Xospata

Product NDC
0469-1425
11-digit product format
004691425
Labeler code
0469
Product ID
0469-1425_b1aef238-5cd9-47cb-a83f-1f5eac49f013
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
gilteritinib
Dosage form
TABLET
Route
ORAL
Labeler
Astellas Pharma US, Inc.
Application
NDA211349
Marketing category
NDA
Marketing start
2018-11-29
Substance
GILTERITINIB FUMARATE
Active strength
40 mg/1
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N211349-001XOSPATAGILTERITINIB FUMARATEEQ 40MG BASETABLET / ORALRLD, RS2018-11-28

Orange Book patents#

Current patent rows page 1 of 1 · 8 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N211349-00194874912030-07-28U-24562018-12-18
N211349-00189693362032-11-28Drug substance, Drug product2018-12-18
N211349-001107865002036-07-01Drug product2020-10-28
N211349-001119381302036-07-01Drug product2024-04-25
N211349-001119381312036-07-01Drug product2024-04-25
N211349-001119381322036-07-01Drug product2024-04-25
N211349-001119381332036-07-01Drug product2024-04-25
N211349-001119446202036-07-01Drug product2024-04-25

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-2831067a03dcf5…
2025-08-23 18:47 UTC2025-08N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-286a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-2803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-282680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-285bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-2879d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-281e350fbaab3a…
2024-05-31 18:47 UTC2024-05N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-288072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-285c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-285d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-284b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-2874a2ff9319b5…
2022-03-09 01:35 UTC2022-03N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-2887673890dc5c…
2021-03-12 10:30 UTC2021-03N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-285aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-288869cabd3fbd…
2020-11-12 02:37 UTC2020-11N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28c0c555d07b60…
2019-12-14 00:12 UTC2019-12N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-283f01610625f2…
2019-09-15 20:21 UTC2019-09N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28b00525d2431f…
2019-07-19 19:46 UTC2019-07N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-286a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-281c564ffb4f44…
2023-12-20 04:57 UTC2023-12N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-289b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-283f0d92c62455…
2023-05-13 08:27 UTC2023-05N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28053a50430f4f…
2023-01-26 05:58 UTC2023-01N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-283bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-283a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N211349-001XOSPATAEQ 40MG BASETABLET / ORALRLD, RS2018-11-28cb3db0bc1861…

Observed Orange Book patent history#

Patent history page 1 of 5 · 194 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N211349-00194874912030-07-28U-24562018-12-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211349-00189693362032-11-28Drug substance, Drug product2018-12-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211349-001107865002036-07-01Drug product2020-10-28011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211349-001119381302036-07-01Drug product2024-04-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211349-001119381312036-07-01Drug product2024-04-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211349-001119381322036-07-01Drug product2024-04-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211349-001119381332036-07-01Drug product2024-04-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02N211349-001119446202036-07-01Drug product2024-04-25011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211349-00194874912030-07-28U-24562018-12-1831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211349-00189693362032-11-28Drug substance, Drug product2018-12-1831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211349-001107865002036-07-01Drug product2020-10-2831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211349-001119381302036-07-01Drug product2024-04-2531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211349-001119381312036-07-01Drug product2024-04-2531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211349-001119381322036-07-01Drug product2024-04-2531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211349-001119381332036-07-01Drug product2024-04-2531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211349-001119446202036-07-01Drug product2024-04-2531067a03dcf5…
2025-08-23 18:47 UTC2025-08N211349-00194874912030-07-28U-24562018-12-186a471c1ec25d…
2025-08-23 18:47 UTC2025-08N211349-00189693362032-11-28Drug substance, Drug product2018-12-186a471c1ec25d…
2025-08-23 18:47 UTC2025-08N211349-001107865002036-07-01Drug product2020-10-286a471c1ec25d…
2025-08-23 18:47 UTC2025-08N211349-001119381302036-07-01Drug product2024-04-256a471c1ec25d…
2025-08-23 18:47 UTC2025-08N211349-001119381312036-07-01Drug product2024-04-256a471c1ec25d…
2025-08-23 18:47 UTC2025-08N211349-001119381322036-07-01Drug product2024-04-256a471c1ec25d…
2025-08-23 18:47 UTC2025-08N211349-001119381332036-07-01Drug product2024-04-256a471c1ec25d…
2025-08-23 18:47 UTC2025-08N211349-001119446202036-07-01Drug product2024-04-256a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211349-00194874912030-07-28U-24562018-12-18fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211349-00189693362032-11-28Drug substance, Drug product2018-12-18fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211349-001107865002036-07-01Drug product2020-10-28fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211349-001119381302036-07-01Drug product2024-04-25fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211349-001119381312036-07-01Drug product2024-04-25fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211349-001119381322036-07-01Drug product2024-04-25fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211349-001119381332036-07-01Drug product2024-04-25fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211349-001119446202036-07-01Drug product2024-04-25fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211349-00194874912030-07-28U-24562018-12-18b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211349-00189693362032-11-28Drug substance, Drug product2018-12-18b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211349-001107865002036-07-01Drug product2020-10-28b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211349-001119381302036-07-01Drug product2024-04-25b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211349-001119381312036-07-01Drug product2024-04-25b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211349-001119381322036-07-01Drug product2024-04-25b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211349-001119381332036-07-01Drug product2024-04-25b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211349-001119446202036-07-01Drug product2024-04-25b8a1b40f171c…

