Lupron Depot

Product NDC
0074-3641
11-digit product format
000743641
Labeler code
0074
Product ID
0074-3641_691f9b76-b15b-47c9-8df9-8ebe91999b45
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
leuprolide acetate
Dosage form
KIT
Labeler
AbbVie Inc.
Application
NDA020011
Marketing category
NDA
Marketing start
1990-10-22
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N020011-001LUPRON DEPOTLEUPROLIDE ACETATE3.75MG/VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD1990-10-22
N020011-002LUPRON DEPOTLEUPROLIDE ACETATE3.75MGINJECTABLE / INJECTIONRLD, RS1995-10-26

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N020011-001LUPRON DEPOT3.75MG/VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD1990-10-22011fe1cb6892…
2026-02-19 14:30 UTC2026-02N020011-002LUPRON DEPOT3.75MGINJECTABLE / INJECTIONRLD, RS1995-10-26011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020011-001LUPRON DEPOT3.75MG/VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD1990-10-2231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020011-002LUPRON DEPOT3.75MGINJECTABLE / INJECTIONRLD, RS1995-10-2631067a03dcf5…
2025-08-23 18:47 UTC2025-08N020011-001LUPRON DEPOT3.75MG/VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD1990-10-226a471c1ec25d…
2025-08-23 18:47 UTC2025-08N020011-002LUPRON DEPOT3.75MGINJECTABLE / INJECTIONRLD, RS1995-10-266a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020011-001LUPRON DEPOT3.75MG/VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD1990-10-22fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020011-002LUPRON DEPOT3.75MGINJECTABLE / INJECTIONRLD, RS1995-10-26fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020011-001LUPRON DEPOT3.75MG/VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD1990-10-22b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020011-002LUPRON DEPOT3.75MGINJECTABLE / INJECTIONRLD, RS1995-10-26b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020011-001LUPRON DEPOT3.75MG/VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD1990-10-2203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020011-002LUPRON DEPOT3.75MGINJECTABLE / INJECTIONRLD, RS1995-10-2603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020011-001LUPRON DEPOT3.75MG/VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD1990-10-222680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020011-002LUPRON DEPOT3.75MGINJECTABLE / INJECTIONRLD, RS1995-10-262680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020011-001LUPRON DEPOT3.75MG/VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD1990-10-225bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020011-002LUPRON DEPOT3.75MGINJECTABLE / INJECTIONRLD, RS1995-10-265bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020011-001LUPRON DEPOT3.75MG/VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD1990-10-22d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020011-002LUPRON DEPOT3.75MGINJECTABLE / INJECTIONRLD, RS1995-10-26d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N020011-001LUPRON DEPOT3.75MG/VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD1990-10-22d06236e962d9…
2024-10-29 15:01 UTC2024-10N020011-002LUPRON DEPOT3.75MGINJECTABLE / INJECTIONRLD, RS1995-10-26d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020011-001LUPRON DEPOT3.75MG/VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD1990-10-2279d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020011-002LUPRON DEPOT3.75MGINJECTABLE / INJECTIONRLD, RS1995-10-2679d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020011-001LUPRON DEPOT3.75MG/VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD1990-10-22301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020011-002LUPRON DEPOT3.75MGINJECTABLE / INJECTIONRLD, RS1995-10-26301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N020011-001LUPRON DEPOT3.75MG/VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD1990-10-221e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N020011-002LUPRON DEPOT3.75MGINJECTABLE / INJECTIONRLD, RS1995-10-261e350fbaab3a…
2024-05-31 18:47 UTC2024-05N020011-001LUPRON DEPOT3.75MG/VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD1990-10-228072bd15b7f6…
2024-05-31 18:47 UTC2024-05N020011-002LUPRON DEPOT3.75MGINJECTABLE / INJECTIONRLD, RS1995-10-268072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N020011-001LUPRON DEPOT3.75MG/VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD1990-10-225c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N020011-002LUPRON DEPOT3.75MGINJECTABLE / INJECTIONRLD, RS1995-10-265c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N020011-001LUPRON DEPOT3.75MG/VIALINJECTABLE / INJECTIONRLD1990-10-225d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N020011-002LUPRON DEPOT3.75MGINJECTABLE / INJECTIONRLD, RS1995-10-265d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N020011-001LUPRON DEPOT3.75MG/VIALINJECTABLE / INJECTIONRLD1990-10-224b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N020011-002LUPRON DEPOT3.75MGINJECTABLE / INJECTIONRLD, RS1995-10-264b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N020011-001LUPRON DEPOT3.75MG/VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**INJECTABLE / INJECTIONRLD1990-10-2274a2ff9319b5…
2019-12-13 00:20 UTC2019-12N020011-002LUPRON DEPOT3.75MGINJECTABLE / INJECTIONRLD, RS1995-10-2674a2ff9319b5…
2022-03-09 01:35 UTC2022-03N020011-001LUPRON DEPOT3.75MG/VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD1990-10-22bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N020011-002LUPRON DEPOT3.75MGINJECTABLE / INJECTIONRLD, RS1995-10-26bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N020011-001LUPRON DEPOT3.75MG/VIAL **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**INJECTABLE / INJECTIONRLD1990-10-22782e0a99824c…
2021-12-28 21:50 UTC2021-12N020011-002LUPRON DEPOT3.75MGINJECTABLE / INJECTIONRLD, RS1995-10-26782e0a99824c…

