Tretinoin

Product NDC
0378-8090
11-digit product format
003788090
Labeler code
0378
Product ID
0378-8090_7f967c10-776a-4b9c-aeda-70276ff2747f
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Tretinoin
Dosage form
GEL
Route
TOPICAL
Labeler
Mylan Pharmaceuticals Inc.
Application
ANDA207955
Marketing category
ANDA
Marketing start
2018-11-14
Substance
TRETINOIN
Active strength
.5 mg/g
Pharmacologic classes
Retinoid [EPC], Retinoids [CS]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A207955-001TRETINOINTRETINOIN0.05%GEL / TOPICALAB2015-08-13

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A207955-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-13011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-1331067a03dcf5…
2025-08-23 18:47 UTC2025-08A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-136a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-13fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-13b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-1303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-132680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-135bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-13d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-13d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-1379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-13301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-131e350fbaab3a…
2024-05-31 18:47 UTC2024-05A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-138072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-135c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-135d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-134b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-1374a2ff9319b5…
2022-03-09 01:35 UTC2022-03A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-13bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-13782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-1387673890dc5c…
2021-03-12 10:30 UTC2021-03A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-135aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-138869cabd3fbd…
2020-11-12 02:37 UTC2020-11A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-13c0c555d07b60…
2019-12-14 00:12 UTC2019-12A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-133f01610625f2…
2019-09-15 20:21 UTC2019-09A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-13b00525d2431f…
2019-07-19 19:46 UTC2019-07A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-13ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-136a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-131c564ffb4f44…
2023-12-20 04:57 UTC2023-12A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-13ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-13a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-139b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-13a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-133f0d92c62455…
2023-05-13 08:27 UTC2023-05A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-13053a50430f4f…
2023-01-26 05:58 UTC2023-01A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-133bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-133a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-13f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-13e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A207955-001TRETINOIN0.05%GEL / TOPICALAB2015-08-13cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A207955-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A207955-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A207955-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A207955-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A207955-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A207955-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A207955-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A207955-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A207955-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A207955-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A207955-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A207955-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A207955-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A207955-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A207955-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A207955-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A207955-001AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A207955-001AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A207955-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A207955-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A207955-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03A207955-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A207955-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A207955-001AB1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A207955-001AB13f01610625f2…
2019-09-15 20:21 UTC2019-09A207955-001AB1b00525d2431f…
2019-07-19 19:46 UTC2019-07A207955-001AB1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A207955-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A207955-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A207955-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A207955-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A207955-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A207955-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A207955-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05A207955-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01A207955-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A207955-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A207955-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A207955-001AB1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A207955-001AB1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
Tretinoin
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
TRETINOIN.5 mg/g

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
5688UTC01RInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
245723Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
ce5f4f14-5e60-4cc1-bcb3-1fa9b8aa9cd5Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
b80ad7bc-1b6f-7ef4-1ed0-86cd9f459d60Product name620251124
1426d8f8-b7d5-4053-8554-613df00c0d86Product name220250616
0e7b8bf1-c46c-4de6-b26a-0c50e34364ecProduct name220250521
e3af9708-3004-7392-4046-5311eaa8bab5Product name320221128
13e7e7e3-e885-4c79-af6d-dad1aedbb06eProduct name120220128
503b047e-e62d-4745-9011-522b13bc701bProduct name120181206
7d41caa2-0b5d-9b03-ab8d-84271de26ef4Product name220170314
50ca9ff5-82dd-9971-4f2c-5845a76a8572Product name220150818
0a8118e4-08c6-b395-9ddc-d3e425e0493aProduct name120140508
233bcb0a-cf40-b0a1-b346-c83ac2f43579Product name120140508
85490a6b-2306-6bf2-c51b-eb63537dc2daProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0378-8090-45Tretinoin45 g in 1 TUBEGEL453
0378-8090-45Tretinoin1 in 1 CARTONGEL13

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0378-8090-45GM - Gram0378-80906fdf8a1d-2297-4608-be24-c11a1b7ac41212018-12-13

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0378-8090TRETINOIN GEL [MYLAN PHARMACEUTICALS INC.]3Current NDC, Legacy NDC, 2 package rows20220909_ce5f4f14-5e60-4cc1-bcb3-1fa9b8aa9cd5.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
TretinoinTRETINOINMylan Pharmaceuticals Inc.ce5f4f14-5e60-4cc1-bcb3-1fa9b8aa9cd52022-07-25Warnings, Adverse reactionsExact identifier
application applno (ANDA): 207955
application number: ANDA207955
ndc (product): 0378-8090

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
245723tretinoin 0.05 % Topical GelPSNce5f4f14-5e60-4cc1-bcb3-1fa9b8aa9cd53
245723tretinoin 0.0005 MG/MG Topical GelSCDce5f4f14-5e60-4cc1-bcb3-1fa9b8aa9cd53
245723tretinoin 0.05 % Topical GelSYce5f4f14-5e60-4cc1-bcb3-1fa9b8aa9cd53

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0378-8090-45003788090451 TUBE in 1 CARTON (0378-8090-45) / 45 g in 1 TUBE1 tube2018-11-140000-00-00NoNoCurrent