REFRESH Classic

Product NDC: 0023-0506
11-digit product format: 000230506
Labeler code: 0023
Product ID: 0023-0506_58d49977-1915-4473-801d-a28b87b9a328
Type: HUMAN OTC DRUG
Nonproprietary name: Polyvinyl Alcohol, Povidone
Dosage form: SOLUTION/ DROPS
Route: OPHTHALMIC
Labeler: Allergan, Inc.
Application: M018
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 1985-09-12
Substance: POLYVINYL ALCOHOL, UNSPECIFIED; POVIDONE
Active strength: 14; 6 mg/mL; mg/mL
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: REFRESH Classic
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
POLYVINYL ALCOHOL, UNSPECIFIED	14 mg/mL
POVIDONE	6 mg/mL

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
0023-0506-01	REFRESH Classic	0.4 mL in 1 VIAL, SINGLE-USE	SOLUTION/ DROPS	0.4	11
0023-0506-01	REFRESH Classic	30 in 1 CARTON	SOLUTION/ DROPS	30	11
0023-0506-50	REFRESH Classic	50 in 1 CARTON	SOLUTION/ DROPS	50	11
0023-0506-50	REFRESH Classic	0.4 mL in 1 VIAL, SINGLE-USE	SOLUTION/ DROPS	0.4	11

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
0023-0506-01	EA - Each	0023-0506	6f103f52-b51b-4112-8b6f-0dbff9ac462a	1	2012-07-24
0023-0506-50	EA - Each	0023-0506	d349c8e5-b120-43bc-a75d-eb0c165a554e	1	2012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
Polyvinyl Alcohol	ACTIVE INGREDIENT	532B59J990	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	4
Povidone	ACTIVE INGREDIENT	FZ989GH94E	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	4
Polyvinyl Alcohol	ACTIVE MOIETY	532B59J990	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	4
Povidone	ACTIVE MOIETY	FZ989GH94E	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	4
hydrochloric acid	INACTIVE INGREDIENT	QTT17582CB	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	4
sodium chloride	INACTIVE INGREDIENT	451W47IQ8X	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	4
sodium hydroxide	INACTIVE INGREDIENT	55X04QC32I	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	4
water	INACTIVE INGREDIENT	059QF0KO0R	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	4

