Preparation H Rapid Relief

Product NDC: 0573-0554
11-digit product format: 005730554
Labeler code: 0573
Product ID: 0573-0554_47e795a4-2ed4-9966-e063-6394a90a4955
Type: HUMAN OTC DRUG
Nonproprietary name: Glycerin, Lidocaine, Phenylephrine Hydrochloride
Dosage form: CLOTH
Route: TOPICAL
Labeler: Haleon US Holdings LLC
Application: M015
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2019-03-01
Substance: LIDOCAINE; PHENYLEPHRINE HYDROCHLORIDE; GLYCERIN
Active strength: 50; 2.5; 200 mg/1; mg/1; mg/1
Pharmacologic classes: Adrenergic alpha1-Agonists [MoA], Allergens [CS], Amide Local Anesthetic [EPC], Amides [CS], Antiarrhythmic [EPC], Cell-mediated Immunity [PE], Glycerol [CS], Increased Histamine Release [PE], Increased IgG Production [PE], Local Anesthesia [PE], Non-Standardized Chemical Allergen [EPC], alpha-1 Adrenergic Agonist [EPC]
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 2 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Source date
excluded package	package	0573-0554	0573-0554-10	D	Discontinued by firm		2026-10-15
excluded package	package	0573-0554	0573-0554-30	D	Discontinued by firm		2026-10-15

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 2 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Archive	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	0573-0554	0573-0554-30	D	Discontinued by firm		excluded / ndc_excluded.zip	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	0573-0554	0573-0554-10	D	Discontinued by firm		excluded / ndc_excluded.zip	`d630ba8d3edf…`	`732f749b63fb…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Preparation H Rapid Relief
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
LIDOCAINE	50 mg/1
PHENYLEPHRINE HYDROCHLORIDE	2.5 mg/1
GLYCERIN	200 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 3 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
98PI200987	Internal UNII lookup
04JA59TNSJ	Internal UNII lookup
PDC6A3C0OX	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1745438	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
49a93cfc-4ccd-4ef3-928f-901b9926f794	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
e4e263da-1c53-440f-bb80-b7a575843b5a	Product name	1	20260313
070fbed5-7088-434a-a7ce-f2a64d8d40ac	Product name	2	20260107
d2168cac-a261-415a-9c78-3522859fa720	Product name	3	20251124
bee66ce1-adb7-9d3b-67d9-582e4c54e80f	Product name	5	20250819
05a8cdd1-eeb8-409e-b938-0778225eca7d	Product name	4	20250221
e5b5c132-b15d-435b-9faa-2f74e5cadcf9	Product name	8	20250220
860a93dc-4863-49cc-b284-6bbe8191bc48	Product name	4	20250214
eaba870a-6a9d-442e-8643-87b3f558a451	Product name	1	20250117
f489e8f3-5c9e-4818-b539-a73587edcfc7	Product name	2	20240229
0f7ae452-206d-4fc4-868d-56fc47074084	Product name	1	20231011
9b4cf230-fd05-41d5-98c6-5db9ecb27b86	Product name	1	20230117
7d755fa1-1087-4dcd-98f0-6d4bba479a57	Product name	3	20210602
aed701d5-9c75-dfaf-7154-cde46179faea	Product name	9	20200313
b5abe2e3-39a1-43eb-9bff-f3c1653fe3df	Product name	2	20190930
fa8b5901-e681-426f-82fe-54f6d81ec698	Product name	4	20180619
332d03e4-aa24-4b11-841a-02bf41081920	Product name	1	20171221
c08ab52f-2fc8-4409-9d9f-ed8edc0bd070	Product name	1	20171221
e0b6c8be-f2bd-9f86-a9fc-3ed56ffaa814	Product name	3	20150910
68ed98f8-24c2-44a0-944a-6d36e82ce25a	Product name	1	20141222
1cd42bc2-a430-c72b-636d-991b235fbf80	Product name	1	20140508
42f3c020-f1b3-89bc-7bdc-e1f10e680485	Product name	1	20140508
49fa150c-f0de-cce7-3d9c-993ed81c5698	Product name	1	20140508
4d7ae718-ed00-bae8-2abe-9eaec1eef7ff	Product name	1	20140508
9137811f-f279-8640-5aeb-99fa2145d64d	Product name	1	20140508
9869efd7-d6dd-0665-5b67-53adbe6ef15e	Product name	1	20140508
e949165d-714d-e548-2b76-0cb5def16f30	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
0573-0554-10	Preparation H Rapid Relief	1 in 1 POUCH	CLOTH	1	6
0573-0554-10	Preparation H Rapid Relief	10 in 1 CARTON	CLOTH	10	6
0573-0554-20	Preparation H Rapid Relief	20 in 1 CARTON	CLOTH	20	6
0573-0554-20	Preparation H Rapid Relief	1 in 1 POUCH	CLOTH	1	6
0573-0554-30	Preparation H Rapid Relief	1 in 1 POUCH	CLOTH	1	6
0573-0554-30	Preparation H Rapid Relief	30 in 1 CARTON	CLOTH	30	6

