REFRESH Classic

Product NDC: 0023-0506
11-digit product format: 000230506
Labeler code: 0023
Product ID: 0023-0506_58d49977-1915-4473-801d-a28b87b9a328
Type: HUMAN OTC DRUG
Nonproprietary name: Polyvinyl Alcohol, Povidone
Dosage form: SOLUTION/ DROPS
Route: OPHTHALMIC
Labeler: Allergan, Inc.
Application: M018
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 1985-09-12
Substance: POLYVINYL ALCOHOL, UNSPECIFIED; POVIDONE
Active strength: 14; 6 mg/mL; mg/mL
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: REFRESH Classic
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
POLYVINYL ALCOHOL, UNSPECIFIED	14 mg/mL
POVIDONE	6 mg/mL

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
0023-0506-01	REFRESH Classic	0.4 mL in 1 VIAL, SINGLE-USE	SOLUTION/ DROPS	0.4	11
0023-0506-01	REFRESH Classic	30 in 1 CARTON	SOLUTION/ DROPS	30	11
0023-0506-50	REFRESH Classic	50 in 1 CARTON	SOLUTION/ DROPS	50	11
0023-0506-50	REFRESH Classic	0.4 mL in 1 VIAL, SINGLE-USE	SOLUTION/ DROPS	0.4	11

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
0023-0506-01	EA - Each	0023-0506	6f103f52-b51b-4112-8b6f-0dbff9ac462a	1	2012-07-24
0023-0506-50	EA - Each	0023-0506	d349c8e5-b120-43bc-a75d-eb0c165a554e	1	2012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
Polyvinyl Alcohol	ACTIVE INGREDIENT	532B59J990	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	4
Povidone	ACTIVE INGREDIENT	FZ989GH94E	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	4
Polyvinyl Alcohol	ACTIVE MOIETY	532B59J990	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	4
Povidone	ACTIVE MOIETY	FZ989GH94E	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	4
hydrochloric acid	INACTIVE INGREDIENT	QTT17582CB	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	4
sodium chloride	INACTIVE INGREDIENT	451W47IQ8X	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	4
sodium hydroxide	INACTIVE INGREDIENT	55X04QC32I	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	4
water	INACTIVE INGREDIENT	059QF0KO0R	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	4

