BENDAMUSTINE HYDROCHLORIDE

Product NDC
10019-079
11-digit product format
100190079
Labeler code
10019
Product ID
10019-079_007f13c9-9ca3-45f9-bbae-6806681efd06
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
bendamustine hydrochloride
Dosage form
INJECTION
Route
INTRAVENOUS
Labeler
Baxter Healthcare Corporation
Application
NDA216078
Marketing category
NDA
Marketing start
2022-12-15
Substance
BENDAMUSTINE HYDROCHLORIDE
Active strength
100 mg/1
Pharmacologic classes
Alkylating Activity [MoA], Alkylating Drug [EPC]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N216078-001BENDAMUSTINE HYDROCHLORIDEBENDAMUSTINE HYDROCHLORIDE100MG/4ML (25MG/ML)SOLUTION / INTRAVENOUSAPRLD, RS2022-12-15

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
N216078-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N216078-001BENDAMUSTINE HYDROCHLORIDE100MG/4ML (25MG/ML)SOLUTION / INTRAVENOUSAPRLD, RS2022-12-15011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N216078-001BENDAMUSTINE HYDROCHLORIDE100MG/4ML (25MG/ML)SOLUTION / INTRAVENOUSAPRLD, RS2022-12-1531067a03dcf5…
2025-08-23 18:47 UTC2025-08N216078-001BENDAMUSTINE HYDROCHLORIDE100MG/4ML (25MG/ML)SOLUTION / INTRAVENOUSAPRLD, RS2022-12-156a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N216078-001BENDAMUSTINE HYDROCHLORIDE100MG/4ML (25MG/ML)SOLUTION / INTRAVENOUSAPRLD, RS2022-12-15fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N216078-001BENDAMUSTINE HYDROCHLORIDE100MG/4ML (25MG/ML)SOLUTION / INTRAVENOUSAPRLD, RS2022-12-15b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N216078-001BENDAMUSTINE HYDROCHLORIDE100MG/4ML (25MG/ML)SOLUTION / INTRAVENOUSAPRLD, RS2022-12-1503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N216078-001BENDAMUSTINE HYDROCHLORIDE100MG/4ML (25MG/ML)SOLUTION / INTRAVENOUSAPRLD, RS2022-12-152680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N216078-001BENDAMUSTINE HYDROCHLORIDE100MG/4ML (25MG/ML)SOLUTION / INTRAVENOUSAPRLD, RS2022-12-155bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N216078-001BENDAMUSTINE HYDROCHLORIDE100MG/4ML (25MG/ML)SOLUTION / INTRAVENOUSAPRLD, RS2022-12-15d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N216078-001BENDAMUSTINE HYDROCHLORIDE100MG/4ML (25MG/ML)SOLUTION / INTRAVENOUSAPRLD, RS2022-12-15d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N216078-001BENDAMUSTINE HYDROCHLORIDE100MG/4ML (25MG/ML)SOLUTION / INTRAVENOUSAPRLD, RS2022-12-1579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N216078-001BENDAMUSTINE HYDROCHLORIDE100MG/4ML (25MG/ML)SOLUTION / INTRAVENOUSAPRLD, RS2022-12-15301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N216078-001BENDAMUSTINE HYDROCHLORIDE100MG/4ML (25MG/ML)SOLUTION / INTRAVENOUSAPRLD, RS2022-12-151e350fbaab3a…
2024-05-31 18:47 UTC2024-05N216078-001BENDAMUSTINE HYDROCHLORIDE100MG/4ML (25MG/ML)SOLUTION / INTRAVENOUSAPRLD, RS2022-12-158072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N216078-001BENDAMUSTINE HYDROCHLORIDE100MG/4ML (25MG/ML)SOLUTION / INTRAVENOUSAPRLD, RS2022-12-156a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N216078-001BENDAMUSTINE HYDROCHLORIDE100MG/4ML (25MG/ML)SOLUTION / INTRAVENOUSAPRLD, RS2022-12-151c564ffb4f44…
2023-12-20 04:57 UTC2023-12N216078-001BENDAMUSTINE HYDROCHLORIDE100MG/4ML (25MG/ML)SOLUTION / INTRAVENOUSAPRLD, RS2022-12-15ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N216078-001BENDAMUSTINE HYDROCHLORIDE100MG/4ML (25MG/ML)SOLUTION / INTRAVENOUSAPRLD, RS2022-12-15a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N216078-001BENDAMUSTINE HYDROCHLORIDE100MG/4ML (25MG/ML)SOLUTION / INTRAVENOUSAPRLD, RS2022-12-159b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N216078-001BENDAMUSTINE HYDROCHLORIDE100MG/4ML (25MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-12-15a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N216078-001BENDAMUSTINE HYDROCHLORIDE100MG/4ML (25MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-12-153f0d92c62455…
2023-05-13 08:27 UTC2023-05N216078-001BENDAMUSTINE HYDROCHLORIDE100MG/4ML (25MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-12-15053a50430f4f…
2023-01-26 05:58 UTC2023-01N216078-001BENDAMUSTINE HYDROCHLORIDE100MG/4ML (25MG/ML)SOLUTION / INTRAVENOUSRLD, RS2022-12-153bdfa0b2c4d7…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N216078-001BENDAMUSTINE HYDROCHLORIDE100MG/4ML (25MG/ML)SOLUTION / INTRAVENOUSAPRLD, RS2022-12-15a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N216078-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N216078-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08N216078-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N216078-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N216078-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N216078-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N216078-001AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N216078-001AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N216078-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N216078-001AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N216078-001AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N216078-001AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N216078-001AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N216078-001AP18072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N216078-001AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N216078-001AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12N216078-001AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N216078-001AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N216078-001AP19b2671bbb829…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N216078-001AP1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
BENDAMUSTINE HYDROCHLORIDE
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
BENDAMUSTINE HYDROCHLORIDE100 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
981Y8SX18MInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1726097Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
766b73e2-49bb-47f9-bbb1-44cfa1a3197eAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
d8a9046a-cb9e-4038-9878-7314b52d6527Product name120230919
dd915fc1-21b5-4853-a27d-6a309d663ab6Product name120230913
188c28c4-6cdd-493c-850f-0529f5e5dd03Product name120230912
c9aaa656-9de9-4780-9592-b48e28af9e6eProduct name120180723
c2696876-93f7-42b5-907d-853b57a286f7Product name520180626
7dce4968-39c1-46ed-87ca-cce62b5b5728Product name120151215

