Metoprolol Tartrate and Hydrochlorothiazide

Product NDC: 0378-0434
11-digit product format: 003780434
Labeler code: 0378
Product ID: 0378-0434_2631c7b0-5af8-4967-b945-d3398b2147ba
Type: HUMAN PRESCRIPTION DRUG
Nonproprietary name: metoprolol tartrate and hydrochlorothiazide
Dosage form: TABLET
Route: ORAL
Labeler: Mylan Pharmaceuticals Inc.
Application: ANDA076792
Marketing category: ANDA
Marketing start: 2004-08-20
Substance: METOPROLOL TARTRATE; HYDROCHLOROTHIAZIDE
Active strength: 100; 25 mg/1; mg/1
Pharmacologic classes: Adrenergic beta-Antagonists [MoA], Increased Diuresis [PE], Thiazide Diuretic [EPC], Thiazides [CS], beta-Adrenergic Blocker [EPC]
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 44.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
A076792-001	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	HYDROCHLOROTHIAZIDE; METOPROLOL TARTRATE	25MG;50MG	TABLET / ORAL	AB		2004-08-20
A076792-002	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	HYDROCHLOROTHIAZIDE; METOPROLOL TARTRATE	25MG;100MG	TABLET / ORAL	AB		2004-08-20
A076792-003	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	HYDROCHLOROTHIAZIDE; METOPROLOL TARTRATE	50MG;100MG	TABLET / ORAL	AB	RS	2004-08-20

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 3 matching rows.

Application-product, TE code table
Application-product	TE code
A076792-001	AB
A076792-002	AB
A076792-003	AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 132 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Product TE source text	RLD / RS	Approval date	Source SHA-256
2026-10-15 13:18:30	2026-09	A076792-001	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;50MG	TABLET / ORAL	AB		2004-08-20	`c2088c7a36db…`
2026-10-15 13:18:30	2026-09	A076792-002	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;100MG	TABLET / ORAL	AB		2004-08-20	`c2088c7a36db…`
2026-10-15 13:18:30	2026-09	A076792-003	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	50MG;100MG	TABLET / ORAL	AB	RS	2004-08-20	`c2088c7a36db…`
2026-09-14 22:38:34	2026-08	A076792-001	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;50MG	TABLET / ORAL	AB		2004-08-20	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	A076792-002	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;100MG	TABLET / ORAL	AB		2004-08-20	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	A076792-003	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	50MG;100MG	TABLET / ORAL	AB	RS	2004-08-20	`84e616aacf4f…`
2026-08-18 06:07:40	2026-07	A076792-001	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;50MG	TABLET / ORAL	AB		2004-08-20	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	A076792-002	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;100MG	TABLET / ORAL	AB		2004-08-20	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	A076792-003	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	50MG;100MG	TABLET / ORAL	AB	RS	2004-08-20	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	A076792-001	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;50MG	TABLET / ORAL	AB		2004-08-20	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	A076792-002	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;100MG	TABLET / ORAL	AB		2004-08-20	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	A076792-003	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	50MG;100MG	TABLET / ORAL	AB		2004-08-20	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A076792-001	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;50MG	TABLET / ORAL	AB		2004-08-20	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A076792-002	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;100MG	TABLET / ORAL	AB		2004-08-20	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A076792-003	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	50MG;100MG	TABLET / ORAL	AB		2004-08-20	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	A076792-001	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;50MG	TABLET / ORAL	AB		2004-08-20	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	A076792-002	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;100MG	TABLET / ORAL	AB		2004-08-20	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	A076792-003	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	50MG;100MG	TABLET / ORAL	AB		2004-08-20	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A076792-001	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;50MG	TABLET / ORAL	AB		2004-08-20	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A076792-002	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;100MG	TABLET / ORAL	AB		2004-08-20	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A076792-003	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	50MG;100MG	TABLET / ORAL	AB		2004-08-20	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A076792-001	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;50MG	TABLET / ORAL	AB		2004-08-20	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A076792-002	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;100MG	TABLET / ORAL	AB		2004-08-20	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A076792-003	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	50MG;100MG	TABLET / ORAL	AB		2004-08-20	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A076792-001	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;50MG	TABLET / ORAL	AB		2004-08-20	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A076792-002	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;100MG	TABLET / ORAL	AB		2004-08-20	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A076792-003	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	50MG;100MG	TABLET / ORAL	AB		2004-08-20	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A076792-001	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;50MG	TABLET / ORAL	AB		2004-08-20	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A076792-002	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;100MG	TABLET / ORAL	AB		2004-08-20	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A076792-003	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	50MG;100MG	TABLET / ORAL	AB		2004-08-20	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A076792-001	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;50MG	TABLET / ORAL	AB		2004-08-20	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A076792-002	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;100MG	TABLET / ORAL	AB		2004-08-20	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A076792-003	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	50MG;100MG	TABLET / ORAL	AB		2004-08-20	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A076792-001	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;50MG	TABLET / ORAL	AB		2004-08-20	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A076792-002	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;100MG	TABLET / ORAL	AB		2004-08-20	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A076792-003	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	50MG;100MG	TABLET / ORAL	AB		2004-08-20	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	A076792-001	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;50MG	TABLET / ORAL	AB		2004-08-20	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	A076792-002	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;100MG	TABLET / ORAL	AB		2004-08-20	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	A076792-003	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	50MG;100MG	TABLET / ORAL	AB		2004-08-20	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A076792-001	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE	25MG;50MG	TABLET / ORAL	AB		2004-08-20	`79d66fd596c7…`

