Hydroxyurea

Product NDC
0904-6939
11-digit product format
009046939
Labeler code
0904
Product ID
0904-6939_554e6427-7d26-4f99-b69b-10468b9bb014
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Hydroxyurea
Dosage form
CAPSULE
Route
ORAL
Labeler
Major Pharmaceuticals
Application
ANDA075340
Marketing category
ANDA
Marketing start
1999-02-24
Substance
HYDROXYUREA
Active strength
500 mg/1
Pharmacologic classes
Antimetabolite [EPC], Urea [CS]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A075340-001HYDROXYUREAHYDROXYUREA500MGCAPSULE / ORALAB1999-02-24

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A075340-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-24caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-24011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-2431067a03dcf5…
2025-08-23 18:47 UTC2025-08A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-246a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-24fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-24b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-2403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-242680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-245bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-24d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-24d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-2479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-24301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-241e350fbaab3a…
2024-05-31 18:47 UTC2024-05A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-248072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-245c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-245d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-244b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-2474a2ff9319b5…
2022-03-09 01:35 UTC2022-03A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-24bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-24782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-2487673890dc5c…
2021-03-12 10:30 UTC2021-03A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-245aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-248869cabd3fbd…
2020-11-12 02:37 UTC2020-11A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-24c0c555d07b60…
2019-12-14 00:12 UTC2019-12A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-243f01610625f2…
2019-09-15 20:21 UTC2019-09A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-24b00525d2431f…
2019-07-19 19:46 UTC2019-07A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-24ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-246a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-241c564ffb4f44…
2023-12-20 04:57 UTC2023-12A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-24ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-24a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-249b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-24a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-243f0d92c62455…
2023-05-13 08:27 UTC2023-05A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-24053a50430f4f…
2023-01-26 05:58 UTC2023-01A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-243bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-243a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-24f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A075340-001HYDROXYUREA500MGCAPSULE / ORALAB1999-02-24e64feba35796…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A075340-001AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A075340-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A075340-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A075340-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A075340-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A075340-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A075340-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A075340-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A075340-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A075340-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A075340-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A075340-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A075340-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A075340-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A075340-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A075340-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A075340-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A075340-001AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A075340-001AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A075340-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A075340-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A075340-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03A075340-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A075340-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A075340-001AB1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A075340-001AB13f01610625f2…
2019-09-15 20:21 UTC2019-09A075340-001AB1b00525d2431f…
2019-07-19 19:46 UTC2019-07A075340-001AB1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A075340-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A075340-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A075340-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A075340-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A075340-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A075340-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A075340-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05A075340-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01A075340-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A075340-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A075340-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A075340-001AB1e64feba35796…

Additional Listing Data#

Finished product
Yes
Brand name base
Hydroxyurea
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
HYDROXYUREA500 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
X6Q56QN5QCInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
197797Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
e76fd60e-7644-48c5-9857-3608a045000bAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
9be3ebe6-89e5-4e2f-8781-a389e7eb49e7Product name120250129
f76fb619-09b6-d149-3287-3661f7bc38cdProduct name320250124
62a0eedf-9497-47af-bccf-d51b8b15b067Product name120180307

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0904-6939-61Hydroxyurea100 in 1 CARTONCAPSULE1007
0904-6939-61Hydroxyurea1 in 1 BLISTER PACKCAPSULE17

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0904-6939-61EA - Each0904-69397ebe5f5c-e37d-4cdb-a7b9-99112ba38e2e12019-05-02

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0904-6939HYDROXYUREA CAPSULE [MAJOR PHARMACEUTICALS]5Current NDC, Legacy NDC, 2 package rows20241018_e76fd60e-7644-48c5-9857-3608a045000b.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
HydroxyureaHYDROXYUREAMajor Pharmaceuticalse76fd60e-7644-48c5-9857-3608a045000b2026-05-27Warnings, Adverse reactionsExact identifier
application applno (ANDA): 075340
application number: ANDA075340
ndc (product): 0904-6939
HydroxyureaHYDROXYUREAPar Health USA, LLC9e1bdd4b-043a-4cf6-b1ff-8de49e02b7a62026-05-07Warnings, Adverse reactionsExact identifier
application applno (ANDA): 075340
application number: ANDA075340
HydroxyureaHYDROXYUREAAmerican Health Packagingc84a2241-6c05-480f-8a5b-049e08c27d732026-03-02Warnings, Adverse reactionsExact identifier
application applno (ANDA): 075340
application number: ANDA075340

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
197797hydroxyurea 500 MG Oral CapsulePSNe76fd60e-7644-48c5-9857-3608a045000b7
197797hydroxyurea 500 MG Oral CapsuleSCDe76fd60e-7644-48c5-9857-3608a045000b7

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0904-6939-6100904693961100 BLISTER PACK in 1 CARTON (0904-6939-61) / 1 CAPSULE in 1 BLISTER PACK100 blister pack1999-02-240000-00-00NoNoCurrent