Everolimus

Product NDC
0054-0604
11-digit product format
000540604
Labeler code
0054
Product ID
0054-0604_496ea375-42a1-422e-88ad-0b1c6df703aa
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Everolimus
Dosage form
TABLET
Route
ORAL
Labeler
Hikma Pharmaceuticals USA Inc.
Application
ANDA206133
Marketing category
ANDA
Marketing start
2021-11-18
Substance
EVEROLIMUS
Active strength
1 mg/1
Pharmacologic classes
Cytochrome P450 2D6 Inhibitors [MoA], Cytochrome P450 3A4 Inhibitors [MoA], Decreased Immunologic Activity [PE], Kinase Inhibitor [EPC], Protein Kinase Inhibitors [MoA], mTOR Inhibitor Immunosuppressant [EPC], mTOR Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 4 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A206133-001EVEROLIMUSEVEROLIMUS0.25MGTABLET / ORALAB2018-04-12
A206133-002EVEROLIMUSEVEROLIMUS0.5MGTABLET / ORALAB2018-04-12
A206133-003EVEROLIMUSEVEROLIMUS0.75MGTABLET / ORALAB2018-04-12
A206133-004EVEROLIMUSEVEROLIMUS1MGTABLET / ORALAB2021-11-18

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 4 matching rows.

Application-product, TE code table
Application-productTE code
A206133-001AB
A206133-002AB
A206133-003AB
A206133-004AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 160 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A206133-001EVEROLIMUS0.25MGTABLET / ORALAB2018-04-12caaa826d4ba7…
2026-08-18 06:07:402026-07A206133-002EVEROLIMUS0.5MGTABLET / ORALAB2018-04-12caaa826d4ba7…
2026-08-18 06:07:402026-07A206133-003EVEROLIMUS0.75MGTABLET / ORALAB2018-04-12caaa826d4ba7…
2026-08-18 06:07:402026-07A206133-004EVEROLIMUS1MGTABLET / ORALAB2021-11-18caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A206133-001EVEROLIMUS0.25MGTABLET / ORALAB2018-04-12011fe1cb6892…
2026-02-19 14:30 UTC2026-02A206133-002EVEROLIMUS0.5MGTABLET / ORALAB2018-04-12011fe1cb6892…
2026-02-19 14:30 UTC2026-02A206133-003EVEROLIMUS0.75MGTABLET / ORALAB2018-04-12011fe1cb6892…
2026-02-19 14:30 UTC2026-02A206133-004EVEROLIMUS1MGTABLET / ORALAB2021-11-18011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A206133-001EVEROLIMUS0.25MGTABLET / ORALAB2018-04-1231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A206133-002EVEROLIMUS0.5MGTABLET / ORALAB2018-04-1231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A206133-003EVEROLIMUS0.75MGTABLET / ORALAB2018-04-1231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A206133-004EVEROLIMUS1MGTABLET / ORALAB2021-11-1831067a03dcf5…
2025-08-23 18:47 UTC2025-08A206133-001EVEROLIMUS0.25MGTABLET / ORALAB2018-04-126a471c1ec25d…
2025-08-23 18:47 UTC2025-08A206133-002EVEROLIMUS0.5MGTABLET / ORALAB2018-04-126a471c1ec25d…
2025-08-23 18:47 UTC2025-08A206133-003EVEROLIMUS0.75MGTABLET / ORALAB2018-04-126a471c1ec25d…
2025-08-23 18:47 UTC2025-08A206133-004EVEROLIMUS1MGTABLET / ORALAB2021-11-186a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A206133-001EVEROLIMUS0.25MGTABLET / ORALAB2018-04-12fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A206133-002EVEROLIMUS0.5MGTABLET / ORALAB2018-04-12fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A206133-003EVEROLIMUS0.75MGTABLET / ORALAB2018-04-12fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A206133-004EVEROLIMUS1MGTABLET / ORALAB2021-11-18fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A206133-001EVEROLIMUS0.25MGTABLET / ORALAB2018-04-12b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A206133-002EVEROLIMUS0.5MGTABLET / ORALAB2018-04-12b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A206133-003EVEROLIMUS0.75MGTABLET / ORALAB2018-04-12b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A206133-004EVEROLIMUS1MGTABLET / ORALAB2021-11-18b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A206133-001EVEROLIMUS0.25MGTABLET / ORALAB2018-04-1203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A206133-002EVEROLIMUS0.5MGTABLET / ORALAB2018-04-1203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A206133-003EVEROLIMUS0.75MGTABLET / ORALAB2018-04-1203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A206133-004EVEROLIMUS1MGTABLET / ORALAB2021-11-1803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A206133-001EVEROLIMUS0.25MGTABLET / ORALAB2018-04-122680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A206133-002EVEROLIMUS0.5MGTABLET / ORALAB2018-04-122680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A206133-003EVEROLIMUS0.75MGTABLET / ORALAB2018-04-122680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A206133-004EVEROLIMUS1MGTABLET / ORALAB2021-11-182680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A206133-001EVEROLIMUS0.25MGTABLET / ORALAB2018-04-125bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A206133-002EVEROLIMUS0.5MGTABLET / ORALAB2018-04-125bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A206133-003EVEROLIMUS0.75MGTABLET / ORALAB2018-04-125bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A206133-004EVEROLIMUS1MGTABLET / ORALAB2021-11-185bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A206133-001EVEROLIMUS0.25MGTABLET / ORALAB2018-04-12d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A206133-002EVEROLIMUS0.5MGTABLET / ORALAB2018-04-12d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A206133-003EVEROLIMUS0.75MGTABLET / ORALAB2018-04-12d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A206133-004EVEROLIMUS1MGTABLET / ORALAB2021-11-18d8e5a09893c0…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 4 · 160 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A206133-001AB1caaa826d4ba7…
2026-08-18 06:07:402026-07A206133-002AB1caaa826d4ba7…
2026-08-18 06:07:402026-07A206133-003AB1caaa826d4ba7…
2026-08-18 06:07:402026-07A206133-004AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A206133-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A206133-002AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A206133-003AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A206133-004AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A206133-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A206133-002AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A206133-003AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A206133-004AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A206133-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A206133-002AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A206133-003AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A206133-004AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A206133-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A206133-002AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A206133-003AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A206133-004AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A206133-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A206133-002AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A206133-003AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A206133-004AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A206133-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A206133-002AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A206133-003AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A206133-004AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A206133-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A206133-002AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A206133-003AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A206133-004AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A206133-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A206133-002AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A206133-003AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A206133-004AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A206133-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A206133-002AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A206133-003AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A206133-004AB1d8e5a09893c0…