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 2 · 63 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N211349-001ODE-2222025-11-2831067a03dcf5…
2025-08-23 18:47 UTC2025-08N211349-001ODE-2222025-11-286a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N211349-001ODE-2222025-11-28fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N211349-001ODE-2222025-11-28b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N211349-001ODE-2222025-11-2803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N211349-001ODE-2222025-11-282680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N211349-001ODE-2222025-11-285bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N211349-001ODE-2222025-11-28d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N211349-001ODE-2222025-11-28d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N211349-001ODE-2222025-11-2879d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N211349-001ODE-2222025-11-28301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N211349-001ODE-2222025-11-281e350fbaab3a…
2024-05-31 18:47 UTC2024-05N211349-001ODE-2222025-11-288072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N211349-001NCE2023-11-285c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N211349-001ODE-2222025-11-285c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N211349-001NCE2023-11-285d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N211349-001ODE-2222025-11-285d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N211349-001NCE2023-11-284b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N211349-001ODE-2222025-11-284b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N211349-001NCE2023-11-2874a2ff9319b5…
2019-12-13 00:20 UTC2019-12N211349-001ODE-2222025-11-2874a2ff9319b5…
2022-03-09 01:35 UTC2022-03N211349-001NCE2023-11-28bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N211349-001ODE-2222025-11-28bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N211349-001NCE2023-11-28782e0a99824c…
2021-12-28 21:50 UTC2021-12N211349-001ODE-2222025-11-28782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N211349-001NCE2023-11-2887673890dc5c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N211349-001ODE-2222025-11-2887673890dc5c…
2021-03-12 10:30 UTC2021-03N211349-001NCE2023-11-285aa47cf7b7d7…
2021-03-12 10:30 UTC2021-03N211349-001ODE-2222025-11-285aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N211349-001NCE2023-11-288869cabd3fbd…
2020-12-22 03:56 UTC2020-12N211349-001ODE-2222025-11-288869cabd3fbd…
2020-11-12 02:37 UTC2020-11N211349-001NCE2023-11-28c0c555d07b60…
2020-11-12 02:37 UTC2020-11N211349-001ODE-2222025-11-28c0c555d07b60…
2019-12-14 00:12 UTC2019-12N211349-001NCE2023-11-283f01610625f2…
2019-12-14 00:12 UTC2019-12N211349-001ODE-2222025-11-283f01610625f2…
2019-09-15 20:21 UTC2019-09N211349-001NCE2023-11-28b00525d2431f…
2019-09-15 20:21 UTC2019-09N211349-001ODE-2222025-11-28b00525d2431f…
2019-07-19 19:46 UTC2019-07N211349-001NCE2023-11-28ea99ee380514…
2019-07-19 19:46 UTC2019-07N211349-001ODE-2222025-11-28ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N211349-001ODE-2222025-11-286a51e52b5d6a…

Additional Listing Data#

Finished product
Yes
Brand name base
Xospata
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
GILTERITINIB FUMARATE40 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
5RZZ0Z1GJTInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2105811Internal RxNorm lookup
2105817Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
b5ff59aa-9c0d-49a8-9053-1f179b482383Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
644c83e0-46ed-43a1-af4a-897574061bb2Product name120190328

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0469-1425-21Xospata1 in 1 CARTONTABLET110
0469-1425-21Xospata21 in 1 BOTTLETABLET2110
0469-1425-90Xospata1 in 1 CARTONTABLET110
0469-1425-90Xospata90 in 1 BOTTLETABLET9010

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0469-1425-90EA - Each0469-1425d04697ab-eeef-4d52-94e8-12433985a4b812018-12-13

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0469-1425XOSPATA (GILTERITINIB) TABLET [ASTELLAS PHARMA US, INC.]10Current NDC, Legacy NDC, 4 package rows20250125_b5ff59aa-9c0d-49a8-9053-1f179b482383.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
XospataGILTERITINIBAstellas Pharma US, Inc.b5ff59aa-9c0d-49a8-9053-1f179b4823832022-01-01Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 211349
application number: NDA211349
ndc (product): 0469-1425

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
2105811gilteritinib 40 MG Oral TabletPSNb5ff59aa-9c0d-49a8-9053-1f179b48238310
2105817XOSPATA 40 MG Oral TabletPSNb5ff59aa-9c0d-49a8-9053-1f179b48238310
2105817gilteritinib 40 MG Oral Tablet [Xospata]SBDb5ff59aa-9c0d-49a8-9053-1f179b48238310
2105811gilteritinib 40 MG Oral TabletSCDb5ff59aa-9c0d-49a8-9053-1f179b48238310
2105811gilteritinib (as gilteritinib fumarate 44.2 MG) 40 MG Oral TabletSYb5ff59aa-9c0d-49a8-9053-1f179b48238310
2105817Xospata (as gilteritinib fumarate 44.2 MG) 40 MG Oral TabletSYb5ff59aa-9c0d-49a8-9053-1f179b48238310

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0469-1425-21004691425211 BOTTLE in 1 CARTON (0469-1425-21) / 21 TABLET in 1 BOTTLE1 bottle2022-04-300000-00-00YesNoCurrent
0469-1425-90004691425901 BOTTLE in 1 CARTON (0469-1425-90) / 90 TABLET in 1 BOTTLE1 bottle2018-11-290000-00-00NoNoCurrent