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
10019-079-01BENDAMUSTINE HYDROCHLORIDE1 in 1 VIAL, MULTI-DOSEINJECTION111
10019-079-01BENDAMUSTINE HYDROCHLORIDE1 in 1 CARTONINJECTION111

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
10019-079-01ML - Milliliter10019-079e1ef15fe-962c-4ca4-a542-c5acee90cc3312023-02-06

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
10019-079BENDAMUSTINE HYDROCHLORIDE INJECTION [BAXTER HEALTHCARE CORPORATION]9Current NDC, Legacy NDC, 2 package rows20250507_766b73e2-49bb-47f9-bbb1-44cfa1a3197e.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
BENDAMUSTINE HYDROCHLORIDEBENDAMUSTINE HYDROCHLORIDEBaxter Healthcare Corporation766b73e2-49bb-47f9-bbb1-44cfa1a3197e2025-02-10Warnings, Adverse reactionsExact identifier
application applno (NDA): 216078
application number: NDA216078
ndc (product): 10019-079

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1726097bendamustine HCl 25 MG/ML Injectable SolutionPSN766b73e2-49bb-47f9-bbb1-44cfa1a3197e11
1726097bendamustine hydrochloride 25 MG/ML Injectable SolutionSCD766b73e2-49bb-47f9-bbb1-44cfa1a3197e11

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
10019-079-01100190079011 VIAL, MULTI-DOSE in 1 CARTON (10019-079-01) / 1 INJECTION in 1 VIAL, MULTI-DOSE2022-12-150000-00-00NoNoCurrent