NDC 0498-2421-01 - Pain Stoppers

This NDC is not currently matched to an FDA NDC product listing in FDA.report, but it is a valid NDC-form code. FDA.report is showing the available DailyMed label context for the product root.

Product NDC: 0498-2421
Requested NDC: 0498-2421-01
Package NDCs from labels: 0498-2421-01, 0498-2421-10, 0498-2421-25, 0498-2421-50
Manufacturer: Honeywell Safety Products USA, Inc | NORTH SAFETY DE MEXICALI, S. DE R.I. DE C.V.
Effective date: 2021-12-08
Current FDA listing: Not matched in FDA.report NDC product tables

DailyMed Labels#

Label, Manufacturer, Effective date table
Label	Manufacturer	Effective date	Type
0498-2422 & 0498-2421: Pain Stoppers	Honeywell Safety Products USA, Inc \| NORTH SAFETY DE MEXICALI, S. DE R.I. DE C.V.	2021-12-08	HUMAN OTC DRUG LABEL

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
ACETAMINOPHEN	ACTIVE INGREDIENT	362O9ITL9D	PAIN STOPPERS REGULAR (ACETAMINOPHEN, CAFFEINE, ASPIRIN, SALICYLAMIDE) TABLET [NORTH SAFETY PRODUCTS LLC]	1
ASPIRIN	ACTIVE INGREDIENT	R16CO5Y76E	PAIN STOPPERS REGULAR (ACETAMINOPHEN, CAFFEINE, ASPIRIN, SALICYLAMIDE) TABLET [NORTH SAFETY PRODUCTS LLC]	1
CAFFEINE	ACTIVE INGREDIENT	3G6A5W338E	PAIN STOPPERS REGULAR (ACETAMINOPHEN, CAFFEINE, ASPIRIN, SALICYLAMIDE) TABLET [NORTH SAFETY PRODUCTS LLC]	1
SALICYLAMIDE	ACTIVE INGREDIENT	EM8BM710ZC	PAIN STOPPERS REGULAR (ACETAMINOPHEN, CAFFEINE, ASPIRIN, SALICYLAMIDE) TABLET [NORTH SAFETY PRODUCTS LLC]	1
ACETAMINOPHEN	ACTIVE MOIETY	362O9ITL9D	PAIN STOPPERS REGULAR (ACETAMINOPHEN, CAFFEINE, ASPIRIN, SALICYLAMIDE) TABLET [NORTH SAFETY PRODUCTS LLC]	1
ASPIRIN	ACTIVE MOIETY	R16CO5Y76E	PAIN STOPPERS REGULAR (ACETAMINOPHEN, CAFFEINE, ASPIRIN, SALICYLAMIDE) TABLET [NORTH SAFETY PRODUCTS LLC]	1
CAFFEINE	ACTIVE MOIETY	3G6A5W338E	PAIN STOPPERS REGULAR (ACETAMINOPHEN, CAFFEINE, ASPIRIN, SALICYLAMIDE) TABLET [NORTH SAFETY PRODUCTS LLC]	1
SALICYLAMIDE	ACTIVE MOIETY	EM8BM710ZC	PAIN STOPPERS REGULAR (ACETAMINOPHEN, CAFFEINE, ASPIRIN, SALICYLAMIDE) TABLET [NORTH SAFETY PRODUCTS LLC]	1
CELLULOSE, MICROCRYSTALLINE	INACTIVE INGREDIENT	OP1R32D61U	PAIN STOPPERS REGULAR (ACETAMINOPHEN, CAFFEINE, ASPIRIN, SALICYLAMIDE) TABLET [NORTH SAFETY PRODUCTS LLC]	1
FD&C YELLOW NO. 6	INACTIVE INGREDIENT	H77VEI93A8	PAIN STOPPERS REGULAR (ACETAMINOPHEN, CAFFEINE, ASPIRIN, SALICYLAMIDE) TABLET [NORTH SAFETY PRODUCTS LLC]	1
MAGNESIUM STEARATE	INACTIVE INGREDIENT	70097M6I30	PAIN STOPPERS REGULAR (ACETAMINOPHEN, CAFFEINE, ASPIRIN, SALICYLAMIDE) TABLET [NORTH SAFETY PRODUCTS LLC]	1
POVIDONE K30	INACTIVE INGREDIENT	U725QWY32X	PAIN STOPPERS REGULAR (ACETAMINOPHEN, CAFFEINE, ASPIRIN, SALICYLAMIDE) TABLET [NORTH SAFETY PRODUCTS LLC]	1
STEARIC ACID	INACTIVE INGREDIENT	4ELV7Z65AP	PAIN STOPPERS REGULAR (ACETAMINOPHEN, CAFFEINE, ASPIRIN, SALICYLAMIDE) TABLET [NORTH SAFETY PRODUCTS LLC]	1