Observed Orange Book normalized TE history#

Normalized TE history page 2 of 4 · 132 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	TE code	Order	Source SHA-256
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A076792-002	AB	1	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A076792-003	AB	1	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A076792-001	AB	1	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A076792-002	AB	1	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A076792-003	AB	1	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	A076792-001	AB	1	`1e350fbaab3a…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	A076792-002	AB	1	`1e350fbaab3a…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	A076792-003	AB	1	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	A076792-001	AB	1	`8072bd15b7f6…`
2024-05-31 18:47 UTC	2024-05	A076792-002	AB	1	`8072bd15b7f6…`
2024-05-31 18:47 UTC	2024-05	A076792-003	AB	1	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	A076792-001	AB	1	`5c6f7cd8ea54…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	A076792-002	AB	1	`5c6f7cd8ea54…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	A076792-003	AB	1	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	A076792-001	AB	1	`5d02ea3f76ae…`
2022-04-08 23:34 UTC	2022-04	A076792-002	AB	1	`5d02ea3f76ae…`
2022-04-08 23:34 UTC	2022-04	A076792-003	AB	1	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	A076792-001	AB	1	`4b0b4de00fa7…`
2022-04-04 05:41 UTC	2022-04	A076792-002	AB	1	`4b0b4de00fa7…`
2022-04-04 05:41 UTC	2022-04	A076792-003	AB	1	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	A076792-001	AB	1	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	A076792-002	AB	1	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	A076792-003	AB	1	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	A076792-001	AB	1	`bb7c543d1eb4…`
2022-03-09 01:35 UTC	2022-03	A076792-002	AB	1	`bb7c543d1eb4…`
2022-03-09 01:35 UTC	2022-03	A076792-003	AB	1	`bb7c543d1eb4…`
2021-12-28 21:50 UTC	2021-12	A076792-001	AB	1	`782e0a99824c…`
2021-12-28 21:50 UTC	2021-12	A076792-002	AB	1	`782e0a99824c…`
2021-12-28 21:50 UTC	2021-12	A076792-003	AB	1	`782e0a99824c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	A076792-001	AB	1	`87673890dc5c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	A076792-002	AB	1	`87673890dc5c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	A076792-003	AB	1	`87673890dc5c…`
2021-03-12 10:30 UTC	2021-03	A076792-001	AB	1	`5aa47cf7b7d7…`
2021-03-12 10:30 UTC	2021-03	A076792-002	AB	1	`5aa47cf7b7d7…`
2021-03-12 10:30 UTC	2021-03	A076792-003	AB	1	`5aa47cf7b7d7…`
2020-12-22 03:56 UTC	2020-12	A076792-001	AB	1	`8869cabd3fbd…`
2020-12-22 03:56 UTC	2020-12	A076792-002	AB	1	`8869cabd3fbd…`
2020-12-22 03:56 UTC	2020-12	A076792-003	AB	1	`8869cabd3fbd…`
2020-11-12 02:37 UTC	2020-11	A076792-001	AB	1	`c0c555d07b60…`
2020-11-12 02:37 UTC	2020-11	A076792-002	AB	1	`c0c555d07b60…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Metoprolol Tartrate and Hydrochlorothiazide
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
METOPROLOL TARTRATE	100 mg/1
HYDROCHLOROTHIAZIDE	25 mg/1