Additional Listing Data#

Finished product
Yes
Brand name base
Lupron Depot
Listing expiration
2026-12-31

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 3 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
797544Internal RxNorm lookup
1115457Internal RxNorm lookup
1115459Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
00c486b0-bd7b-4898-834d-8c656e5e73cbAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
9e666f57-491f-16e0-fc75-cc1c9f2fe06fProduct name420250515
43944b95-6cc2-4eca-846a-a5e0ed070616Product name120240501
6c13b22c-b3ba-4127-b768-0132dd5ab0d1Product name120230829
f3ff4518-37fe-47a0-8a1e-6ce032a3efd5Product name120230829
2ed2d111-4d16-4e2a-9b09-7d196056f6c9Product name120211214
3c386306-c48a-413e-bb69-70cb268496f3Product name120210727
a62a50ac-1535-4461-9768-8ae703e2e9fbProduct name120210525
ce98e98f-fa6b-48a6-8ad2-9ef8e8098f26Product name120200925
7792dadb-52b6-46b6-8fdf-80b1171065b5Product name120180810
48747306-602a-42cc-957b-5b0c69158eeeProduct name120180604
23ede539-308f-46e5-817b-41ef23af8d40Product name120150930
425e3610-bbe8-4d70-9c46-8cf09afc4e4dProduct name120150930
ae18ed71-8057-40ec-987f-83624e50b906Product name120150122
9514609b-a2a9-f8ec-6ba6-3f8e5ee89877Product name120140508
bc07ef78-e82d-0c19-31f4-31f263780582Product name120140508
db5ebcdb-b6ae-21cd-4dc5-76cd84b5578bProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0074-3641-03Lupron Depot1 in 1 CARTONKIT11478
0074-3641-71Lupron Depot1 in 1 CARTONKIT11478