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
0023-0506	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	10	Current NDC, Legacy NDC, 4 package rows	20240214_31bf1d6c-9719-4060-b6a3-409a2fe7b560.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 20 of 25 · 494 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Clear Eyes Natural Tears	POLYVINYL ALCOHOL AND POVIDONE	Prestige Brands Holdings, Inc.	efba3eb0-798d-4635-b19b-4970e45b3cc9	2024-04-01	Warnings	Exact identifier application number: M018
Polyvinyl Alcohol	POLYVINYL ALCOHOL	A-S Medication Solutions	c77589fd-f68d-48b7-bd12-51f6b4cc9402	2024-03-20	Warnings	Exact identifier application number: M018
REFRESH CLASSIC	POLYVINYL ALCOHOL, POVIDONE	A-S Medication Solutions	3bf6193c-56db-45ad-844c-58eb8c33cba9	2024-03-14	Warnings	Exact identifier application number: M018
GOODSENSE ARTIFICIAL TEARS	POLYVINYL ALCOHOL	Proficient Rx LP	f29c792c-6cb2-449f-b97d-6304a58dec2a	2024-02-01	Warnings	Exact identifier application number: M018
GoodSense Artifical Tears	POLYVINYL ALCOHOL, AND POVIDONE	Proficient Rx LP	cd24da78-fd90-4a9c-8e5f-f7fc56ec0fc9	2024-02-01	Warnings	Exact identifier application number: M018
GENTEAL TEARS	DEXTRAN 70, GLYCERIN, HYPROMELLOSE	A-S Medication Solutions	a2b715e9-332d-4f0b-b8e5-ebc000681586	2024-01-21	Warnings	Exact identifier application number: M018
Visine Red Eye Hydrating Comfort, CVP	TETRAHYDROZOLINE HYDROCHLORIDE AND POLYETHYLENE GLYCOL 400 SOLUTION/ DROPS	Lil' Drug Store Products, Inc.	0f50bcc8-3658-8c2c-e063-6294a90a8e13	2024-01-19	Warnings	Exact identifier application number: M018
Fendall 2000 Pure Flow	PURIFIED WATER	Honeywell Safety Products USA, Inc.	b56ef662-fec2-4d94-e053-2995a90aba2b	2024-01-06	Warnings	Exact identifier application number: M018
Exchange Select Maximum Redness Relief Eye Drops	GLYCERIN, NAPHAZOLINE HCL	Army and Air Force Exchange Service	318bc025-c936-a066-e063-6294a90a4712	2024-01-01	Warnings	Exact identifier application number: M018
Kroger Eye Drops Original	TETRAHYDROZOLINE HCL	The Kroger Co.	318c17a1-fe08-508b-e063-6394a90a2e08	2024-01-01	Warnings	Exact identifier application number: M018
HEB Original Eye Drops	TETRAHYDROZOLINE HCL	HEB Grocery Company, LP	318cb457-bb2d-a1ee-e063-6294a90a8019	2024-01-01	Warnings	Exact identifier application number: M018
Discount Drug Mart Eye Drops Multi-Symptom Relief	POLYETHYLENE GLYCOL 400, TETRAHYDROZOLINE HCL, ZINC SULFATE	Discount Drug Mart, Inc.	318dc92a-0707-d6a4-e063-6294a90ab78a	2024-01-01	Warnings	Exact identifier application number: M018
Kroger Eye Drops Redness Relief	GLYCERIN, NAPHAZOLINE HYDROCHLORIDE	The Kroger Co.	318dea21-2656-36a3-e063-6294a90ac9c4	2024-01-01	Warnings	Exact identifier application number: M018
Harris Teeter Eye Drops Original	TETRAHYDROZOLINE HCL	Harris Teeter, LLC.P	31a1b962-27ad-97b1-e063-6294a90a77f1	2024-01-01	Warnings	Exact identifier application number: M018
CVP Sterile Eye Drops	TETRAHYDROZOLINE HCL	Salado Sales, Inc.	31a216f8-28e9-ec8f-e063-6394a90aec49	2024-01-01	Warnings	Exact identifier application number: M018
Equaline Sterile Eye Drops	TETRAHYDROZOLINE HCL	United Natural Foods, Inc.	31a25efb-a627-1a13-e063-6394a90a2ca3	2024-01-01	Warnings	Exact identifier application number: M018
Best Choice Eye Drops Original	TETRAHYDROZOLINE HCL	Valu Merchandisers Company	31a2a42a-bcfe-4f22-e063-6294a90ac60e	2024-01-01	Warnings	Exact identifier application number: M018
Discount Drug Mart Eye Drops Original	TETRAHYDROZOLINE HCL	Discount Drug Mart, Inc.	31a2efb2-3924-6a12-e063-6394a90ab0e2	2024-01-01	Warnings	Exact identifier application number: M018
Equaline Redness Relief Lubricant Eye Drops	GLYCERIN, NAPHAZOLINE HYDROCHLORIDE	United Natural Foods, Inc	31a30b00-9f4b-717a-e063-6394a90a8a87	2024-01-01	Warnings	Exact identifier application number: M018
Harris Teeter Redness Relief Eye Drops	GLYCERIN, NAPHAZOLINE HYDROCHLORIDE	Harris Teeter, LLC.	31a3d575-10f1-5feb-e063-6294a90ac478	2024-01-01	Warnings	Exact identifier application number: M018

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
532B59J990	POLYVINYL ALCOHOL, UNSPECIFIED	9002-89-5	POLYVINYL ALCOHOL, UNSPECIFIED

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
359969	polyvinyl alcohol 1.4 % / povidone 0.6 % Ophthalmic Solution	PSN	3bf6193c-56db-45ad-844c-58eb8c33cba9	18
359969	polyvinyl alcohol 0.014 ML/ML / povidone 6 MG/ML Ophthalmic Solution	SCD	3bf6193c-56db-45ad-844c-58eb8c33cba9	18
359969	polyvinyl alcohol 1.4 % / povidone 0.6 % Ophthalmic Solution	SY	3bf6193c-56db-45ad-844c-58eb8c33cba9	18
359969	polyvinyl alcohol 1.4 % / povidone 0.6 % Ophthalmic Solution	PSN	31bf1d6c-9719-4060-b6a3-409a2fe7b560	11
359969	polyvinyl alcohol 0.014 ML/ML / povidone 6 MG/ML Ophthalmic Solution	SCD	31bf1d6c-9719-4060-b6a3-409a2fe7b560	11
359969	polyvinyl alcohol 1.4 % / povidone 0.6 % Ophthalmic Solution	SY	31bf1d6c-9719-4060-b6a3-409a2fe7b560	11

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Marketing start	Marketing end	Sample	Exclude flag	Status
0023-0506-01	00023050601	30 VIAL, SINGLE-USE in 1 CARTON (0023-0506-01) / .4 mL in 1 VIAL, SINGLE-USE	1985-09-12	0000-00-00	No	No	Current
0023-0506-50	00023050650	50 VIAL, SINGLE-USE in 1 CARTON (0023-0506-50) / .4 mL in 1 VIAL, SINGLE-USE	1985-09-12	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
REFRESH ® Classic ( P reservative-free ) Drug Facts	Allergan, Inc.	2026-09-15	HUMAN OTC DRUG LABEL	12
REFRESH CLASSIC	A-S Medication Solutions	2024-03-14	HUMAN OTC DRUG LABEL	18