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
c19ec24d-2c40-4b8d-7c20-500ffa3660a1	Product name	3	20260303
fac0d979-ed64-4395-be9a-fc0b6f8c0a4f	Product name	1	20260122
1199f4b7-b537-466c-9a1c-cb09131e9f8b	Product name	1	20251117
e1a63b6e-1877-c2c1-01a3-03ea2817aa6f	Product name	3	20251027
b15e9aa6-d523-ca97-480e-570e0543a342	Product name	4	20251024
07ea0487-5434-6896-2497-013a7ee4afbd	Product name	9	20250311
96816964-c075-ffa7-b7b8-d8570411a3b9	Product name	7	20250305
162cbc9d-ecc3-72ba-af9f-c76e2756ef54	Product name	3	20221207
9b303cd4-3186-2454-5706-3137e8b2dfd2	Product name	4	20221110
95ced987-af5e-4bea-8119-4e7d4558d21b	Product name	2	20200617
47fc2fe9-7afb-4be9-989d-787aaa6ad0ea	Product name	1	20200505
a8e65197-7914-7acf-c7ec-914d53819b34	Product name	3	20190624
8b67f333-47d1-8464-7ce4-406d3dbb295f	Product name	7	20190618
89a57420-ab44-5323-14f9-595159145f9b	Product name	2	20190612
c27b049d-3258-48cf-ebe5-08c236ae78e2	Product name	3	20190610
00fc2cf9-672f-3e0b-6afa-43cbc864d058	Product name	4	20180613
9ab5a42a-e77d-486b-bb1f-b343fe664ada	Product name	1	20180430
15b375b1-89c7-9594-80df-5a8c8864aee0	Product name	3	20180108
a7349398-661d-d9fc-46df-7e128bbd61d9	Product name	5	20171113
1bdb87cf-9b1f-6a51-5eb7-d182aaffaa3d	Product name	2	20170719
e0eeb018-194e-4b70-a57d-bac47a97b8ea	Product name	1	20160825
310125de-e7c0-730d-d178-98b990a0334a	Product name	2	20150324
55bffd21-17e1-ff02-2e8f-1f9a532b9502	Product name	2	20150320
ea069444-e874-4c28-833f-d2f52734ef4d	Product name	1	20150206
041df61b-f8b6-48a6-7b67-411e1412678b	Product name	1	20140508
0ad8bdca-888e-00da-648b-6a4de854a167	Product name	1	20140508
433a3439-b8f3-d13a-d2c8-9b221d628d60	Product name	1	20140508
59212689-39e5-a976-6d21-882d76d8079a	Product name	1	20140508
7613b1a5-acb6-4e5e-6048-c44deeeb1212	Product name	1	20140508
78637fb0-95c8-441f-e4b4-db1274b6f956	Product name	1	20140508
df89bd47-2db4-d593-ab37-d11953fd5536	Product name	1	20140508
f151007d-265d-9fbe-857d-1d44f1cb76ba	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
0378-0434-01	Metoprolol Tartrate and Hydrochlorothiazide	100 in 1 BOTTLE, PLASTIC	TABLET	100		12