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0074-3641-03EA - Each0074-3641d33a7bbb-5a53-4b1b-942c-e6f387a5064012012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
ISOPROPYL ALCOHOLACTIVE INGREDIENTND2M416302LUPRON DEPOT (LEUPROLIDE ACETATE) KIT [ABBVIE INC.]1447
LEUPROLIDE ACETATEACTIVE INGREDIENT37JNS02E7VLUPRON DEPOT (LEUPROLIDE ACETATE) KIT [ABBVIE INC.]1447
ISOPROPYL ALCOHOLACTIVE MOIETYND2M416302LUPRON DEPOT (LEUPROLIDE ACETATE) KIT [ABBVIE INC.]1447
LEUPROLIDEACTIVE MOIETYEFY6W0M8TGLUPRON DEPOT (LEUPROLIDE ACETATE) KIT [ABBVIE INC.]1447
ACETIC ACIDINACTIVE INGREDIENTQ40Q9N063PLUPRON DEPOT (LEUPROLIDE ACETATE) KIT [ABBVIE INC.]1447
CARBOXYMETHYLCELLULOSE SODIUMINACTIVE INGREDIENTK679OBS311LUPRON DEPOT (LEUPROLIDE ACETATE) KIT [ABBVIE INC.]1447
GELATININACTIVE INGREDIENT2G86QN327LLUPRON DEPOT (LEUPROLIDE ACETATE) KIT [ABBVIE INC.]1447
MANNITOLINACTIVE INGREDIENT3OWL53L36ALUPRON DEPOT (LEUPROLIDE ACETATE) KIT [ABBVIE INC.]1447
POLYSORBATE 80INACTIVE INGREDIENT6OZP39ZG8HLUPRON DEPOT (LEUPROLIDE ACETATE) KIT [ABBVIE INC.]1447
WATERINACTIVE INGREDIENT059QF0KO0RLUPRON DEPOT (LEUPROLIDE ACETATE) KIT [ABBVIE INC.]1447

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0074-3641LUPRON DEPOT (LEUPROLIDE ACETATE) KIT [ABBVIE INC.]1476Current NDC, Legacy NDC, 2 package rows20241207_00c486b0-bd7b-4898-834d-8c656e5e73cb.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Lupron DepotLEUPROLIDE ACETATEAbbVie Inc.00c486b0-bd7b-4898-834d-8c656e5e73cb2025-09-18Warnings, Adverse reactionsExact identifier
application applno (NDA): 020011
application number: NDA020011
ndc (product): 0074-3641

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
797544isopropyl alcohol 70 % Medicated PadPSN00c486b0-bd7b-4898-834d-8c656e5e73cb1478
1115457leuprolide acetate 3.75 MG in 1 ML (1 month) Prefilled SyringePSN00c486b0-bd7b-4898-834d-8c656e5e73cb1478
1115459Lupron Depot 3.75 MG in 1 ML (1 month) Prefilled SyringePSN00c486b0-bd7b-4898-834d-8c656e5e73cb1478
11154591 ML leuprolide acetate 3.75 MG/ML Prefilled Syringe [Lupron]SBD00c486b0-bd7b-4898-834d-8c656e5e73cb1478
11154571 ML leuprolide acetate 3.75 MG/ML Prefilled SyringeSCD00c486b0-bd7b-4898-834d-8c656e5e73cb1478
797544isopropyl alcohol 0.7 ML/ML Medicated PadSCD00c486b0-bd7b-4898-834d-8c656e5e73cb1478
11154591 ML Lupron 3.75 MG/ML Prefilled SyringeSY00c486b0-bd7b-4898-834d-8c656e5e73cb1478
797544isopropyl alcohol 70 % Medicated PadSY00c486b0-bd7b-4898-834d-8c656e5e73cb1478
797544isopropyl alcohol 70 % Topical ClothSY00c486b0-bd7b-4898-834d-8c656e5e73cb1478
797544isopropyl alcohol 70 % Topical SwabSY00c486b0-bd7b-4898-834d-8c656e5e73cb1478
1115457leuprolide acetate 3.75 MG per 1 ML (1 month) Prefilled SyringeSY00c486b0-bd7b-4898-834d-8c656e5e73cb1478
1115457leuprolide acetate 3.75 MG per 1 ML Prefilled SyringeSY00c486b0-bd7b-4898-834d-8c656e5e73cb1478
1115459Lupron Depot 3.75 MG per 1 ML (1 month) Prefilled SyringeSY00c486b0-bd7b-4898-834d-8c656e5e73cb1478

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0074-3641-03000743641031 KIT in 1 CARTON (0074-3641-03) * 1 mL in 1 SYRINGE * 1 mL in 1 PACKET1 kit1990-10-220000-00-00NoNoCurrent
0074-3641-71000743641711 KIT in 1 CARTON (0074-3641-71) * 1 mL in 1 SYRINGE * 1 mL in 1 PACKET1 kit1990-10-220000-00-00YesNoCurrent