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
0573-0554-10	EA - Each	0573-0554	a6176728-fbba-4596-86eb-d06177883237	1	2022-12-07

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
0573-0554	PREPARATION H RAPID RELIEF (GLYCERIN, LIDOCAINE, PHENYLEPHRINE HYDROCHLORIDE) CLOTH [HALEON US HOLDINGS LLC]	4	Current NDC, Legacy NDC, 6 package rows	20240302_49a93cfc-4ccd-4ef3-928f-901b9926f794.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 5 of 22 · 438 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
DRMITSUI MEDICAL HAEMORRHOID	PHENYLEPHRINE HCI WITCH HAZEL	YIYANGYUAN LIFE SCIENCES (HONG KONG) CO., LIMITED	51720221-893b-cade-e063-6394a90adaec	2026-05-10	Warnings	Exact identifier application number: M015
Glycerin	GLYCERIN SUPPOSITORIES	Neilmed Pharmaceuticals Inc.	374a2ca3-ee04-09a7-e063-6394a90ab760	2026-05-05	Warnings	Exact identifier application number: M015
Dr. Numb	LIDOCAINE	Shinpharma Inc	32ab24b4-dcec-4a09-e054-00144ff88e88	2026-04-30	Warnings	Exact identifier application number: M015
Dr. Numb	LIDOCAINE	Shinpharma Inc	c2c0cb17-401a-4ba2-aa04-64c9b43cd21b	2026-04-30	Warnings	Exact identifier application number: M015
Dr. Numb	LIDOCAINE	Shinpharma Inc	e840fba4-86ff-9da0-e053-2995a90a221a	2026-04-30	Warnings	Exact identifier application number: M015
FAMILY Wellness MEDICATED HEMORRHOIDAL WIPES	WITCH HAZEL	Family Dollar Stores, Inc	3f6f68c0-787a-48eb-b042-d4df90ea7e03	2026-04-17	Warnings	Exact identifier application number: M015
Equaline Hemorrhoidal	MINERAL OIL, PETROLATUM, PHENYLEPHRINE HCL	United Natural Foods, Inc. dba UNFI	a6ed1987-37ad-4bfd-8cea-f03426953f5a	2026-04-16	Warnings	Exact identifier application number: M015
Verdibliss HEMORRHOID RELIEF OINTMENTS	LIDOCAINE, PHENYLEPHRINE	Guangdong Quadrant Ecological Technology Co., Ltd.	4f1634d5-7667-b354-e063-6394a90a34e7	2026-04-10	Warnings	Exact identifier application number: M015
Hemorrhoidal Cream with Lidocaine	GLYCEROL, PHENYLEPHINE, PRAMOXINE, PETROLATUM	Trifecta Pharmaceuticals Usa Llc	4f1ef866-c4af-989b-e063-6294a90a148e	2026-04-10	Warnings	Exact identifier application number: M015
Thera Plus Hemorrhoidal	GLYCERIN, PHENYLEPHRINE HYDROCHLORIDE, PRAMOXINE HYDROCHLORIDE, WHITE PETROLATUM	Fourstar Group USA, Inc.	5d63bf97-29d2-4c71-97c3-85f425e86207	2026-04-07	Warnings	Exact identifier application number: M015
Walgreens Pain Relief with Lidocaine	LIDOCAINE, PHENYLEPHRINE HCL	Walgreens Co	3ce78f2f-0264-f406-e063-6294a90a7e03	2026-04-01	Warnings	Exact identifier application number: M015
Lidocaine	LIDOCAINE	YYBA Corp	5256a84a-8dac-8fd4-e063-6294a90a616c	2026-04-01	Warnings	Exact identifier application number: M015
Hemorrhoidal	LIDOCAINE, MINERAL OIL, PHENYLEPHRINE HCL, WHITE PETROLATUM	Walgreens Co	3d213ba8-3cbe-11c4-e063-6394a90ae016	2026-03-30	Warnings	Exact identifier application number: M015
Critic Aid Skin	ZINC OXIDE	Coloplast Corp	caaac1f0-437d-4185-8670-9f11b9cefe63	2026-03-30	Warnings	Exact identifier application number: M015
CVS Topical Analgesic Hemorrhoidal	DIBUCAINE	CVS PHARMACY,INC	b9e20531-3444-4955-b1d3-bb112340d230	2026-03-27	Warnings	Exact identifier application number: M015
Walgreens Moisture Barrier	WALGREENS MOISTURE BARRIER	Walgreens	44fc098c-1f5f-bf82-e063-6294a90a1405	2026-03-25	Warnings	Exact identifier application number: M015
Lidocaine	LIDOCAINE	YYBA Corp	472fe0d1-31a1-fded-e063-6394a90a4a66	2026-03-25	Warnings	Exact identifier application number: M015
Hemorrhoid Relief Cream	LIDOCAINE 5% ANORECTAL	ALAINA HEALTHCARE PRIVATE LIMITED	53b2c3b0-d729-44d6-bc64-a9e1c9351877	2026-03-23	Warnings	Exact identifier application number: M015
LIDOCAINE	LIDOCAINE	YYBA Corp	4db609cc-f329-62a4-e063-6394a90aefc1	2026-03-23	Warnings	Exact identifier application number: M015
Topical Hemorrhoid Relief Gel	MENTHOL, UNSPECIFIED FORM	Yantai Aien Biotechnology Co., Ltd.	4d6e6667-ab1c-de7c-e063-6294a90a0b9b	2026-03-20	Warnings	Exact identifier application number: M015