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
0378-0434-01	EA - Each	0378-0434	5580a1e2-28b1-471d-80a6-79a52744fefb	1	2012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
HYDROCHLOROTHIAZIDE	ACTIVE INGREDIENT	0J48LPH2TH	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [MYLAN PHARMACEUTICALS INC.]	5
METOPROLOL TARTRATE	ACTIVE INGREDIENT	W5S57Y3A5L	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [MYLAN PHARMACEUTICALS INC.]	5
HYDROCHLOROTHIAZIDE	ACTIVE MOIETY	0J48LPH2TH	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [MYLAN PHARMACEUTICALS INC.]	5
METOPROLOL	ACTIVE MOIETY	GEB06NHM23	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [MYLAN PHARMACEUTICALS INC.]	5
ANHYDROUS LACTOSE	INACTIVE INGREDIENT	3SY5LH9PMK	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [MYLAN PHARMACEUTICALS INC.]	5
CELLULOSE, MICROCRYSTALLINE	INACTIVE INGREDIENT	OP1R32D61U	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [MYLAN PHARMACEUTICALS INC.]	5
CROSCARMELLOSE SODIUM	INACTIVE INGREDIENT	M28OL1HH48	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [MYLAN PHARMACEUTICALS INC.]	5
FD&C YELLOW NO. 6	INACTIVE INGREDIENT	H77VEI93A8	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [MYLAN PHARMACEUTICALS INC.]	5
MAGNESIUM STEARATE	INACTIVE INGREDIENT	70097M6I30	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [MYLAN PHARMACEUTICALS INC.]	5
POVIDONES	INACTIVE INGREDIENT	FZ989GH94E	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [MYLAN PHARMACEUTICALS INC.]	5
SILICON DIOXIDE	INACTIVE INGREDIENT	ETJ7Z6XBU4	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [MYLAN PHARMACEUTICALS INC.]	5
SODIUM LAURYL SULFATE	INACTIVE INGREDIENT	368GB5141J	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [MYLAN PHARMACEUTICALS INC.]	5
STARCH, CORN	INACTIVE INGREDIENT	O8232NY3SJ	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [MYLAN PHARMACEUTICALS INC.]	5
HYDROCHLOROTHIAZIDE	ACTIVE INGREDIENT	0J48LPH2TH	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [PHYSICIANS TOTAL CARE, INC.]	1
METOPROLOL TARTRATE	ACTIVE INGREDIENT	W5S57Y3A5L	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [PHYSICIANS TOTAL CARE, INC.]	1
HYDROCHLOROTHIAZIDE	ACTIVE MOIETY	0J48LPH2TH	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [PHYSICIANS TOTAL CARE, INC.]	1
METOPROLOL	ACTIVE MOIETY	GEB06NHM23	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [PHYSICIANS TOTAL CARE, INC.]	1
ANHYDROUS LACTOSE	INACTIVE INGREDIENT	3SY5LH9PMK	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [PHYSICIANS TOTAL CARE, INC.]	1
CELLULOSE, MICROCRYSTALLINE	INACTIVE INGREDIENT	OP1R32D61U	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [PHYSICIANS TOTAL CARE, INC.]	1
CROSCARMELLOSE SODIUM	INACTIVE INGREDIENT	M28OL1HH48	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [PHYSICIANS TOTAL CARE, INC.]	1
FD&C YELLOW NO. 6	INACTIVE INGREDIENT	H77VEI93A8	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [PHYSICIANS TOTAL CARE, INC.]	1
MAGNESIUM STEARATE	INACTIVE INGREDIENT	70097M6I30	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [PHYSICIANS TOTAL CARE, INC.]	1
POVIDONE	INACTIVE INGREDIENT	FZ989GH94E	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [PHYSICIANS TOTAL CARE, INC.]	1
SILICON DIOXIDE	INACTIVE INGREDIENT	ETJ7Z6XBU4	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [PHYSICIANS TOTAL CARE, INC.]	1
SODIUM LAURYL SULFATE	INACTIVE INGREDIENT	368GB5141J	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [PHYSICIANS TOTAL CARE, INC.]	1
STARCH, CORN	INACTIVE INGREDIENT	O8232NY3SJ	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [PHYSICIANS TOTAL CARE, INC.]	1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
0378-0434	METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE TABLET [MYLAN PHARMACEUTICALS INC.]	12	Current NDC, Legacy NDC, 1 package rows	20240413_b6cf0f43-8dc3-4535-b651-daf1f9e0336c.zip

