTEK, INC.PFW2026-02-23
00850033615555Echo ARM STRAP, DEVICE PRTCTR, SNG, USNDTHERMOTEK, INC.PFW2026-02-23
00850033615562Echo GEL, TUBE, SINGLE, USNDTHERMOTEK, INC.PFW2026-02-23
00850033615586echoRx, MANUAL, USER, SINGLE, USNDTHERMOTEK, INC.PFW2026-02-23
00850033615593echoRx, GUIDE,QUICK START,SNGL,USNDTHERMOTEK, INC.PFW2026-02-23
00850033615623Echo CTN, DRESSINGS, USND, USA, QTY 4 BOXESTHERMOTEK, INC.PFW2026-02-23
00850033615630Echo BOX, DRESSING & GEL POD PACK, USND, USATHERMOTEK, INC.PFW2026-02-23
00810113682778ManaMed Transducer Holder PatchManamed, Inc.PFW2025-09-11
00810113682754ManaMed Transducer Fixation StrapManamed, Inc.PFW2025-09-11
00810113682761ManaMed Transducer Fixation StrapManamed, Inc.PFW2025-09-11
00857599005257sam(R) Advanced Gel Capture PatchZETROZ SYSTEMS, LLCPFW2024-10-10
00857599005172sam(R) Advanced Gel Capture PatchZETROZ SYSTEMS, LLCPFW2024-10-10
00857599005165sam(R) Advanced Gel Capture PatchZETROZ SYSTEMS, LLCPFW2024-10-10
07290103422011PainShield PatchNANOVIBRONIX INC.PFW2023-07-24
07290103421144PainShield 3.0 ActuatorNANOVIBRONIX INC.PFW2023-07-16
07290103421328PainShield Plus Actuator NANOVIBRONIX INC.PFW2023-07-16
07290103422028PainShield 3.0 Driver NANOVIBRONIX INC.PFW2023-07-16
07290103422035PainShield Plus 3.0 Driver NANOVIBRONIX INC.PFW2023-07-16
00857599005202sam X1ZETROZ SYSTEMS, LLCPFW2022-09-29