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
98PI200987	LIDOCAINE	137-58-6	LIDOCAINE
04JA59TNSJ	PHENYLEPHRINE HYDROCHLORIDE	61-76-7	PHENYLEPHRINE HYDROCHLORIDE
PDC6A3C0OX	GLYCERIN	56-81-5	GLYCERIN

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1745438	glycerin 20 % / lidocaine 5 % / phenylephrine HCl 0.25 % Medicated Pad	PSN	49a93cfc-4ccd-4ef3-928f-901b9926f794	6
1745438	glycerin 200 MG/ML / lidocaine 50 MG/ML / phenylephrine hydrochloride 2.5 MG/ML Medicated Pad	SCD	49a93cfc-4ccd-4ef3-928f-901b9926f794	6
1745438	glycerin 20 % / lidocaine 5 % / phenylephrine hydrochloride 0.25 % Medicated Pad	SY	49a93cfc-4ccd-4ef3-928f-901b9926f794	6

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
0573-0554-10	00573055410	10 POUCH in 1 CARTON (0573-0554-10) > 1 CLOTH in 1 POUCH	10 pouch	2019-03-01	0000-00-00	No	No	Current
0573-0554-20	00573055420	20 POUCH in 1 CARTON (0573-0554-20) / 1 CLOTH in 1 POUCH	20 pouch	2019-03-01	0000-00-00	No	No	Current
0573-0554-30	00573055430	30 POUCH in 1 CARTON (0573-0554-30) > 1 CLOTH in 1 POUCH	30 pouch	2019-03-01	0000-00-00	No	No	Current