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
W5S57Y3A5L	METOPROLOL TARTRATE	56392-17-7	METOPROLOL TARTRATE
0J48LPH2TH	HYDROCHLOROTHIAZIDE	58-93-5	HYDROCHLOROTHIAZIDE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
866479	metoprolol tartrate 100 MG / hydroCHLOROthiazide 25 MG Oral Tablet	PSN	b6cf0f43-8dc3-4535-b651-daf1f9e0336c	12
866491	metoprolol tartrate 100 MG / hydroCHLOROthiazide 50 MG Oral Tablet	PSN	b6cf0f43-8dc3-4535-b651-daf1f9e0336c	12
866482	metoprolol tartrate 50 MG / hydroCHLOROthiazide 25 MG Oral Tablet	PSN	b6cf0f43-8dc3-4535-b651-daf1f9e0336c	12
866479	hydrochlorothiazide 25 MG / metoprolol tartrate 100 MG Oral Tablet	SCD	b6cf0f43-8dc3-4535-b651-daf1f9e0336c	12
866482	hydrochlorothiazide 25 MG / metoprolol tartrate 50 MG Oral Tablet	SCD	b6cf0f43-8dc3-4535-b651-daf1f9e0336c	12
866491	hydrochlorothiazide 50 MG / metoprolol tartrate 100 MG Oral Tablet	SCD	b6cf0f43-8dc3-4535-b651-daf1f9e0336c	12
866479	HCTZ 25 MG / metoprolol tartrate 100 MG Oral Tablet	SY	b6cf0f43-8dc3-4535-b651-daf1f9e0336c	12
866482	HCTZ 25 MG / metoprolol tartrate 50 MG Oral Tablet	SY	b6cf0f43-8dc3-4535-b651-daf1f9e0336c	12
866491	HCTZ 50 MG / metoprolol tartrate 100 MG Oral Tablet	SY	b6cf0f43-8dc3-4535-b651-daf1f9e0336c	12
866479	metoprolol tartrate 100 MG / hydroCHLOROthiazide 25 MG Oral Tablet	PSN	67a67718-e59f-4988-8bfc-9b4ac103e370	1
866482	metoprolol tartrate 50 MG / hydroCHLOROthiazide 25 MG Oral Tablet	PSN	67a67718-e59f-4988-8bfc-9b4ac103e370	1
866479	hydrochlorothiazide 25 MG / metoprolol tartrate 100 MG Oral Tablet	SCD	67a67718-e59f-4988-8bfc-9b4ac103e370	1
866482	hydrochlorothiazide 25 MG / metoprolol tartrate 50 MG Oral Tablet	SCD	67a67718-e59f-4988-8bfc-9b4ac103e370	1
866479	HCTZ 25 MG / metoprolol tartrate 100 MG Oral Tablet	SY	67a67718-e59f-4988-8bfc-9b4ac103e370	1
866482	HCTZ 25 MG / metoprolol tartrate 50 MG Oral Tablet	SY	67a67718-e59f-4988-8bfc-9b4ac103e370	1

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
0378-0434-01	00378043401	100 TABLET in 1 BOTTLE, PLASTIC (0378-0434-01)	100 tablet	2004-08-20	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Metoprolol Tartrate and Hydrochlorothiazide	Mylan Pharmaceuticals Inc.	2026-09-15	HUMAN PRESCRIPTION DRUG LABEL	13
METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE - Physicians Total Care, Inc.	Physicians Total Care, Inc.	2011-03-31	HUMAN PRESCRIPTION DRUG LABEL	1