Additional Listing Data#

Finished product
Yes
Brand name base
Everolimus
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
EVEROLIMUS1 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
9HW64Q8G6GInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 4 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
977427Internal RxNorm lookup
977434Internal RxNorm lookup
977438Internal RxNorm lookup
2056895Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
cf2dd54b-7a1d-4401-9a01-75e68235e433Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
807eb842-6749-6eff-f9ce-2751c69fde93Product name420260122
151279ee-9f3c-b884-3327-05b3fa99d863Product name620251027

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0054-0604-21Everolimus60 in 1 BOTTLETABLET608

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0054-0604-21EA - Each0054-060472aa2ab0-b115-413f-bedc-2b37a8ba85b412021-12-08

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0054-0604EVEROLIMUS TABLET [HIKMA PHARMACEUTICALS USA INC.]8Current NDC, Legacy NDC, 1 package rows20250416_cf2dd54b-7a1d-4401-9a01-75e68235e433.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
EverolimusEVEROLIMUSHikma Pharmaceuticals USA Inc.cf2dd54b-7a1d-4401-9a01-75e68235e4332024-09-03Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 206133
application number: ANDA206133
ndc (product): 0054-0604

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
977427everolimus 0.25 MG Oral TabletPSNcf2dd54b-7a1d-4401-9a01-75e68235e4338
977434everolimus 0.5 MG Oral TabletPSNcf2dd54b-7a1d-4401-9a01-75e68235e4338
977438everolimus 0.75 MG Oral TabletPSNcf2dd54b-7a1d-4401-9a01-75e68235e4338
2056895everolimus 1 MG Oral TabletPSNcf2dd54b-7a1d-4401-9a01-75e68235e4338
977427everolimus 0.25 MG Oral TabletSCDcf2dd54b-7a1d-4401-9a01-75e68235e4338
977434everolimus 0.5 MG Oral TabletSCDcf2dd54b-7a1d-4401-9a01-75e68235e4338
977438everolimus 0.75 MG Oral TabletSCDcf2dd54b-7a1d-4401-9a01-75e68235e4338
2056895everolimus 1 MG Oral TabletSCDcf2dd54b-7a1d-4401-9a01-75e68235e4338
977434everolimus 500 MCG Oral TabletSYcf2dd54b-7a1d-4401-9a01-75e68235e4338
977438everolimus 750 MCG Oral TabletSYcf2dd54b-7a1d-4401-9a01-75e68235e4338

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0054-0604-210005406042160 TABLET in 1 BOTTLE (0054-0604-21) 60 tablet2021-11-180000-00-00NoNoCurrent