VFEND

Product NDC
0049-4190
11-digit product format
000494190
Labeler code
0049
Product ID
0049-4190_8900af3a-ee67-45ff-90d3-253ed740abd4
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
VORICONAZOLE
Dosage form
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
Route
INTRAVENOUS
Labeler
Roerig
Application
NDA021267
Marketing category
NDA
Marketing start
2012-10-24
Substance
VORICONAZOLE
Active strength
10 mg/mL
Pharmacologic classes
Azole Antifungal [EPC], Azoles [CS], Cytochrome P450 2C19 Inhibitors [MoA], Cytochrome P450 2C9 Inhibitors [MoA], Cytochrome P450 3A4 Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N021267-001VFENDVORICONAZOLE200MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2002-05-24

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
N021267-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N021267-001VFEND200MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2002-05-24011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021267-001VFEND200MG/VIALPOWDER / INTRAVENOUSAPRLD, RS2002-05-2431067a03dcf5…
2025-08-23 18:47 UTC2025-08N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-246a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-24fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-24b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-2403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-242680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-245bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-24d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-24d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-2479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-24301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-241e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-248072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-245c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-245d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-244b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-2474a2ff9319b5…
2022-03-09 01:35 UTC2022-03N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-24bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-24782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-2487673890dc5c…
2021-03-12 10:30 UTC2021-03N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-245aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-248869cabd3fbd…
2020-11-12 02:37 UTC2020-11N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-24c0c555d07b60…
2019-12-14 00:12 UTC2019-12N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-243f01610625f2…
2019-09-15 20:21 UTC2019-09N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-24b00525d2431f…
2019-07-19 19:46 UTC2019-07N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-24ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-246a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-241c564ffb4f44…
2023-12-20 04:57 UTC2023-12N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-24ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-24a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-249b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-24a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-243f0d92c62455…
2023-05-13 08:27 UTC2023-05N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-24053a50430f4f…
2023-01-26 05:58 UTC2023-01N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-243bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-243a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-24f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-24e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N021267-001VFEND200MG/VIALINJECTABLE / INTRAVENOUSAPRLD, RS2002-05-24cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N021267-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021267-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08N021267-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021267-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021267-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021267-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021267-001AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021267-001AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021267-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021267-001AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021267-001AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021267-001AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021267-001AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021267-001AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021267-001AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N021267-001AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N021267-001AP14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N021267-001AP174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N021267-001AP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N021267-001AP1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N021267-001AP187673890dc5c…
2021-03-12 10:30 UTC2021-03N021267-001AP15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N021267-001AP18869cabd3fbd…
2020-11-12 02:37 UTC2020-11N021267-001AP1c0c555d07b60…
2019-12-14 00:12 UTC2019-12N021267-001AP13f01610625f2…
2019-09-15 20:21 UTC2019-09N021267-001AP1b00525d2431f…
2019-07-19 19:46 UTC2019-07N021267-001AP1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N021267-001AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N021267-001AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12N021267-001AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N021267-001AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N021267-001AP19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N021267-001AP1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N021267-001AP13f0d92c62455…
2023-05-13 08:27 UTC2023-05N021267-001AP1053a50430f4f…
2023-01-26 05:58 UTC2023-01N021267-001AP13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N021267-001AP13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N021267-001AP1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N021267-001AP1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N021267-001AP1cb3db0bc1861…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021267-001NPP2022-01-295c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N021267-001NPP2022-01-295d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N021267-001NPP2022-01-294b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N021267-001NPP2022-01-2974a2ff9319b5…
2022-03-09 01:35 UTC2022-03N021267-001NPP2022-01-29bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N021267-001NPP2022-01-29782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N021267-001NPP2022-01-2987673890dc5c…
2021-03-12 10:30 UTC2021-03N021267-001NPP2022-01-295aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N021267-001NPP2022-01-298869cabd3fbd…
2020-11-12 02:37 UTC2020-11N021267-001NPP2022-01-29c0c555d07b60…
2019-12-14 00:12 UTC2019-12N021267-001NPP2022-01-293f01610625f2…
2019-09-15 20:21 UTC2019-09N021267-001NPP2022-01-29b00525d2431f…
2019-07-19 19:46 UTC2019-07N021267-001NPP2022-01-29ea99ee380514…
2023-01-26 05:58 UTC2023-01N021267-001NPP2022-01-293bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N021267-001NPP2022-01-293a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N021267-001NPP2022-01-29f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N021267-001NPP2022-01-29e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N021267-001NPP2022-01-29cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
VFEND
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
VORICONAZOLE10 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
JFU09I87TRInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
351209Internal RxNorm lookup
352220Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
08d08721-1f4c-478a-8abf-d9c402d50553Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
1f86875f-c0c9-343f-b96c-14093866e7a9Product name920190409
591c07fa-4d24-4cb9-9efc-86997c696aa7Product name120170602

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0049-4190-01VFEND20 mL in 1 VIAL, SINGLE-USEINJECTION, POWDER, LYOPHILIZED,2033
0049-4190-01VFEND1 in 1 CARTONINJECTION, POWDER, LYOPHILIZED,133

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0049-4190-01EA - Each0049-4190dcbfd635-7a4b-433e-9a17-cc377be531d512013-07-02

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
VORICONAZOLEACTIVE INGREDIENTJFU09I87TRVFEND (VORICONAZOLE) INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION [ROERIG]7
VORICONAZOLEACTIVE MOIETYJFU09I87TRVFEND (VORICONAZOLE) INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION [ROERIG]7
SULFOBUTYLETHER .BETA.-CYCLODEXTRININACTIVE INGREDIENT2PP9364507VFEND (VORICONAZOLE) INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION [ROERIG]7

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0049-4190VFEND (VORICONAZOLE) INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION [ROERIG]31Current NDC, Legacy NDC, 2 package rows20250331_08d08721-1f4c-478a-8abf-d9c402d50553.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
VFENDVORICONAZOLERoerig08d08721-1f4c-478a-8abf-d9c402d505532026-03-20Warnings, Adverse reactionsExact identifier
application applno (NDA): 021267
application number: NDA021267
ndc (product): 0049-4190
VFENDVORICONAZOLERoerigdac26bcd-7a59-401f-9f66-a0649767cece2026-03-20Warnings, Adverse reactionsExact identifier
application applno (NDA): 021267
application number: NDA021267
VFENDVORICONAZOLERoerigce3ef5cf-3087-4d92-9d94-9eb8287228db2026-02-26Warnings, Adverse reactionsExact identifier
application applno (NDA): 021267
application number: NDA021267

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
352220Vfend 200 MG InjectionPSN08d08721-1f4c-478a-8abf-d9c402d5055333
351209voriconazole 200 MG InjectionPSN08d08721-1f4c-478a-8abf-d9c402d5055333
352220voriconazole 200 MG Injection [Vfend]SBD08d08721-1f4c-478a-8abf-d9c402d5055333
351209voriconazole 200 MG InjectionSCD08d08721-1f4c-478a-8abf-d9c402d5055333
352220Vfend 200 MG InjectionSY08d08721-1f4c-478a-8abf-d9c402d5055333

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
0049-4190-01000494190011 VIAL, SINGLE-USE in 1 CARTON (0049-4190-01) / 20 mL in 1 VIAL, SINGLE-USE2012-10-240000-00-00NoNoCurrent