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
0023-0506	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	10	Current NDC, Legacy NDC, 4 package rows	20240214_31bf1d6c-9719-4060-b6a3-409a2fe7b560.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 9 of 25 · 494 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Medics Choice Lubricant Eye Drops	CARBOXYMETHYLCELLULOSE SODIUM	K.C. Pharmaceuticals, Inc.	9ddfc275-602f-413b-e053-2995a90a11cb	2025-12-30	Warnings	Exact identifier application number: M018
Medics Choice Eye Drops Seasonal Relief	TETRAHYDROZOLINE HYDROCHLORIDE, ZINC SULFATE	KC Pharmaceuticals, Inc.	92bd8cb4-90ad-4a47-afa4-30d1fa658d62	2025-12-30	Warnings	Exact identifier application number: M018
DG Health Advanced Relief Eye Drops	DEXTRAN 70, POLYETHYLENE GLYCOL 400, POVIDONE, TETRAHYDROZOLINE HCL	Dolgencorp LLC	9c62f8a3-7cf5-40f9-e053-2a95a90afd86	2025-12-30	Warnings	Exact identifier application number: M018
Medics Choice Eye Drops Original Redness Reliever	TETRAHYDROZOLINE HYDROCHLORIDE	KC Pharmaceuticals, Inc.	e42cb1bf-b985-4a1b-9a9b-ac27c2a5d7be	2025-12-30	Warnings	Exact identifier application number: M018
Medics Choice Eye Drops Maximum Redness Relief	GLYCERIN, NAPHAZOLINE HYDROCHLORIDE	K.C. Pharmaceuticals, Inc.	f7131707-47af-d70a-e053-6394a90a418f	2025-12-30	Warnings	Exact identifier application number: M018
DG Original Eye Drops	TETRAHYDROZOLINE HCL	Dolgencorp LLC	9cb2123c-3ed4-ce8f-e053-2995a90a0ab8	2025-12-30	Warnings	Exact identifier application number: M018
Artificial Tears	POLYVINYL ALCOHOL, POVIDONE	KC Pharmaceuticals, Inc.	eb6eb6c4-1609-407b-84e4-c7509811f3c0	2025-12-30	Warnings	Exact identifier application number: M018
Medics Choice Eye Drops Advanced	TETRAHYDROZOLINE HYDROCHLORIDE, POLYETHYLENE GLYCOL 400, DEXTRAN 70, POVIDONE	KC Pharmaceuticals, Inc.	ab906fd8-265c-4359-a920-d626366e245c	2025-12-30	Warnings	Exact identifier application number: M018
Medics Choice Fresh and Soothe Lubricant Eye Drops	POLYETHYLENE GLYCOL 400, PROPYLENE GLYCOL	KC Pharmaceuticals, Inc.	1f65b91a-4eac-65c2-e063-6394a90a0295	2025-12-30	Warnings	Exact identifier application number: M018
DG Health Dry Eye Relief	GLYCERIN, HYPROMELLOSE, POLYPROPYLENE GLYCOL 400	Dolgencorp LLC	9cb20c3b-bf6d-8c7c-e053-2995a90aa485	2025-12-30	Warnings	Exact identifier application number: M018
DG Lubricant Eye Drops	POLYETHYLENE GLYCOL 400, PROPYLENE GLYCOL	Dolgencorp LLC	9cb27899-6c36-3c37-e053-2995a90a1d43	2025-12-30	Warnings	Exact identifier application number: M018
Publix Artificial Tears Eye Drops	POLYVINYL ALCOHOL, POVIDONE	Publix Super Markets, Inc.	f5d1394b-0fe8-c372-e053-2a95a90a1f78	2025-12-30	Warnings	Exact identifier application number: M018
Best Choice Artificial Tears	POLYVINYL ALCOHOL, POVIDONE	Best Choice	f5ba63f3-7966-81fe-e053-2995a90a342c	2025-12-30	Warnings	Exact identifier application number: M018
DG Maximum Strength Redness Relief	GLYCERIN, NAPHAZOLINE HCL	Dolgencorp, Inc	9cb261ed-b708-1189-e053-2a95a90a547d	2025-12-30	Warnings	Exact identifier application number: M018
Publix Advanced Relief Eye Drops	DEXTRAN 70, POLYETHYLENE GLYCOL 400, POVIDONE, TETRAHYDROZOLINE HYDROCHLORIDE	Publix Super Markets, Inc.	f7b0c3d6-0324-46c3-e053-6394a90a8241	2025-12-30	Warnings	Exact identifier application number: M018
Publix Moisturizing Relief Eye Drops	CARBOXYMETHYLCELLULOSE SODIUM	Publix Super Markets, Inc.	9b391400-c53b-7c7b-e053-2995a90a2731	2025-12-30	Warnings	Exact identifier application number: M018
Publix High Performance Eye Drops	POLYETHYLENE GLYCOL 400, PROPYLENE GLYCOL	Publix Super Markets, Inc.	9b402aa8-87cb-3928-e053-2995a90afa3c	2025-12-30	Warnings	Exact identifier application number: M018
Kroger Eye Drops Artificial Tears	POLYVINYL ALCOHOL, POVIDONE	The Kroger Company	f76f08c5-0111-8bc5-e053-6294a90a16ee	2025-12-30	Warnings	Exact identifier application number: M018
Health Mart Lubricating Tears	POLYETHYLENE GLYCOL 400, PROPYLENE GLYCOL	Strategic Sourcing Services LLC	c8be678f-2b4a-4d39-9cb4-910d36d72174	2025-12-30	Warnings	Exact identifier application number: M018
Winco Maximum Redness Relief Eye Drops	GLYCERIN, NAPHAZOLINE HCL	WinCo Foods, LLC	ff3651d4-42ce-4db1-a318-15f7592baf86	2025-12-30	Warnings	Exact identifier application number: M018

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
532B59J990	POLYVINYL ALCOHOL, UNSPECIFIED	9002-89-5	POLYVINYL ALCOHOL, UNSPECIFIED

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
359969	polyvinyl alcohol 1.4 % / povidone 0.6 % Ophthalmic Solution	PSN	3bf6193c-56db-45ad-844c-58eb8c33cba9	18
359969	polyvinyl alcohol 0.014 ML/ML / povidone 6 MG/ML Ophthalmic Solution	SCD	3bf6193c-56db-45ad-844c-58eb8c33cba9	18
359969	polyvinyl alcohol 1.4 % / povidone 0.6 % Ophthalmic Solution	SY	3bf6193c-56db-45ad-844c-58eb8c33cba9	18
359969	polyvinyl alcohol 1.4 % / povidone 0.6 % Ophthalmic Solution	PSN	31bf1d6c-9719-4060-b6a3-409a2fe7b560	11
359969	polyvinyl alcohol 0.014 ML/ML / povidone 6 MG/ML Ophthalmic Solution	SCD	31bf1d6c-9719-4060-b6a3-409a2fe7b560	11
359969	polyvinyl alcohol 1.4 % / povidone 0.6 % Ophthalmic Solution	SY	31bf1d6c-9719-4060-b6a3-409a2fe7b560	11

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Marketing start	Marketing end	Sample	Exclude flag	Status
0023-0506-01	00023050601	30 VIAL, SINGLE-USE in 1 CARTON (0023-0506-01) / .4 mL in 1 VIAL, SINGLE-USE	1985-09-12	0000-00-00	No	No	Current
0023-0506-50	00023050650	50 VIAL, SINGLE-USE in 1 CARTON (0023-0506-50) / .4 mL in 1 VIAL, SINGLE-USE	1985-09-12	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
REFRESH ® Classic ( P reservative-free ) Drug Facts	Allergan, Inc.	2026-09-15	HUMAN OTC DRUG LABEL	12
REFRESH CLASSIC	A-S Medication Solutions	2024-03-14	HUMAN OTC DRUG LABEL	18