Orphenadrine citrate

Product NDC
0641-6182
11-digit product format
006416182
Labeler code
0641
Product ID
0641-6182_dde13b7f-78fb-4b9a-bc16-a41bf45042be
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Orphenadrine citrate
Dosage form
INJECTION
Route
INTRAMUSCULAR; INTRAVENOUS
Labeler
Hikma Pharmaceuticals USA Inc.
Application
ANDA040463
Marketing category
ANDA
Marketing start
2003-04-28
Substance
ORPHENADRINE CITRATE
Active strength
60 mg/2mL
Pharmacologic classes
Centrally-mediated Muscle Relaxation [PE], Muscle Relaxant [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A040463-001ORPHENADRINE CITRATEORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-04

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A040463-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-04011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-0431067a03dcf5…
2025-08-23 18:47 UTC2025-08A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-046a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-04fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-04b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-0403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-042680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-045bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-04d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-04d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-0479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-04301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-041e350fbaab3a…
2024-05-31 18:47 UTC2024-05A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-048072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-045c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-045d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-044b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-0474a2ff9319b5…
2022-03-09 01:35 UTC2022-03A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-04bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-04782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-0487673890dc5c…
2021-03-12 10:30 UTC2021-03A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-045aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-048869cabd3fbd…
2020-11-12 02:37 UTC2020-11A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-04c0c555d07b60…
2019-12-14 00:12 UTC2019-12A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-043f01610625f2…
2019-09-15 20:21 UTC2019-09A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-04b00525d2431f…
2019-07-19 19:46 UTC2019-07A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-04ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-046a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-041c564ffb4f44…
2023-12-20 04:57 UTC2023-12A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-04ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-04a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-049b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-04a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-043f0d92c62455…
2023-05-13 08:27 UTC2023-05A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-04053a50430f4f…
2023-01-26 05:58 UTC2023-01A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-043bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-043a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-04f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-04e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A040463-001ORPHENADRINE CITRATE30MG/MLINJECTABLE / INJECTIONAP2003-03-04cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A040463-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A040463-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A040463-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A040463-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A040463-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A040463-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A040463-001AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A040463-001AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A040463-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A040463-001AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A040463-001AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A040463-001AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A040463-001AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A040463-001AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A040463-001AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A040463-001AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A040463-001AP14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A040463-001AP174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A040463-001AP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A040463-001AP1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A040463-001AP187673890dc5c…
2021-03-12 10:30 UTC2021-03A040463-001AP15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A040463-001AP18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A040463-001AP1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A040463-001AP13f01610625f2…
2019-09-15 20:21 UTC2019-09A040463-001AP1b00525d2431f…
2019-07-19 19:46 UTC2019-07A040463-001AP1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A040463-001AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A040463-001AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A040463-001AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A040463-001AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A040463-001AP19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A040463-001AP1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A040463-001AP13f0d92c62455…
2023-05-13 08:27 UTC2023-05A040463-001AP1053a50430f4f…
2023-01-26 05:58 UTC2023-01A040463-001AP13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A040463-001AP13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A040463-001AP1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A040463-001AP1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A040463-001AP1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
Orphenadrine citrate
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
ORPHENADRINE CITRATE60 mg/2mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
X0A40N8I4SInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
994541Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
ed406e8a-ec00-4711-ae2b-3c5af4f15438Available on FDA.report

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0641-6182-01Orphenadrine citrate2 mL in 1 VIALINJECTION25
0641-6182-10Orphenadrine citrate10 in 1 BOXINJECTION105
0641-6182-25Orphenadrine citrate25 in 1 BOXINJECTION255

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0641-6182-01ML - Milliliter0641-61825a19407b-dbd6-4797-b8d8-790c93f12ff212017-12-14
0641-6182-10ML - Milliliter0641-6182284eaedf-e0c9-4cbb-8ffd-b2aef877b3f312017-12-14
0641-6182-25ML - Milliliter0641-61822bd52cb8-76de-4bc5-ae3b-28e12563bf9d12024-09-09

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0641-6182ORPHENADRINE CITRATE INJECTION [HIKMA PHARMACEUTICALS USA INC.]5Current NDC, Legacy NDC, 3 package rows20240809_ed406e8a-ec00-4711-ae2b-3c5af4f15438.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Orphenadrine citrateORPHENADRINE CITRATEHikma Pharmaceuticals USA Inc.ed406e8a-ec00-4711-ae2b-3c5af4f154382024-08-08Warnings, Adverse reactionsExact identifier
application applno (ANDA): 040463
application number: ANDA040463
ndc (product): 0641-6182

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
994541orphenadrine citrate 60 MG in 2 ML InjectionPSNed406e8a-ec00-4711-ae2b-3c5af4f154385
9945412 ML orphenadrine citrate 30 MG/ML InjectionSCDed406e8a-ec00-4711-ae2b-3c5af4f154385
994541orphenadrine citrate 60 MG per 2 ML InjectionSYed406e8a-ec00-4711-ae2b-3c5af4f154385

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0641-6182-01006416182012 mL in 1 VIAL2 mlHistorical
0641-6182-100064161821010 VIAL in 1 BOX (0641-6182-10) > 2 mL in 1 VIAL (0641-6182-01) 10 vial2003-04-280000-00-00NoNoCurrent
0641-6182-250064161822525 BOX in 1 BOX (0641-6182-25) / 10 VIAL in 1 BOX (0641-6182-10) / 2 mL in 1 VIAL (0641-6182-01) 25 box2003-04-28NoNoCurrent