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 2 of 182 · 3,629 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
severe cold and cough daytime	ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE HYDROCHLORIDE	RARITAN PHARMACEUTICALS INC	3ce8508e-7d9d-4413-858a-8f952e760c01	2026-09-08	Warnings	Exact identifier unii: 362O9ITL9D
Multi Symptom Severe Cold	ACETAMINOPHEN, DEXTROMETHORPHAN HBR, PHENYLEPHRINE HCL	RARITAN PHARMACEUTICALS INC	d9606c9a-31b1-4121-9870-809a05f5b68a	2026-09-08	Warnings	Exact identifier unii: 362O9ITL9D
DESENFRIOL-ITO PLUS	ACETAMINOPHEN	OPMX LLC	5ac41edd-e845-734d-e063-6294a90a990a	2026-09-05	Warnings	Exact identifier unii: 362O9ITL9D
DRX CHOICE Regular Strength	ACETAMINOPHEN	Raritan Pharmaceuticals Inc.	8bacb24a-24d0-4175-b3e0-05efb5f5d373	2026-09-05	Warnings	Exact identifier unii: 362O9ITL9D
Severe Congestion and Pain	ACETAMINOPHEN, GUAIFENESIN, PHENYLEPHRINE HCL	Meijer Distribution, Inc.	49235f4f-e661-4a83-88ef-b9a956848777	2026-09-04	Warnings	Exact identifier unii: 362O9ITL9D
NIGHTTIME COLD AND FLU	ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, DOXYLAMINE SUCCINATE	Amazon.com Services LLC	774d2bde-9f57-4ced-800a-cada39c685ed	2026-09-04	Warnings	Exact identifier unii: 362O9ITL9D
Butalbital, Acetaminophen, Caffeine	BUTALBITAL, ACETAMINOPHEN, AND CAFFEINE	REMEDYREPACK INC.	dc2bb7fc-1722-4865-a02c-be5e5c211505	2026-09-03	Boxed warning, Warnings, Adverse reactions	Exact identifier unii: 3G6A5W338E unii: 362O9ITL9D
Feverall Jr. Strength	ACETAMINOPHEN	Sun Pharmaceutical Industries, Inc.	3561bbc3-53b0-4857-8b71-39e165ed95ce	2026-09-03	Warnings	Exact identifier unii: 362O9ITL9D
infants pain and fever	ACETAMINOPHEN	CVS Pharmacy	53b06c48-598e-41ad-ac7a-5508c195535c	2026-09-03	Warnings	Exact identifier unii: 362O9ITL9D
Aspirin Regular Strength	ASPIRIN	Cardinal Health 110, LLC. DBA Leader	2777beea-06d7-4ff5-ae4a-ad7a117dfb62	2026-09-02	Warnings	Exact identifier unii: R16CO5Y76E
AMAZON BASIC CARE ACETAMINOPHEN	ACETAMINOPHEN	Amazon.com Services LLC	113d92bf-f6c9-cc3d-e063-6294a90af033	2026-09-02	Warnings	Exact identifier unii: 362O9ITL9D
Childrens Multi Symptom Fever and Cold	ACETAMINOPHEN, CHLORPHENIRAMINE MALEATE, DEXTROMETHORPHAN HBR, PHENYLEPHRINE HCL	THE KROGER CO.	3daf7620-eb57-43d5-ba88-938b7221e346	2026-09-02	Warnings	Exact identifier unii: 362O9ITL9D
Extra Strength Pain Reliever	ACETAMINOPHEN	Shield Pharmaceuticals Corp.	78052120-40d8-4a3f-b72f-cc78ca76213b	2026-09-02	Warnings	Exact identifier unii: 362O9ITL9D
Nighttime Cold and Flu Multi Symptom Relief	ACETAMINOPHEN, DEXTROMETHORPHAN HBR, DOXYLAMINE SUCCINATE	Shield Pharmaceuticals Corp	decafa3a-3734-4161-bab0-121945881846	2026-09-02	Warnings	Exact identifier unii: 362O9ITL9D
Nighttime Severe Cold and Cough	ACETAMINOPHEN, DIPHENHYDRAMINE, PHENYLEPHRINE	KROGER COMPANY	7def6781-0881-46bf-ad7a-7a3f23a8d9f7	2026-09-02	Warnings	Exact identifier unii: 362O9ITL9D
Maximum Strength Cold Flu and Sore Throat	ACETAMINOPHEN, DEXTROMETHORPHAN HBR, GUAIFENESIN, PHENYLEPHRINE HCL	KROGER COMPANY	e1d27123-358f-4b0c-8e3b-33474750a0e6	2026-09-02	Warnings	Exact identifier unii: 362O9ITL9D
Kroger Nighttime Cold and Flu Relief	ACETAMINOPHEN, DEXTROMETHORPHAN HBR, DOXYLAMINE SUCCINATE	Kroger Company	c5ce0901-a5d7-46c4-8492-5a80c76e8517	2026-09-02	Warnings	Exact identifier unii: 362O9ITL9D
Maximum Strength Nighttime Cold and Flu	ACETAMINOPHEN , DIPHENHYDRAMINE HCL,PHENYLEPHRINE HCL	THE KROGER CO	058b2021-8a61-40b0-8a2e-a784d2b847fb	2026-09-02	Warnings	Exact identifier unii: 362O9ITL9D
Daytime Cold and Flu Relief	ACETAMINOHPEN, DEXTROMETHORPHAN HBR, GUAIFENESIN PHENYLEPHRINE HCL	The Kroger Co.	494e69ef-dc9f-4e14-b856-5eaf0f541a03	2026-09-02	Warnings	Exact identifier unii: 362O9ITL9D
Adult Low Dose Chewable Aspirin	ASPIRIN	Farmacias De Similares TX LLC	513ea306-74c6-96e3-e063-6394a90a8262	2026-09-01	Warnings	Exact identifier unii: R16CO5Y76E

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.